| The transcription factor STAT6 mediates direct repression of inflammatory enhancers and limits activation of alternatively polarized macrophages Z Czimmerer, B Daniel, A Horvath, D Rückerl, G Nagy, M Kiss, M Peloquin, ... Immunity 48 (1), 75-90. e6, 2018 | 214 | 2018 |
| Macrophage PPARγ, a lipid activated transcription factor controls the growth factor GDF3 and skeletal muscle regeneration T Varga, R Mounier, A Patsalos, P Gogolák, M Peloquin, A Horvath, A Pap, ... Immunity 45 (5), 1038-1051, 2016 | 146 | 2016 |
| The nuclear receptor PPARγ controls progressive macrophage polarization as a ligand-insensitive epigenomic ratchet of transcriptional memory B Daniel, G Nagy, Z Czimmerer, A Horvath, DW Hammers, ... Immunity 49 (4), 615-626. e6, 2018 | 139 | 2018 |
| The active enhancer network operated by liganded RXR supports angiogenic activity in macrophages B Daniel, G Nagy, N Hah, A Horvath, Z Czimmerer, S Poliska, T Gyuris, ... Genes & development 28 (14), 1562-1577, 2014 | 99 | 2014 |
| Research resource: transcriptome profiling of genes regulated by RXR and its permissive and nonpermissive partners in differentiating monocyte-derived dendritic cells L Szeles, S Poliska, G Nagy, I Szatmari, A Szanto, A Pap, M Lindstedt, ... Molecular endocrinology 24 (11), 2218-2231, 2010 | 93 | 2010 |
| The IL-4/STAT6/PPARγ signaling axis is driving the expansion of the RXR heterodimer cistrome, providing complex ligand responsiveness in macrophages B Daniel, G Nagy, A Horvath, Z Czimmerer, I Cuaranta-Monroy, S Poliska, ... Nucleic acids research 46 (9), 4425-4439, 2018 | 57 | 2018 |
| Inducible super-enhancers are organized based on canonical signal-specific transcription factor binding elements D Bojcsuk, G Nagy, BL Balint Nucleic acids research 45 (7), 3693-3706, 2017 | 53 | 2017 |
| Highly efficient differentiation of embryonic stem cells into adipocytes by ascorbic acid I Cuaranta-Monroy, Z Simandi, Z Kolostyak, QM Doan-Xuan, S Poliska, ... Stem Cell Research 13 (1), 88-97, 2014 | 52 | 2014 |
| The IL-4/STAT6 signaling axis establishes a conserved microRNA signature in human and mouse macrophages regulating cell survival via miR-342-3p Z Czimmerer, T Varga, M Kiss, CO Vázquez, QM Doan-Xuan, D Rückerl, ... Genome medicine 8, 1-22, 2016 | 46 | 2016 |
| The transcription factor EGR2 is the molecular linchpin connecting STAT6 activation to the late, stable epigenomic program of alternative macrophage polarization B Daniel, Z Czimmerer, L Halasz, P Boto, Z Kolostyak, S Poliska, ... Genes & development 34 (21-22), 1474-1492, 2020 | 40 | 2020 |
| A growth factor–expressing macrophage subpopulation orchestrates regenerative inflammation via GDF-15 A Patsalos, L Halasz, MA Medina-Serpas, WK Berger, B Daniel, ... Journal of Experimental Medicine 219 (1), e20210420, 2021 | 37 | 2021 |
| The intriguing complexities of mammalian gene regulation: how to link enhancers to regulated genes. Are we there yet? B Daniel, G Nagy, L Nagy FEBS letters 588 (15), 2379-2391, 2014 | 36 | 2014 |
| Motif oriented high-resolution analysis of ChIP-seq data reveals the topological order of CTCF and cohesin proteins on DNA G Nagy, E Czipa, L Steiner, T Nagy, S Pongor, L Nagy, E Barta BMC genomics 17, 1-9, 2016 | 32 | 2016 |
| Agonist binding directs dynamic competition among nuclear receptors for heterodimerization with retinoid X receptor L Fadel, B Rehó, J Volkó, D Bojcsuk, Z Kolostyák, G Nagy, G Müller, ... Journal of Biological Chemistry 295 (29), 10045-10061, 2020 | 31 | 2020 |
| Specific enhancer selection by IRF3, IRF5 and IRF9 is determined by ISRE half-sites, 5′ and 3′ flanking bases, collaborating transcription factors and the chromatin … M Csumita, A Csermely, A Horvath, G Nagy, F Monori, L Göczi, HA Orbea, ... Nucleic acids research 48 (2), 589-604, 2020 | 30 | 2020 |
| Retinoid X receptor suppresses a metastasis-promoting transcriptional program in myeloid cells via a ligand-insensitive mechanism M Kiss, Z Czimmerer, G Nagy, P Bieniasz-Krzywiec, M Ehling, A Pap, ... Proceedings of the National Academy of Sciences 114 (40), 10725-10730, 2017 | 26 | 2017 |
| The BACH1–HMOX1 regulatory axis is indispensable for proper macrophage subtype specification and skeletal muscle regeneration A Patsalos, P Tzerpos, L Halasz, G Nagy, A Pap, N Giannakis, K Lyroni, ... The Journal of Immunology 203 (6), 1532-1547, 2019 | 23 | 2019 |
| Extensive and functional overlap of the STAT6 and RXR cistromes in the active enhancer repertoire of human CD14+ monocyte derived differentiating macrophages Z Czimmerer, ZS Nagy, G Nagy, A Horvath, T Silye-Cseh, A Kriston, ... Molecular and Cellular Endocrinology 471, 63-74, 2018 | 18 | 2018 |
| A novel method to predict regulatory regions based on histone mark landscapes in macrophages G Nagy, B Dániel, D Jónás, L Nagy, E Barta Immunobiology 218 (11), 1416-1427, 2013 | 18 | 2013 |
| Motif grammar: The basis of the language of gene expression G Nagy, L Nagy Computational and Structural Biotechnology Journal 18, 2026-2032, 2020 | 14 | 2020 |
Laszlo NagyProfessor and Co-Director, Johns Hopkins University School of Medicine and University of DebrecenVerified email at jhmi.edu
