| Guidelines for the use and interpretation of assays for monitoring autophagy DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 10754 | 2021 |
| Regulation of the mammalian heat shock factor 1 S Dayalan Naidu, AT Dinkova‐Kostova The FEBS journal 284 (11), 1606-1627, 2017 | 171 | 2017 |
| Transcription factors Hsf1 and Nrf2 engage in crosstalk for cytoprotection SD Naidu, RV Kostov, AT Dinkova-Kostova Trends in pharmacological sciences 36 (1), 6-14, 2015 | 138 | 2015 |
| KEAP1-modifying small molecule reveals muted NRF2 signaling responses in neural stem cells from Huntington's disease patients L Quinti, S Dayalan Naidu, U Träger, X Chen, K Kegel-Gleason, D Llères, ... Proceedings of the National Academy of Sciences 114 (23), E4676-E4685, 2017 | 122 | 2017 |
| KEAP1 inhibition is neuroprotective and suppresses the development of epilepsy T Shekh-Ahmad, R Eckel, S Dayalan Naidu, M Higgins, M Yamamoto, ... Brain 141 (5), 1390-1403, 2018 | 108 | 2018 |
| KEAP1, a cysteine-based sensor and a drug target for the prevention and treatment of chronic disease S Dayalan Naidu, AT Dinkova-Kostova Open biology 10 (6), 200105, 2020 | 83 | 2020 |
| SIRT2-and NRF2-targeting thiazole-containing compound with therapeutic activity in Huntington's disease models L Quinti, M Casale, S Moniot, TF Pais, MJ Van Kanegan, LS Kaltenbach, ... Cell chemical biology 23 (7), 849-861, 2016 | 83 | 2016 |
| Heat shock factor 1 is a substrate for p38 mitogen-activated protein kinases S Dayalan Naidu, C Sutherland, Y Zhang, A Risco, L de la Vega, ... Molecular and cellular biology 36 (18), 2403-2417, 2016 | 81 | 2016 |
| Activation of Nrf2 signaling augments vesicular stomatitis virus oncolysis via autophagy-driven suppression of antiviral immunity D Olagnier, RR Lababidi, SB Hadj, A Sze, Y Liu, SD Naidu, M Ferrari, ... Molecular Therapy 25 (8), 1900-1916, 2017 | 78 | 2017 |
| C151 in KEAP1 is the main cysteine sensor for the cyanoenone class of NRF2 activators, irrespective of molecular size or shape S Dayalan Naidu, A Muramatsu, R Saito, S Asami, T Honda, T Hosoya, ... Scientific reports 8 (1), 8037, 2018 | 68 | 2018 |
| Nrf2 activation reprograms macrophage intermediary metabolism and suppresses the type I interferon response DG Ryan, EV Knatko, AM Casey, JL Hukelmann, SD Naidu, AJ Brenes, ... Iscience 25 (2), 2022 | 52 | 2022 |
| Phenethyl isothiocyanate, a dual activator of transcription factors NRF2 and HSF1 S Dayalan Naidu, T Suzuki, M Yamamoto, JW Fahey, ... Molecular nutrition & food research 62 (18), 1700908, 2018 | 51 | 2018 |
| Transcription factors NRF2 and HSF1 have opposing functions in autophagy S Dayalan Naidu, D Dikovskaya, E Gaurilcikaite, EV Knatko, ZR Healy, ... Scientific reports 7 (1), 11023, 2017 | 36 | 2017 |
| Sulphoxythiocarbamates modify cysteine residues in HSP90 causing degradation of client proteins and inhibition of cancer cell proliferation Y Zhang, S Dayalan Naidu, K Samarasinghe, GC Van Hecke, A Pheely, ... British journal of cancer 110 (1), 71-82, 2014 | 32 | 2014 |
| Downregulation of Keap1 confers features of a fasted metabolic state EV Knatko, MH Tatham, Y Zhang, C Castro, M Higgins, SD Naidu, ... IScience 23 (10), 2020 | 23 | 2020 |
| Phenyl bis-sulfonamide Keap1-Nrf2 protein–protein interaction inhibitors with an alternative binding mode N Georgakopoulos, S Talapatra, D Dikovskaya, S Dayalan Naidu, ... Journal of Medicinal Chemistry 65 (10), 7380-7398, 2022 | 18 | 2022 |
| The cell-permeable derivative of the immunoregulatory metabolite itaconate, 4-octyl itaconate, is anti-fibrotic in systemic sclerosis J Henderson, S Dayalan Naidu, AT Dinkova-Kostova, S Przyborski, ... Cells 10 (8), 2053, 2021 | 14 | 2021 |
| Omaveloxolone (SkyclarysTM) for patients with Friedreich’s ataxia SD Naidu, AT Dinkova-Kostova Trends in Pharmacological Sciences, 2023 | 12 | 2023 |
| The isoquinoline PRL-295 increases the thermostability of Keap1 and disrupts its interaction with Nrf2 SD Naidu, T Suzuki, D Dikovskaya, EV Knatko, M Higgins, M Sato, ... Iscience 25 (1), 2022 | 12 | 2022 |
| The synthetic triterpenoids CDDO-TFEA and CDDO-Me, but not CDDO, promote nuclear exclusion of BACH1 impairing its activity L Casares, R Moreno, KX Ali, M Higgins, SD Naidu, G Neill, L Cassin, ... Redox Biology 51, 102291, 2022 | 11 | 2022 |
