| Tubulin as a target for anticancer drugs: agents which interact with the mitotic spindle A Jordan, JA Hadfield, NJ Lawrence, AT McGown Medicinal research reviews 18 (4), 259-296, 1998 | 921 | 1998 |
| Potent antimitotic and cell growth inhibitory properties of substituted chalcones S Ducki, R Forrest, JA Hadfield, A Kendall, NJ Lawrence, AT McGown, ... Bioorganic & medicinal chemistry letters 8 (9), 1051-1056, 1998 | 541 | 1998 |
| Tubulin and microtubules as targets for anticancer drugs JA Hadfield, S Ducki, N Hirst, AT McGown Progress in Cell Cycle Research. 5, 309-326, 2003 | 354 | 2003 |
| Novel syntheses of cis and trans isomers of combretastatin A-4 K Gaukroger, JA Hadfield, LA Hepworth, NJ Lawrence, AT McGown The Journal of organic chemistry 66 (24), 8135-8138, 2001 | 230 | 2001 |
| The interaction with tubulin of a series of stilbenes based on combretastatin A-4 JA Woods, JA Hadfield, GR Pettit, BW Fox, AT McGown British journal of cancer 71 (4), 705-711, 1995 | 227 | 1995 |
| Synthesis and biological evaluation of 2-and 3-aminobenzo [b] thiophene derivatives as antimitotic agents and inhibitors of tubulin polymerization R Romagnoli, PG Baraldi, MD Carrion, CL Cara, D Preti, F Fruttarolo, ... Journal of medicinal chemistry 50 (9), 2273-2277, 2007 | 174 | 2007 |
| The total synthesis of an aurone isolated from Uvaria hamiltonii: aurones and flavones as anticancer agents NJ Lawrence, D Rennison, AT McGown, JA Hadfield Bioorganic & medicinal chemistry letters 13 (21), 3759-3763, 2003 | 172 | 2003 |
| Structural requirements for the interaction of combretastatins with tubulin: how important is the trimethoxy unit? K Gaukroger, JA Hadfield, NJ Lawrence, S Nolan, AT McGown Organic & biomolecular chemistry 1 (17), 3033-3037, 2003 | 170 | 2003 |
| The interaction of chalcones with tubulin NJ Lawrence, AT McGown, S Ducki, JA Hadfield Anti-cancer drug design 15 (2), 135-141, 2000 | 148 | 2000 |
| Linked parallel synthesis and MTT bioassay screening of substituted chalcones NJ Lawrence, D Rennison, AT McGown, S Ducki, LA Gul, JA Hadfield, ... Journal of combinatorial chemistry 3 (5), 421-426, 2001 | 130 | 2001 |
| Isoflavones inhibit intestinal epithelial cell proliferation and induce apoptosis in vitro C Booth, DF Hargreaves, JA Hadfield, AT McGown, CS Potten British Journal of Cancer 80 (10), 1550-1557, 1999 | 129 | 1999 |
| Comparison of different busulfan analogues for depletion of hematopoietic stem cells and promotion of donor-type chimerism in murine bone marrow transplant recipients GR Westerhof, RE Ploemacher, A Boudewijn, I Blokland, JH Dillingh, ... Cancer Research 60 (19), 5470-5478, 2000 | 113 | 2000 |
| Cytotoxic michael-type amine adducts of α-methylene lactones alantolactone and isoalantolactone NJ Lawrence, AT McGown, J Nduka, JA Hadfield, RG Pritchard Bioorganic & medicinal chemistry letters 11 (3), 429-431, 2001 | 110 | 2001 |
| Reaction of Baylis–Hillman products with Swern and Dess–Martin oxidants NJ Lawrence, JP Crump, AT McGown, JA Hadfield Tetrahedron Letters 42 (23), 3939-3941, 2001 | 109 | 2001 |
| The effect of ifosfamide and its metabolites on intracellular glutathione levels in vitro and in vivo MJ Lind, AT McGown, JA Hadfield, N Thatcher, D Crowther, BW Fox Biochemical pharmacology 38 (11), 1835-1840, 1989 | 104 | 1989 |
| Synthesis and anticancer activity of fluorinated analogues of combretastatin A-4 NJ Lawrence, LA Hepworth, D Rennison, AT McGown, JA Hadfield Journal of fluorine chemistry 123 (1), 101-108, 2003 | 102 | 2003 |
| Bioactivity and molecular modelling of diphenylsulfides and diphenylselenides JA Woods, JA Hadfield, AT McGown, BW Fox Bioorganic & medicinal chemistry 1 (5), 333-340, 1993 | 87 | 1993 |
| Antimitotic and cell growth inhibitory properties of combretastatin A-4-like ethers NJ Lawrence, D Rennison, M Woo, AT McGown, JA Hadfield Bioorganic & medicinal chemistry letters 11 (1), 51-54, 2001 | 78 | 2001 |
| Isolation of E-1-(4′-Hydroxyphenyl)-but-1-en-2-one from Scutellaria barbata S Ducki, JA Hadfield, NJ Lawrence, CY Liu, AT McGown, X Zhang Planta Medica 62 (02), 185-186, 1996 | 76 | 1996 |
| The synthesis of (E) and (Z)-combretastatins A-4 and a phenanthrene from Combretum caffrum NJ Lawrence, FA Ghani, LA Hepworth, JA Hadfield, AT McGown, ... Synthesis 1999 (09), 1656-1660, 1999 | 72 | 1999 |
