| Longitudinal single-cell RNA sequencing of patient-derived primary cells reveals drug-induced infidelity in stem cell hierarchy A Sharma, EY Cao, V Kumar, X Zhang, HS Leong, AML Wong, ... Nature communications 9 (1), 4931, 2018 | 145 | 2018 |
| Synthesis and evaluation of pyrazolo [3, 4-b] pyridines and its structural analogues as TNF-α and IL-6 inhibitors SB Bharate, TR Mahajan, YR Gole, M Nambiar, TT Matan, ... Bioorganic & medicinal chemistry 16 (15), 7167-7176, 2008 | 116 | 2008 |
| Phenotype-driven precision oncology as a guide for clinical decisions one patient at a time S Chia, JL Low, X Zhang, XL Kwang, FT Chong, A Sharma, D Bertrand, ... Nature communications 8 (1), 435, 2017 | 84 | 2017 |
| Crystal structure of rat intestinal alkaline phosphatase–role of crown domain in mammalian alkaline phosphatases K Ghosh, DM Tagore, R Anumula, B Lakshmaiah, P Kumar, S Singaram, ... Journal of structural biology 184 (2), 182-192, 2013 | 48 | 2013 |
| New high-throughput screening identifies compounds that reduce viability specifically in liver cancer cells that express high levels of SALL4 by inhibiting oxidative … JL Tan, F Li, JZ Yeo, KJ Yong, MA Bassal, GH Ng, MY Lee, CY Leong, ... Gastroenterology 157 (6), 1615-1629. e17, 2019 | 47 | 2019 |
| Targeting codon 158 p53-mutant cancers via the induction of p53 acetylation LR Kong, RW Ong, TZ Tan, NAB Mohamed Salleh, M Thangavelu, ... Nature Communications 11 (1), 2086, 2020 | 28 | 2020 |
| A chemical genetic screen identifies Aurora kinases as a therapeutic target in EGFR T790M negative, gefitinib-resistant head and neck squamous cell carcinoma (HNSCC) JL Low, DP Lau, X Zhang, XL Kwang, N Rohatgi, JV Chan, FT Chong, ... EBioMedicine 64, 2021 | 15 | 2021 |
| Genome-wide screens identify specific drivers of mutant hTERT promoters R Shanmugam, MB Ozturk, JL Low, SC Akincilar, JYH Chua, ... Proceedings of the National Academy of Sciences 119 (3), e2105171119, 2022 | 12 | 2022 |
| Integrated Genomic Profiling and Drug Screening of Patient-Derived Cultures Identifies Individualized Copy Number-Dependent Susceptibilities Involving PI3K Pathway and 17q … RLY Wong, MRE Wong, CH Kuick, SE Saffari, MK Wong, SH Tan, ... Frontiers in oncology 11, 709525, 2021 | 3 | 2021 |
| Single-cell RNA-seq unveils divergent modes of chemoresistance in squamous cell carcinoma A Sharma, V Kumar, EY Cao, HS Leong, M Hakimullah, N Ramakrishnan, ... Mechanisms of Development, S114, 2017 | 1 | 2017 |
| Corrigendum to ‘A chemical genetic screen identifies Aurora kinases as a therapeutic target in EGFR T790M negative, gefitinib-resistant head and neck squamous cell carcinoma … JL Low, DP Lau, X Zhang, XL Kwang, N Rohatgi, JV Chan, FT Chong, ... EBioMedicine 66, 2021 | | 2021 |
| A chemical genetic screen identifies Aurora kinases as a therapeutic target in EGFR T790M negative, gefitinib-resistant head and neck squamous cell carcinoma (HNSCC)(vol 64 … JL Low, DP Lau, X Zhang, XL Kwang, N Rohatgi, JV Chan, FT Chong, ... EBIOMEDICINE 66, 2021 | | 2021 |
| A high-throughput chemical genetic screen reveals SALL4-induced metabolic vulnerabilities in cancer JL Tan, F Li, JZ Yeo, KJ Yong, MA Bassal, GH Ng, MY Lee, CY Leong, ... Cancer Research 80 (16_Supplement), 1788-1788, 2020 | | 2020 |
Ramanuj DasguptaGenome Institute of SingaporeVerified email at gis.a-star.edu.sg
