Improved LbCas12a variants with altered PAM specificities further broaden the genome targeting range of Cas12a nucleases E Tóth, É Varga, PI Kulcsár, V Kocsis-Jutka, SL Krausz, A Nyeste, ... Nucleic acids research 48 (7), 3722-3733, 2020 | 93 | 2020 |
Mb-and FnCpf1 nucleases are active in mammalian cells: activities and PAM preferences of four wild-type Cpf1 nucleases and of their altered PAM specificity variants E Tóth, BC Czene, PI Kulcsár, SL Krausz, A Tálas, A Nyeste, É Varga, ... Nucleic acids research 46 (19), 10272-10285, 2018 | 64 | 2018 |
A convenient method to pre-screen candidate guide RNAs for CRISPR/Cas9 gene editing by NHEJ-mediated integration of a ‘self-cleaving’GFP-expression plasmid A Tálas, PI Kulcsár, N Weinhardt, A Borsy, E Tóth, K Szebényi, SL Krausz, ... DNA Research 24 (6), 609-621, 2017 | 27 | 2017 |
PEAR, a flexible fluorescent reporter for the identification and enrichment of successfully prime edited cells DA Simon, A Tálas, PI Kulcsár, Z Biczók, SL Krausz, G Várady, E Welker Elife 11, e69504, 2022 | 25 | 2022 |
SuperFi-Cas9 exhibits remarkable fidelity but severely reduced activity yet works effectively with ABE8e PI Kulcsár, A Tálas, Z Ligeti, SL Krausz, E Welker Nature Communications 13 (1), 6858, 2022 | 17 | 2022 |
BEAR reveals that increased fidelity variants can successfully reduce the mismatch tolerance of adenine but not cytosine base editors A Tálas, DA Simon, PI Kulcsár, É Varga, SL Krausz, E Welker Nature communications 12 (1), 6353, 2021 | 16 | 2021 |
The G127V variant of the prion protein interferes with dimer formation in vitro but not in cellulo SB Sangeetham, AD Engelke, E Fodor, SL Krausz, J Tatzelt, E Welker Scientific Reports 11 (1), 3116, 2021 | 3 | 2021 |
Position-dependent sequence motif preferences of SpCas9 are largely determined by scaffold-complementary spacer motifs K Huszár, Z Welker, Z Györgypál, E Tóth, Z Ligeti, PI Kulcsár, J Dancsó, ... Nucleic Acids Research, gkad323, 2023 | 2 | 2023 |
A cleavage rule for selection of increased-fidelity SpCas9 variants with high efficiency and no detectable off-targets PI Kulcsár, A Tálas, Z Ligeti, E Tóth, Z Rakvács, Z Bartos, SL Krausz, ... Nature Communications 14 (1), 5746, 2023 | 1 | 2023 |