Laszlo Nagy
Laszlo Nagy
Professor and Co-Director, Johns Hopkins University School of Medicine and University of Debrecen
Verified email at - Homepage
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PPARγ promotes monocyte/macrophage differentiation and uptake of oxidized LDL
P Tontonoz, L Nagy, JGA Alvarez, VA Thomazy, RM Evans
Cell 93 (2), 241-252, 1998
Oxidized LDL regulates macrophage gene expression through ligand activation of PPARγ
L Nagy, P Tontonoz, JGA Alvarez, H Chen, RM Evans
Cell 93 (2), 229-240, 1998
Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300
H Chen, RJ Lin, RL Schiltz, D Chakravarti, A Nash, L Nagy, ML Privalsky, ...
Cell 90 (3), 569-580, 1997
A PPARγ-LXR-ABCA1 pathway in macrophages is involved in cholesterol efflux and atherogenesis
A Chawla, WA Boisvert, CH Lee, BA Laffitte, Y Barak, SB Joseph, D Liao, ...
Molecular cell 7 (1), 161-171, 2001
Nuclear receptor repression mediated by a complex containing SMRT, mSin3A, and histone deacetylase
L Nagy, HY Kao, D Chakravarti, RJ Lin, CA Hassig, DE Ayer, ...
Cell 89 (3), 373-380, 1997
Role of the histone deacetylase complex in acute promyelocytic leukaemia
RJ Lin, L Nagy, S Inoue, W Shao, WH Miller Jr, RM Evans
Nature 391 (6669), 811-814, 1998
PPAR-γ dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation
A Chawla, Y Barak, L Nagy, D Liao, P Tontonoz, RM Evans
Nature medicine 7 (1), 48-52, 2001
PPARs are a unique set of fatty acid regulated transcription factors controlling both lipid metabolism and inflammation
T Varga, Z Czimmerer, L Nagy
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1812 (8 …, 2011
Mechanism of corepressor binding and release from nuclear hormone receptors
L Nagy, HY Kao, JD Love, C Li, E Banayo, JT Gooch, V Krishna, ...
Genes & development 13 (24), 3209-3216, 1999
Structural basis for the activation of PPARγ by oxidized fatty acids
T Itoh, L Fairall, K Amin, Y Inaba, A Szanto, BL Balint, L Nagy, ...
Nature structural & molecular biology 15 (9), 924-931, 2008
Mechanism of the nuclear receptor molecular switch
L Nagy, JWR Schwabe
Trends in biochemical sciences 29 (6), 317-324, 2004
STAT6 transcription factor is a facilitator of the nuclear receptor PPARγ-regulated gene expression in macrophages and dendritic cells
A Szanto, BL Balint, ZS Nagy, E Barta, B Dezso, A Pap, L Szeles, ...
Immunity 33 (5), 699-712, 2010
Role for peroxisome proliferator-activated receptor α in oxidized phospholipid–induced synthesis of monocyte chemotactic protein-1 and interleukin-8 by endothelial cells
H Lee, W Shi, P Tontonoz, S Wang, G Subbanagounder, CC Hedrick, ...
Circulation research 87 (6), 516-521, 2000
Retinoid X receptors: X-ploring their (patho) physiological functions
A Szanto, V Narkar, Q Shen, IP Uray, PJA Davies, L Nagy
Cell Death & Differentiation 11 (2), S126-S143, 2004
Activation of retinoid X receptors induces apoptosis in HL-60 cell lines
L Nagy, VA Thomázy, GL Shipley, L Fésüs, W Lamph, RA Heyman, ...
Molecular and cellular biology 15 (7), 3540-3551, 1995
1, 25-dihydroxyvitamin D3 is an autonomous regulator of the transcriptional changes leading to a tolerogenic dendritic cell phenotype
L Széles, G Keresztes, D Töröcsik, Z Balajthy, L Krenács, S Póliska, ...
The Journal of Immunology 182 (4), 2074-2083, 2009
Nuclear hormone receptors enable macrophages and dendritic cells to sense their lipid environment and shape their immune response
L Nagy, A Szanto, I Szatmari, L Széles
Physiological reviews 92 (2), 739-789, 2012
PPARγ controls CD1d expression by turning on retinoic acid synthesis in developing human dendritic cells
I Szatmari, A Pap, R Rühl, JX Ma, PA Illarionov, GS Besra, ...
The Journal of experimental medicine 203 (10), 2351-2362, 2006
Peroxisome proliferator-activated receptor γ-regulated ABCG2 expression confers cytoprotection to human dendritic cells
I Szatmari, G Vámosi, P Brazda, BL Balint, S Benko, L Széles, V Jeney, ...
Journal of Biological Chemistry 281 (33), 23812-23823, 2006
PPARγ in immunity and inflammation: cell types and diseases
L Széles, D Töröcsik, L Nagy
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2007
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