Development and characterization of self-assembling nanoparticles using a bio-inspired amphipathic peptide for gene delivery HO McCarthy, J McCaffrey, CM McCrudden, A Zholobenko, AA Ali, ... Journal of Controlled Release 189, 141-149, 2014 | 214 | 2014 |
Arginine‐rich peptide‐based mRNA nanocomplexes efficiently instigate cytotoxic T cell immunity dependent on the amphipathic organization of the peptide VK Udhayakumar, A De Beuckelaer, J McCaffrey, CM McCrudden, ... Advanced healthcare materials 6 (13), 1601412, 2017 | 145 | 2017 |
DNA vaccination for cervical cancer; a novel technology platform of RALA mediated gene delivery via polymeric microneedles AA Ali, CM McCrudden, J McCaffrey, JW McBride, G Cole, NJ Dunne, ... Nanomedicine: Nanotechnology, Biology and Medicine 13 (3), 921-932, 2017 | 103 | 2017 |
DNA vaccination for cervical cancer: Strategic optimisation of RALA mediated gene delivery from a biodegradable microneedle system G Cole, AA Ali, CM McCrudden, JW McBride, J McCaffrey, T Robson, ... European Journal of Pharmaceutics and Biopharmaceutics 127, 288-297, 2018 | 79 | 2018 |
DNA vaccination via RALA nanoparticles in a microneedle delivery system induces a potent immune response against the endogenous prostate cancer stem cell antigen G Cole, AA Ali, E McErlean, EJ Mulholland, A Short, CM McCrudden, ... Acta Biomaterialia 96, 480-490, 2019 | 74 | 2019 |
Microneedles: an innovative platform for gene delivery J McCaffrey, RF Donnelly, HO McCarthy Drug delivery and translational research 5, 424-437, 2015 | 63 | 2015 |
Transcending epithelial and intracellular biological barriers; a prototype DNA delivery device J McCaffrey, CM McCrudden, AA Ali, AS Massey, JW McBride, ... Journal of controlled release 226, 238-247, 2016 | 57 | 2016 |
Dissolving microneedles for DNA vaccination: Improving functionality via polymer characterization and RALA complexation G Cole, J McCaffrey, AA Ali, JW McBride, CM McCrudden, ... Human Vaccines & Immunotherapeutics 13 (1), 50-62, 2017 | 56 | 2017 |
Electroporation of a nanoparticle-associated DNA vaccine induces higher inflammation and immunity compared to its delivery with microneedle patches in pigs C Bernelin-Cottet, C Urien, J McCaffrey, D Collins, A Donadei, D McDaid, ... Journal of controlled release 308, 14-28, 2019 | 35 | 2019 |
Potentiating the anticancer properties of bisphosphonates by nanocomplexation with the cationic amphipathic peptide, RALA AS Massey, S Pentlavalli, R Cunningham, CM McCrudden, EM McErlean, ... Molecular pharmaceutics 13 (4), 1217-1228, 2016 | 35 | 2016 |
Cancer nanotechnology G Cole, J McCaffrey, AA Ali, HO McCarthy Cancer 6 (1), 1-23, 2015 | 34* | 2015 |
Gene therapy with RALA/iNOS composite nanoparticles significantly enhances survival in a model of metastatic prostate cancer CM McCrudden, JW McBride, J McCaffrey, EM McErlean, NJ Dunne, ... Cancer nanotechnology 9, 1-15, 2018 | 30 | 2018 |
DNA vaccination for prostate cancer: key concepts and considerations G Cole, J McCaffrey, AA Ali, HO McCarthy Cancer nanotechnology 6 (1), 2, 2015 | 28 | 2015 |
DNA vaccination for prostate cancer: key concepts and considerations G Cole, J McCaffrey, AA Ali, HO McCarthy Cancer nanotechnology 6 (1), 2, 2015 | 28 | 2015 |
Systemic RALA/iNOS nanoparticles: a potent gene therapy for metastatic breast cancer coupled as a biomarker of treatment CM McCrudden, JW McBride, J McCaffrey, AA Ali, NJ Dunne, VL Kett, ... Molecular Therapy-Nucleic Acids 6, 249-258, 2017 | 24 | 2017 |
Toll-like receptor agonists as adjuvants for inactivated porcine reproductive and respiratory syndrome virus (PRRSV) vaccine S Vreman, J McCaffrey, DJ Popma-de Graaf, H Nauwynck, HFJ Savelkoul, ... Veterinary immunology and immunopathology 212, 27-37, 2019 | 23 | 2019 |
Development of TMTP-1 targeted designer biopolymers for gene delivery to prostate cancer JW McBride, AS Massey, J McCaffrey, CM McCrudden, JA Coulter, ... International Journal of Pharmaceutics 500 (1-2), 144-153, 2016 | 11 | 2016 |
Early immune responses in skin and lymph node after skin delivery of Toll-like receptor agonists in neonatal and adult pigs S Vreman, JMJ Rebel, J McCaffrey, K Ledl, K Arkhipova, D Collins, ... Vaccine 39 (13), 1857-1869, 2021 | 6 | 2021 |
Stability consideration for cryopreserved starting material to facilitate large-scale production of ATMPs H Crookes, J McCaffrey, R Hawkins, R Guest Cytotherapy 22 (5), S142, 2020 | 5 | 2020 |
Molecular investigations into vaginal immunization with HIV gp41 antigenic construct H4A in a quick release solid dosage form A Pattani, PF McKay, RM Curran, J McCaffrey, PN Gupta, D Lowry, ... Vaccine 30 (17), 2778-2785, 2012 | 5 | 2012 |