Generation of knock-out primary and expanded human NK cells using Cas9 ribonucleoproteins MN Kararoudi, H Dolatshad, P Trikha, SRA Hussain, E Elmas, JA Foltz, ... JoVE (Journal of Visualized Experiments), e58237, 2018 | 67 | 2018 |
Lunatic fringe-mediated notch signaling regulates adult hippocampal neural stem cell maintenance F Semerci, WT Choi, A Bajic, A Thakkar, JM Encinas, F Depreux PMID, 2017 | 51 | 2017 |
TGFβ imprinting during activation promotes natural killer cell cytokine hypersecretion JA Foltz, JE Moseman, A Thakkar, N Chakravarti, DA Lee Cancers 10 (11), 423, 2018 | 41 | 2018 |
CD28 and 41BB costimulation enhances the effector function of CD19-specific engager T cells MP Velasquez, A Szoor, A Vaidya, A Thakkar, P Nguyen, MF Wu, H Liu, ... Cancer immunology research 5 (10), 860-870, 2017 | 36 | 2017 |
Defining the AHR-regulated transcriptome in NK cells reveals gene expression programs relevant to development and function P Trikha, JE Moseman, A Thakkar, AR Campbell, E Elmas, JA Foltz, ... Blood Advances 5 (22), 4605-4618, 2021 | 13 | 2021 |
A phase i clinical trial testing the safety of il-21-expanded, universally alloreactive donor-derived natural killer cells for relapsed/refractory acute myeloid leukemia and … S Vasu, N Sharma, AR Walker, SA Wall, JS Blachly, GK Behbehani, ... Blood 138, 1732, 2021 | 2 | 2021 |
Non-invasive fluorescence imaging for tracking immune cells in preclinical models of immunotherapy DAL Marcelo de Souza Fernandes Pereira, Aarohi Thakkar Methods in Cell Biology, https://www.sciencedirect.com/science/ar, 2021 | 2* | 2021 |
Use of highly characterized EBV-Specific T Cells outside of the immediate Post-Transplant setting RH Rouce, A Thakkar, S Sharma, N Shah, A Reyna, CA Ramos, ... Cytotherapy 21 (5), e3, 2019 | 2 | 2019 |
Automated closed-system large-scale expansion of clinical-grade natural killer cells A Thakkar, RY Igarashi, DA Lee Cytotherapy 21 (5), S31-S32, 2019 | 2 | 2019 |
Deletion of Glycogen Synthase Kinase 3 Beta Reprograms NK Cell Metabolism MSF Pereira, K Sorathia, Y Sezgin, A Thakkar, C Maguire, PL Collins, ... Cancers 15 (3), 705, 2023 | 1 | 2023 |
Immunotherapy: late breaking abstract: a phase I study of universal donor TGFβ-imprinted NK cell therapy in combination with carboplatin for canine osteosarcoma A Thakkar, W Dirksen, D Nielsen, PE Yaxley, C Cash, E Troy, DA Lee, ... Cytotherapy 24 (5), S25, 2022 | 1 | 2022 |
Development of surrogate potency assays for cellular immunotherapies A Thakkar, J Muszynski, MW Hall, DA Lee Cytotherapy 21 (5), S32, 2019 | 1 | 2019 |
Use of highly characterized EBV-specific T cells for treatment of EBV+ lymphoma outside of the HSCT setting RH Rouce, N Shah, A Thakkar, S Sharma, A Reyna, H Zhang, B Mehta, ... Cytotherapy 19 (5), S43, 2017 | 1 | 2017 |
Costimulation to enhance the antitumor activity of CD19 eng T cells M Velasquez, D Torres, A Thakkar, S Kakarla, CA Barth, S Xiao-Tong, ... Journal for ImmunoTherapy of Cancer 3 (Suppl 2), 2015 | 1 | 2015 |
Results of a phase I trial with Haploidentical mbIL‐21 ex vivo expanded NK cells for patients with multiply relapsed and refractory AML SO Ciurea, P Kongtim, S Srour, J Chen, D Soebbing, E Shpall, K Rezvani, ... American journal of hematology 99 (5), 890-899, 2024 | | 2024 |
Overcoming immune suppression with tgf-b resistant nk cells DA Lee, P Trikha, A Thakkar, J Foltz, MN Kararoudi, JE Moseman US Patent App. 17/922,248, 2023 | | 2023 |
Immunotherapy: RAPID GENERATION OF CMV-SPECIFIC CD19 CAR T CELLS: PROTOCOL OPTIMIZATION AND CMV-CD19 CAR T CELL CHARACTERIZATION M Lamb, A Thakkar, DA Lee Cytotherapy 25 (6), S235, 2023 | | 2023 |
A direct comparison of CAR NK cells and CAR T cells for CD19+ malignancies A Thakkar, D Lee, M Lamb PEDIATRIC BLOOD & CANCER 69, 2022 | | 2022 |
A PHASE I STUDY OF UNIVERSAL DONOR TGF beta-IMPRINTED NK CELL THERAPY IN COMBINATION WITH CARBOPLATIN FOR CANINE OSTEOSARCOMA A Thakkar, W Dirksen, D Nielsen, PE Yaxley, C Cash, E Troy, DA Lee, ... CYTOTHERAPY 24 (5), S25-S25, 2022 | | 2022 |
Use of a stimulating agent to assay immune cell potency DA Lee, A Thakkar, M Hall, J Muszynski US Patent App. 17/431,276, 2022 | | 2022 |