| Intratumor heterogeneity and branched evolution revealed by multiregion sequencing M Gerlinger, AJ Rowan, S Horswell, J Larkin, D Endesfelder, E Gronroos, ... New England journal of medicine 366 (10), 883-892, 2012 | 8506 | 2012 |
| Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution C Abbosh, NJ Birkbak, GA Wilson, M Jamal-Hanjani, T Constantin, ... Nature 545 (7655), 446-451, 2017 | 1686 | 2017 |
| Spatial and temporal diversity in genomic instability processes defines lung cancer evolution EC De Bruin, N McGranahan, R Mitter, M Salm, DC Wedge, L Yates, ... Science 346 (6206), 251-256, 2014 | 1237 | 2014 |
| Replication stress links structural and numerical cancer chromosomal instability RA Burrell, SE McClelland, D Endesfelder, P Groth, MC Weller, N Shaikh, ... Nature 494 (7438), 492-496, 2013 | 901 | 2013 |
| Deterministic evolutionary trajectories influence primary tumor growth: TRACERx renal S Turajlic, H Xu, K Litchfield, A Rowan, S Horswell, T Chambers, ... Cell 173 (3), 595-610. e11, 2018 | 543 | 2018 |
| Control of Smad7 stability by competition between acetylation and ubiquitination E Gronroos, U Hellman, CH Heldin, J Ericsson Molecular cell 10 (3), 483-493, 2002 | 454 | 2002 |
| Tolerance of whole-genome doubling propagates chromosomal instability and accelerates cancer genome evolution SM Dewhurst, N McGranahan, RA Burrell, AJ Rowan, E Grönroos, ... Cancer discovery 4 (2), 175-185, 2014 | 421 | 2014 |
| Pervasive chromosomal instability and karyotype order in tumour evolution TBK Watkins, EL Lim, M Petkovic, S Elizalde, NJ Birkbak, GA Wilson, ... Nature 587 (7832), 126-132, 2020 | 266 | 2020 |
| YY1 inhibits the activation of the p53 tumor suppressor in response to genotoxic stress E Grönroos, AA Terentiev, T Punga, J Ericsson Proceedings of the National Academy of Sciences 101 (33), 12165-12170, 2004 | 265 | 2004 |
| Pyk2 and FAK regulate neurite outgrowth induced by growth factors and integrins I Ivankovic-Dikic, E Gronroos, A Blaukat, BU Barth, I Dikic Nature cell biology 2 (9), 574-581, 2000 | 263 | 2000 |
| Coactivator-dependent acetylation stabilizes members of the SREBP family of transcription factors V Giandomenico, M Simonsson, E Gronroos, J Ericsson Molecular and cellular biology 23 (7), 2587, 2003 | 260 | 2003 |
| Adaptor proteins Grb2 and Crk couple Pyk2 with activation of specific mitogen-activated protein kinase cascades A Blaukat, I Ivankovic-Dikic, E Grönroos, F Dolfi, G Tokiwa, K Vuori, ... Journal of Biological Chemistry 274 (21), 14893-14901, 1999 | 256 | 1999 |
| The balance between acetylation and deacetylation controls Smad7 stability M Simonsson, CH Heldin, J Ericsson, E Grönroos Journal of Biological Chemistry 280 (23), 21797-21803, 2005 | 220 | 2005 |
| Requirement for interaction of PI3-kinase p110α with RAS in lung tumor maintenance E Castellano, C Sheridan, MZ Thin, E Nye, B Spencer-Dene, ... Cancer cell 24 (5), 617-630, 2013 | 187 | 2013 |
| SETD2 loss-of-function promotes renal cancer branched evolution through replication stress and impaired DNA repair N Kanu, E Grönroos, P Martinez, RA Burrell, X Yi Goh, J Bartkova, ... Oncogene 34 (46), 5699-5708, 2015 | 183 | 2015 |
| Lung adenocarcinoma promotion by air pollutants W Hill, EL Lim, CE Weeden, C Lee, M Augustine, K Chen, FC Kuan, ... Nature 616 (7955), 159-167, 2023 | 174 | 2023 |
| The DNA binding activities of Smad2 and Smad3 are regulated by coactivator-mediated acetylation M Simonsson, M Kanduri, E Gronroos, CH Heldin, J Ericsson Journal of Biological Chemistry 281 (52), 39870-39880, 2006 | 147 | 2006 |
| Cancer-specific loss of p53 leads to a modulation of myeloid and T cell responses J Blagih, F Zani, P Chakravarty, M Hennequart, S Pilley, S Hobor, ... Cell reports 30 (2), 481-496. e6, 2020 | 126 | 2020 |
| Transforming growth factor β inhibits bone morphogenetic protein-induced transcription through novel phosphorylated Smad1/5-Smad3 complexes E Grönroos, IJ Kingston, A Ramachandran, RA Randall, P Vizán, CS Hill Molecular and cellular biology 32 (14), 2904-2916, 2012 | 115 | 2012 |
| BCL9L dysfunction impairs caspase-2 expression permitting aneuploidy tolerance in colorectal cancer C López-García, L Sansregret, E Domingo, N McGranahan, S Hobor, ... Cancer cell 31 (1), 79-93, 2017 | 99 | 2017 |
Charles SwantonFrancis Crick InstituteVerified email at crick.ac.uk
