PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65 C Kondapalli, A Kazlauskaite, N Zhang, HI Woodroof, DG Campbell, ... Open biology 2 (5), 120080, 2012 | 918 | 2012 |
Phosphoproteomic screening identifies Rab GTP ases as novel downstream targets of PINK 1 YC Lai, C Kondapalli, R Lehneck, JB Procter, BD Dill, HI Woodroof, ... The EMBO journal 34 (22), 2840-2861, 2015 | 185 | 2015 |
Phosphorylation of Parkin at Serine65 is essential for activation: elaboration of a Miro1 substrate-based assay of Parkin E3 ligase activity A Kazlauskaite, V Kelly, C Johnson, C Baillie, CJ Hastie, M Peggie, ... Open biology 4 (3), 130213, 2014 | 146 | 2014 |
Discovery of catalytically active orthologues of the Parkinson's disease kinase PINK1: analysis of substrate specificity and impact of mutations HI Woodroof, JH Pogson, M Begley, LC Cantley, M Deak, DG Campbell, ... Open biology 1 (3), 110012, 2011 | 106 | 2011 |
TigarB causes mitochondrial dysfunction and neuronal loss in PINK1 deficiency LJ Flinn, M Keatinge, S Bretaud, H Mortiboys, H Matsui, E De Felice, ... Annals of neurology 74 (6), 837-847, 2013 | 95 | 2013 |
Structure of PINK1 and mechanisms of Parkinson's disease-associated mutations A Kumar, J Tamjar, AD Waddell, HI Woodroof, OG Raimi, AM Shaw, ... Elife 6, e29985, 2017 | 93 | 2017 |
Kinase and channel activity of TRPM6 are co-ordinated by a dimerization motif and pocket interaction J van der Wijst, MG Blanchard, HI Woodroof, TJ Macartney, R Gourlay, ... Biochemical Journal 460 (2), 165-175, 2014 | 17 | 2014 |
.(2012) PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65 C Kondapalli, A Kazlauskaite, N Zhang, HI Woodroof, DG Campbell, ... Open Biol 2, 120080, 0 | 5 | |
Biochemical Characterisation of the Parkinson's Disease-associated Kinase PINK1: Insights from the Insect World HI Woodroof University of Dundee, 2014 | | 2014 |
Kinase and channel activity of TRPM6 are co-ordinated by a dimerization motif and pocket interaction. J Wijst, MG Blanchard, HI Woodroof, TJ Macartney, R Gourlay, ... | | 2014 |
PINK1 is activated by mitochondrial membrane potential R Alessi, MMK Muqit, R Gourlay, L Burchell, H Walden, TJ Macartney, ... | | 2012 |