Tung BK Le
Tung BK Le
Group Leader-Associate Professor, John Innes Centre, UK
Verified email at - Homepage
Cited by
Cited by
High-resolution mapping of the spatial organization of a bacterial chromosome
TBK Le, MV Imakaev, LA Mirny, MT Laub
Science 342 (6159), 731-734, 2013
Bacterial chromosome organization and segregation
A Badrinarayanan, TBK Le, MT Laub
Annual review of cell and developmental biology 31, 171-199, 2015
Bacillus subtilis SMC complexes juxtapose chromosome arms as they travel from origin to terminus
X Wang, HB Brandão, TBK Le, MT Laub, DZ Rudner
Science 355 (6324), 524-527, 2017
Condensin promotes the juxtaposition of DNA flanking its loading site in Bacillus subtilis
X Wang, TBK Le, BR Lajoie, J Dekker, MT Laub, DZ Rudner
Genes & development 29 (15), 1661-1675, 2015
Transcription rate and transcript length drive formation of chromosomal interaction domain boundaries
TBK Le, MT Laub
The EMBO journal 35 (14), 1582-1595, 2016
SMC Progressively Aligns Chromosomal Arms in Caulobacter crescentus but Is Antagonized by Convergent Transcription
NT Tran, MT Laub, TBK Le
Cell Reports 20 (9), 2057-2071, 2017
A crystal structure of the bifunctional antibiotic simocyclinone D8, bound to DNA gyrase
MJ Edwards, RH Flatman, LA Mitchenall, CEM Stevenson, TBK Le, ...
Science 326 (5958), 1415-1418, 2009
Bacterial chromosome segregation by the ParABS system
ASB Jalal, TBK Le
Open biology 10 (6), 200097, 2020
The crystal structure of the TetR family transcriptional repressor SimR bound to DNA and the role of a flexible N-terminal extension in minor groove binding
TBK Le, MA Schumacher, DM Lawson, RG Brennan, MJ Buttner
Nucleic acids research 39 (21), 9433-9447, 2011
ParB spreading on DNA requires cytidine triphosphate in vitro
ASB Jalal, NT Tran, TBK Le
Elife 9, e53515, 2020
Coupling of the biosynthesis and export of the DNA gyrase inhibitor simocyclinone in Streptomyces antibioticus
TBK Le, HP Fiedler, CD Den Hengst, SK Ahn, A Maxwell, MJ Buttner
Molecular microbiology 72 (6), 1462-1474, 2009
Rapid pairing and resegregation of distant homologous loci enables double-strand break repair in bacteria
A Badrinarayanan, TBK Le, MT Laub
Journal of Cell Biology 210 (3), 385-400, 2015
Investigation of DNA sequence recognition by a streptomycete MarR family transcriptional regulator through surface plasmon resonance and X-ray crystallography
CEM Stevenson, A Assaad, G Chandra, TBK Le, SJ Greive, MJ Bibb, ...
Nucleic acids research 41 (14), 7009-7022, 2013
New approaches to understanding the spatial organization of bacterial genomes
TBK Le, MT Laub
Current opinion in microbiology 22, 15-21, 2014
Structures of the TetR-like simocyclinone efflux pump repressor, SimR, and the mechanism of ligand-mediated derepression
TBK Le, CEM Stevenson, HP Fiedler, A Maxwell, DM Lawson, MJ Buttner
Journal of molecular biology 408 (1), 40-56, 2011
Permissive zones for the centromere-binding protein ParB on the Caulobacter crescentus chromosome
NT Tran, CE Stevenson, NF Som, A Thanapipatsiri, ASB Jalal, TBK Le
Nucleic acids research 46 (3), 1196-1209, 2018
The MerR-like protein BldC binds DNA direct repeats as cooperative multimers to regulate Streptomyces development
MA Schumacher, CD den Hengst, MJ Bush, TBK Le, NT Tran, G Chandra, ...
Nature communications 9 (1), 1139, 2018
A CTP-dependent gating mechanism enables ParB spreading on DNA
ASB Jalal, NT Tran, CEM Stevenson, A Chimthanawala, ...
Elife 10, e69676, 2021
Diversification of DNA-binding specificity by permissive and specificity-switching mutations in the ParB/Noc protein family
ASB Jalal, NT Tran, CE Stevenson, EW Chan, R Lo, X Tan, A Noy, ...
Cell reports 32 (3), 107928, 2020
Spatial rearrangement of the Streptomyces venezuelae linear chromosome during sporogenic development
MJ Szafran, T Małecki, A Strzałka, K Pawlikiewicz, J Duława, A Zarek, ...
Nature Communications 12 (1), 1-15, 2021
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