Structure of the kinase domain of an imatinib-resistant Abl mutant in complex with the Aurora kinase inhibitor VX-680 MA Young, NP Shah, LH Chao, M Seeliger, ZV Milanov, WH Biggs III, ... Cancer research 66 (2), 1007-1014, 2006 | 350 | 2006 |
A mechanism for tunable autoinhibition in the structure of a human Ca2+/calmodulin-dependent kinase II holoenzyme LH Chao, MM Stratton, IH Lee, OS Rosenberg, J Levitz, DJ Mandell, ... Cell 146 (5), 732-745, 2011 | 279 | 2011 |
Intersubunit capture of regulatory segments is a component of cooperative CaMKII activation LH Chao, P Pellicena, S Deindl, LA Barclay, H Schulman, J Kuriyan Nature structural & molecular biology 17 (3), 264-272, 2010 | 138 | 2010 |
Two forms of Opa1 cooperate to complete fusion of the mitochondrial inner-membrane Y Ge, X Shi, S Boopathy, J McDonald, AW Smith, LH Chao elife 9, e50973, 2020 | 132 | 2020 |
Activation-triggered subunit exchange between CaMKII holoenzymes facilitates the spread of kinase activity M Stratton, IH Lee, M Bhattacharyya, SM Christensen, LH Chao, ... Elife 3, e01610, 2014 | 116 | 2014 |
Structural studies on the regulation of Ca2+/calmodulin dependent protein kinase II MM Stratton, LH Chao, H Schulman, J Kuriyan Current opinion in structural biology 23 (2), 292-301, 2013 | 103 | 2013 |
Sequential conformational rearrangements in flavivirus membrane fusion LH Chao, DE Klein, AG Schmidt, JM Peña, SC Harrison Elife 3, e04389, 2014 | 92 | 2014 |
Crystal structure of tobacco etch virus protease shows the protein C terminus bound within the active site CM Nunn, M Jeeves, MJ Cliff, GT Urquhart, RR George, LH Chao, ... Journal of molecular biology 350 (1), 145-155, 2005 | 82 | 2005 |
NNT mediates redox-dependent pigmentation via a UVB-and MITF-independent mechanism J Allouche, I Rachmin, K Adhikari, LM Pardo, JH Lee, AM McConnell, ... Cell 184 (16), 4268-4283. e20, 2021 | 42 | 2021 |
Identification and characterization of a novel broad-spectrum virus entry inhibitor Y Chou, C Cuevas, M Carocci, SH Stubbs, M Ma, DK Cureton, L Chao, ... Journal of virology 90 (9), 4494-4510, 2016 | 37 | 2016 |
Heterogeneity in human hippocampal CaMKII transcripts reveals allosteric hub-dependent regulation R Sloutsky, N Dziedzic, MJ Dunn, RM Bates, AP Torres-Ocampo, ... Science signaling 13 (641), eaaz0240, 2020 | 33 | 2020 |
Cell wall synthesis and remodelling dynamics determine division site architecture and cell shape in Escherichia coli PP Navarro, A Vettiger, VY Ananda, PM Llopis, C Allolio, TG Bernhardt, ... Nature Microbiology 7 (10), 1621-1634, 2022 | 32 | 2022 |
The tarantula toxin GxTx detains K+ channel gating charges in their resting conformation DC Tilley, JM Angueyra, KS Eum, H Kim, LH Chao, AW Peng, JT Sack Journal of General Physiology 151 (3), 292-315, 2019 | 31 | 2019 |
Cryo-EM insight into the structure of MTOR complex 1 and its interactions with Rheb and substrates LH Chao, J Avruch F1000Research 8, 2019 | 25 | 2019 |
How small-molecule inhibitors of dengue-virus infection interfere with viral membrane fusion LH Chao, J Jang, A Johnson, A Nguyen, NS Gray, PL Yang, SC Harrison Elife 7, e36461, 2018 | 23 | 2018 |
Absence of cardiolipin from the outer leaflet of a mitochondrial inner membrane mimic restricts Opa1-mediated fusion Y Ge, S Boopathy, TH Nguyen, CM Lugo, LH Chao Frontiers in Molecular Biosciences 8, 769135, 2021 | 9 | 2021 |
Correction: Activation-triggered subunit exchange between CaMKII holoenzymes facilitates the spread of kinase activity M Stratton, IH Lee, M Bhattacharyya, SM Christensen, LH Chao, ... Elife 3, e02490, 2014 | 9 | 2014 |
In situ architecture of Opa1-dependent mitochondrial cristae remodeling MY Fry, PP Navarro, P Hakim, VY Ananda, X Qin, JC Landoni, S Rath, ... The EMBO Journal 43 (3), 391-413, 2024 | 8 | 2024 |
Cell wall synthesis and remodeling dynamics determine bacterial division site architecture and cell shape PP Navarro, A Vettiger, VY Ananda, PM Llopis, C Allolio, TG Bernhardt, ... bioRxiv, 2021.10. 02.462887, 2021 | 4 | 2021 |
A natural fusion of flavodiiron, rubredoxin, and rubredoxin oxidoreductase domains is a self-sufficient water-forming oxidase of Trichomonas vaginalis EN Abdulaziz, TA Bell, B Rashid, ML Heacock, T Begic, OS Skinner, ... Journal of Biological Chemistry 298 (8), 2022 | 3 | 2022 |