| High-resolution mapping of the spatial organization of a bacterial chromosome TBK Le, MV Imakaev, LA Mirny, MT Laub Science 342 (6159), 731-734, 2013 | 652 | 2013 |
| Bacterial chromosome organization and segregation A Badrinarayanan, TBK Le, MT Laub Annual review of cell and developmental biology 31 (1), 171-199, 2015 | 302 | 2015 |
| Bacillus subtilis SMC complexes juxtapose chromosome arms as they travel from origin to terminus X Wang, HB Brandão, TBK Le, MT Laub, DZ Rudner Science 355 (6324), 524-527, 2017 | 283 | 2017 |
| Condensin promotes the juxtaposition of DNA flanking its loading site in Bacillus subtilis X Wang, TBK Le, BR Lajoie, J Dekker, MT Laub, DZ Rudner Genes & development 29 (15), 1661-1675, 2015 | 233 | 2015 |
| Transcription rate and transcript length drive formation of chromosomal interaction domain boundaries TBK Le, MT Laub The EMBO journal 35 (14), 1582-1595, 2016 | 137 | 2016 |
| SMC Progressively Aligns Chromosomal Arms in Caulobacter crescentus but Is Antagonized by Convergent Transcription NT Tran, MT Laub, TBK Le Cell Reports 20 (9), 2057-2071, 2017 | 131 | 2017 |
| A crystal structure of the bifunctional antibiotic simocyclinone D8, bound to DNA gyrase MJ Edwards, RH Flatman, LA Mitchenall, CEM Stevenson, TBK Le, ... Science 326 (5958), 1415-1418, 2009 | 113 | 2009 |
| Bacterial chromosome segregation by the ParABS system ASB Jalal, TBK Le Open biology 10 (6), 200097, 2020 | 104 | 2020 |
| The crystal structure of the TetR family transcriptional repressor SimR bound to DNA and the role of a flexible N-terminal extension in minor groove binding TBK Le, MA Schumacher, DM Lawson, RG Brennan, MJ Buttner Nucleic acids research 39 (21), 9433-9447, 2011 | 86 | 2011 |
| ParB spreading on DNA requires cytidine triphosphate in vitro ASB Jalal, NT Tran, TBK Le Elife 9, e53515, 2020 | 83 | 2020 |
| Coupling of the biosynthesis and export of the DNA gyrase inhibitor simocyclinone in Streptomyces antibioticus TBK Le, HP Fiedler, CD Den Hengst, SK Ahn, A Maxwell, MJ Buttner Molecular microbiology 72 (6), 1462-1474, 2009 | 55 | 2009 |
| Rapid pairing and resegregation of distant homologous loci enables double-strand break repair in bacteria A Badrinarayanan, TBK Le, MT Laub Journal of Cell Biology 210 (3), 385-400, 2015 | 52 | 2015 |
| Investigation of DNA sequence recognition by a streptomycete MarR family transcriptional regulator through surface plasmon resonance and X-ray crystallography CEM Stevenson, A Assaad, G Chandra, TBK Le, SJ Greive, MJ Bibb, ... Nucleic acids research 41 (14), 7009-7022, 2013 | 50 | 2013 |
| Structures of the TetR-like simocyclinone efflux pump repressor, SimR, and the mechanism of ligand-mediated derepression TBK Le, CEM Stevenson, HP Fiedler, A Maxwell, DM Lawson, MJ Buttner Journal of molecular biology 408 (1), 40-56, 2011 | 46 | 2011 |
| New approaches to understanding the spatial organization of bacterial genomes TBK Le, MT Laub Current opinion in microbiology 22, 15-21, 2014 | 43 | 2014 |
| Permissive zones for the centromere-binding protein ParB on the Caulobacter crescentus chromosome NT Tran, CE Stevenson, NF Som, A Thanapipatsiri, ASB Jalal, TBK Le Nucleic acids research 46 (3), 1196-1209, 2018 | 40 | 2018 |
| A CTP-dependent gating mechanism enables ParB spreading on DNA ASB Jalal, NT Tran, CEM Stevenson, A Chimthanawala, ... Elife 10, e69676, 2021 | 37* | 2021 |
| Spatial rearrangement of the Streptomyces venezuelae linear chromosome during sporogenic development MJ Szafran, T Małecki, A Strzałka, K Pawlikiewicz, J Duława, A Zarek, ... Nature Communications 12 (1), 1-15, 2021 | 36 | 2021 |
| The MerR-like protein BldC binds DNA direct repeats as cooperative multimers to regulate Streptomyces development MA Schumacher, CD den Hengst, MJ Bush, TBK Le, NT Tran, G Chandra, ... Nature communications 9 (1), 1139, 2018 | 35 | 2018 |
| Diversification of DNA-binding specificity by permissive and specificity-switching mutations in the ParB/Noc protein family ASB Jalal, NT Tran, CE Stevenson, EW Chan, R Lo, X Tan, A Noy, ... Cell reports 32 (3), 107928, 2020 | 32 | 2020 |
Michael LaubProfessor of Biology, MIT and Howard Hughes Medical InstituteVerified email at mit.edu
