Követés
Joanne McCaffrey
Joanne McCaffrey
Director, Process Sciences
E-mail megerősítve itt: instilbio.com
Cím
Hivatkozott rá
Hivatkozott rá
Év
Development and characterization of self-assembling nanoparticles using a bio-inspired amphipathic peptide for gene delivery
HO McCarthy, J McCaffrey, CM McCrudden, A Zholobenko, AA Ali, ...
Journal of Controlled Release 189, 141-149, 2014
2142014
Arginine‐rich peptide‐based mRNA nanocomplexes efficiently instigate cytotoxic T cell immunity dependent on the amphipathic organization of the peptide
VK Udhayakumar, A De Beuckelaer, J McCaffrey, CM McCrudden, ...
Advanced healthcare materials 6 (13), 1601412, 2017
1452017
DNA vaccination for cervical cancer; a novel technology platform of RALA mediated gene delivery via polymeric microneedles
AA Ali, CM McCrudden, J McCaffrey, JW McBride, G Cole, NJ Dunne, ...
Nanomedicine: Nanotechnology, Biology and Medicine 13 (3), 921-932, 2017
1032017
DNA vaccination for cervical cancer: Strategic optimisation of RALA mediated gene delivery from a biodegradable microneedle system
G Cole, AA Ali, CM McCrudden, JW McBride, J McCaffrey, T Robson, ...
European Journal of Pharmaceutics and Biopharmaceutics 127, 288-297, 2018
792018
DNA vaccination via RALA nanoparticles in a microneedle delivery system induces a potent immune response against the endogenous prostate cancer stem cell antigen
G Cole, AA Ali, E McErlean, EJ Mulholland, A Short, CM McCrudden, ...
Acta Biomaterialia 96, 480-490, 2019
742019
Microneedles: an innovative platform for gene delivery
J McCaffrey, RF Donnelly, HO McCarthy
Drug delivery and translational research 5, 424-437, 2015
632015
Transcending epithelial and intracellular biological barriers; a prototype DNA delivery device
J McCaffrey, CM McCrudden, AA Ali, AS Massey, JW McBride, ...
Journal of controlled release 226, 238-247, 2016
572016
Dissolving microneedles for DNA vaccination: Improving functionality via polymer characterization and RALA complexation
G Cole, J McCaffrey, AA Ali, JW McBride, CM McCrudden, ...
Human Vaccines & Immunotherapeutics 13 (1), 50-62, 2017
562017
Electroporation of a nanoparticle-associated DNA vaccine induces higher inflammation and immunity compared to its delivery with microneedle patches in pigs
C Bernelin-Cottet, C Urien, J McCaffrey, D Collins, A Donadei, D McDaid, ...
Journal of controlled release 308, 14-28, 2019
352019
Potentiating the anticancer properties of bisphosphonates by nanocomplexation with the cationic amphipathic peptide, RALA
AS Massey, S Pentlavalli, R Cunningham, CM McCrudden, EM McErlean, ...
Molecular pharmaceutics 13 (4), 1217-1228, 2016
352016
Cancer nanotechnology
G Cole, J McCaffrey, AA Ali, HO McCarthy
Cancer 6 (1), 1-23, 2015
34*2015
Gene therapy with RALA/iNOS composite nanoparticles significantly enhances survival in a model of metastatic prostate cancer
CM McCrudden, JW McBride, J McCaffrey, EM McErlean, NJ Dunne, ...
Cancer nanotechnology 9, 1-15, 2018
302018
DNA vaccination for prostate cancer: key concepts and considerations
G Cole, J McCaffrey, AA Ali, HO McCarthy
Cancer nanotechnology 6 (1), 2, 2015
282015
DNA vaccination for prostate cancer: key concepts and considerations
G Cole, J McCaffrey, AA Ali, HO McCarthy
Cancer nanotechnology 6 (1), 2, 2015
282015
Systemic RALA/iNOS nanoparticles: a potent gene therapy for metastatic breast cancer coupled as a biomarker of treatment
CM McCrudden, JW McBride, J McCaffrey, AA Ali, NJ Dunne, VL Kett, ...
Molecular Therapy-Nucleic Acids 6, 249-258, 2017
242017
Toll-like receptor agonists as adjuvants for inactivated porcine reproductive and respiratory syndrome virus (PRRSV) vaccine
S Vreman, J McCaffrey, DJ Popma-de Graaf, H Nauwynck, HFJ Savelkoul, ...
Veterinary immunology and immunopathology 212, 27-37, 2019
232019
Development of TMTP-1 targeted designer biopolymers for gene delivery to prostate cancer
JW McBride, AS Massey, J McCaffrey, CM McCrudden, JA Coulter, ...
International Journal of Pharmaceutics 500 (1-2), 144-153, 2016
112016
Early immune responses in skin and lymph node after skin delivery of Toll-like receptor agonists in neonatal and adult pigs
S Vreman, JMJ Rebel, J McCaffrey, K Ledl, K Arkhipova, D Collins, ...
Vaccine 39 (13), 1857-1869, 2021
62021
Stability consideration for cryopreserved starting material to facilitate large-scale production of ATMPs
H Crookes, J McCaffrey, R Hawkins, R Guest
Cytotherapy 22 (5), S142, 2020
52020
Molecular investigations into vaginal immunization with HIV gp41 antigenic construct H4A in a quick release solid dosage form
A Pattani, PF McKay, RM Curran, J McCaffrey, PN Gupta, D Lowry, ...
Vaccine 30 (17), 2778-2785, 2012
52012
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Cikkek 1–20