DC isoketal-modified proteins activate T cells and promote hypertension A Kirabo, V Fontana, APC De Faria, R Loperena, CL Galindo, J Wu, ... The Journal of clinical investigation 124 (10), 4642-4656, 2014 | 552 | 2014 |
Inflammation and mechanical stretch promote aortic stiffening in hypertension through activation of p38 mitogen-activated protein kinase J Wu, SR Thabet, A Kirabo, DW Trott, MA Saleh, L Xiao, MS Madhur, ... Circulation research 114 (4), 616-625, 2014 | 258 | 2014 |
Oligoclonal CD8+ T Cells Play a Critical Role in the Development of Hypertension DW Trott, SR Thabet, A Kirabo, MA Saleh, H Itani, AE Norlander, J Wu, ... Hypertension 64 (5), 1108-1115, 2014 | 253 | 2014 |
The immune system in hypertension DW Trott, DG Harrison Advances in physiology education 38 (1), 20-24, 2014 | 151 | 2014 |
Dietary rapamycin supplementation reverses age‐related vascular dysfunction and oxidative stress, while modulating nutrient‐sensing, cell cycle, and senescence pathways LA Lesniewski, DR Seals, AE Walker, GD Henson, MW Blimline, DW Trott, ... Aging cell 16 (1), 17-26, 2017 | 148 | 2017 |
Exercise training reverses age-related decrements in endothelium-dependent dilation in skeletal muscle feed arteries DW Trott, F Gunduz, MH Laughlin, CR Woodman Journal of Applied Physiology 106 (6), 1925-1934, 2009 | 95 | 2009 |
Senolytic drugs, dasatinib and quercetin, attenuate adipose tissue inflammation, and ameliorate metabolic function in old age MT Islam, E Tuday, S Allen, J Kim, DW Trott, WL Holland, AJ Donato, ... Aging Cell 22 (2), e13767, 2023 | 81 | 2023 |
NAD (P) H oxidase-derived reactive oxygen species contribute to age-related impairments of endothelium-dependent dilation in rat soleus feed arteries DW Trott, JW Seawright, MJ Luttrell, CR Woodman Journal of Applied Physiology 110 (5), 1171-1180, 2011 | 65 | 2011 |
Age-related arterial immune cell infiltration in mice is attenuated by caloric restriction or voluntary exercise DW Trott, GD Henson, MHT Ho, SA Allison, LA Lesniewski, AJ Donato Experimental gerontology 109, 99-107, 2018 | 32 | 2018 |
Induced Trf2 deletion leads to aging vascular phenotype in mice associated with arterial telomere uncapping, senescence signaling, and oxidative stress RG Morgan, AE Walker, DW Trott, DR Machin, GD Henson, KD Reihl, ... Journal of molecular and cellular cardiology 127, 74-82, 2019 | 30 | 2019 |
Short-term increases in intraluminal pressure reverse age-related decrements in endothelium-dependent dilation in soleus muscle feed arteries CR Woodman, DW Trott, MH Laughlin Journal of Applied Physiology 103 (4), 1172-1179, 2007 | 25 | 2007 |
Inflammation as a mediator of arterial ageing DW Trott, PJ Fadel Experimental physiology 104 (10), 1455-1471, 2019 | 22 | 2019 |
Aging impairs PI3K/Akt signaling and NO-mediated dilation in soleus muscle feed arteries DW Trott, MJ Luttrell, JW Seawright, CR Woodman European journal of applied physiology 113, 2039-2046, 2013 | 22 | 2013 |
T lymphocyte depletion ameliorates age-related metabolic impairments in mice DW Trott, MT Islam, DJ Buckley, AJ Donato, T Dutson, ES Sorensen, J Cai, ... Geroscience 43 (3), 1331-1347, 2021 | 19 | 2021 |
T cells mediate cell non‐autonomous arterial ageing in mice DW Trott, DR Machin, TTT Phuong, ALO Adeyemo, SI Bloom, ... The Journal of physiology 599 (16), 3973-3991, 2021 | 14 | 2021 |
Glycocalyx-targeted therapy ameliorates age-related arterial dysfunction DR Machin, DW Trott, VR Gogulamudi, MT Islam, SI Bloom, H Vink, ... Geroscience 45 (4), 2351-2365, 2023 | 12 | 2023 |
Augmented T-cell mitochondrial reactive oxygen species in adults with major depressive disorder AK Grotle, AM Darling, EF Saunders, PJ Fadel, DW Trott, JL Greaney American Journal of Physiology-Heart and Circulatory Physiology 322 (4 …, 2022 | 12 | 2022 |
Selected life-extending interventions reduce arterial CXCL10 and macrophage colony-stimulating factor in aged mouse arteries DW Trott, LA Lesniewski, AJ Donato Cytokine 96, 102-106, 2017 | 12 | 2017 |
Immunomodulation in age‐related disorders and nanotechnology interventions U Chintapula, T Chikate, D Sahoo, A Kieu, ID Guerrero Rodriguez, ... Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology 15 (1 …, 2023 | 11 | 2023 |
P2X7-Mediated Antigen-Independent Activation of CD8+ T Cells Promotes Salt-Sensitive Hypertension LN Benson, KS Deck, CJ Mora, Y Guo, TM Rafferty, LX Li, L Huang, ... Hypertension 81 (3), 530-540, 2024 | 4 | 2024 |