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Modelling of the blood–brain barrier in drug discovery and development
R Cecchelli, V Berezowski, S Lundquist, M Culot, M Renftel, MP Dehouck, ...
Nature reviews Drug discovery 6 (8), 650-661, 2007
An easier, reproducible, and mass‐production method to study the blood–brain barrier in vitro
MP Dehouck, S Méresse, P Delorme, JC Fruchart, R Cecchelli
Journal of neurochemistry 54 (5), 1798-1801, 1990
A new function for the LDL receptor: transcytosis of LDL across the blood–brain barrier
B Dehouck, L Fenart, MP Dehouck, A Pierce, G Torpier, R Cecchelli
The Journal of cell biology 138 (4), 877-889, 1997
In vitro models for the blood–brain barrier
P Garberg, M Ball, N Borg, R Cecchelli, L Fenart, RD Hurst, T Lindmark, ...
Toxicology in vitro 19 (3), 299-334, 2005
In vitro models of the blood–brain barrier: an overview of commonly used brain endothelial cell culture models and guidelines for their use
HC Helms, NJ Abbott, M Burek, R Cecchelli, PO Couraud, MA Deli, ...
Journal of Cerebral Blood Flow & Metabolism 36 (5), 862-890, 2016
In vitro model for evaluating drug transport across the blood–brain barrier
R Cecchelli, B Dehouck, L Descamps, L Fenart, V Buée-Scherrer, ...
Advanced drug delivery reviews 36 (2-3), 165-178, 1999
Receptor-mediated transcytosis of lactoferrin through the blood-brain barrier
C Fillebeen, L Descamps, MP Dehouck, L Fenart, M Benaı̈ssa, G Spik, ...
Journal of Biological Chemistry 274 (11), 7011-7017, 1999
Drug transfer across the blood‐brain barrier: correlation between in vitro and in vivo models
MP Dehouck, P Jolliet‐Riant, F Brée, JC Fruchart, R Cecchelli, ...
Journal of neurochemistry 58 (5), 1790-1797, 1992
Peroxisome proliferator-activated receptor-α activation as a mechanism of preventive neuroprotection induced by chronic fenofibrate treatment
D Deplanque, P Gelé, O Pétrault, I Six, C Furman, M Bouly, S Nion, ...
Journal of Neuroscience 23 (15), 6264-6271, 2003
Indirect evidence that drug brain targeting using polysorbate 80-coated polybutylcyanoacrylate nanoparticles is related to toxicity
JC Olivier, L Fenart, R Chauvet, C Pariat, R Cecchelli, W Couet
Pharmaceutical research 16 (12), 1836-1842, 1999
Upregulation of the low density lipoprotein receptor at the blood-brain barrier: intercommunications between brain capillary endothelial cells and astrocytes
B Dehouck, MP Dehouck, JC Fruchart, R Cecchelli
Review & Expositor 84 (1), 465-473, 1987
Bovine brain endothelial cells express tight junctions and monoamine oxidase activity in long‐term culture
S Méresse, MP Dehouck, P Delorme, M Bensaïd, JP Tauber, C Delbart, ...
Journal of neurochemistry 53 (5), 1363-1371, 1989
Evaluation of effect of charge and lipid coating on ability of 60-nm nanoparticles to cross an in vitro model of the blood-brain barrier
L Fenart, A Casanova, B Dehouck, C Duhem, S Slupek, R Cecchelli, ...
Journal of Pharmacology and Experimental Therapeutics 291 (3), 1017-1022, 1999
High transcytosis of melanotransferrin (P97) across the blood–brain barrier
M Demeule, J Poirier, J Jodoin, Y Bertrand, RR Desrosiers, C Dagenais, ...
Journal of neurochemistry 83 (4), 924-933, 2002
VEGF-induced BBB permeability is associated with an MMP-9 activity increase in cerebral ischemia: both effects decreased by Ang-1
S Valable, J Montaner, A Bellail, V Berezowski, J Brillault, R Cecchelli, ...
Journal of Cerebral Blood Flow & Metabolism 25 (11), 1491-1504, 2005
Ca2+ regulation of connexin 43 hemichannels in C6 glioma and glial cells
E De Vuyst, N Wang, E Decrock, M De Bock, M Vinken, M Van Moorhem, ...
Cell calcium 46 (3), 176-187, 2009
A stable and reproducible human blood-brain barrier model derived from hematopoietic stem cells
R Cecchelli, S Aday, E Sevin, C Almeida, M Culot, L Dehouck, C Coisne, ...
PloS one 9 (6), e99733, 2014
Prediction of drug transport through the blood-brain barrier in vivo: a comparison between two in vitro cell models
S Lundquist, M Renftel, J Brillault, L Fenart, R Cecchelli, MP Dehouck
Pharmaceutical research 19 (7), 976-981, 2002
Differential roles for endothelial ICAM-1, ICAM-2, and VCAM-1 in shear-resistant T cell arrest, polarization, and directed crawling on blood–brain barrier endothelium
O Steiner, C Coisne, R Cecchelli, R Boscacci, U Deutsch, B Engelhardt, ...
The Journal of Immunology 185 (8), 4846-4855, 2010
Tissue-type plasminogen activator crosses the intact blood-brain barrier by low-density lipoprotein receptor–related protein-mediated transcytosis
K Benchenane, V Berezowski, C Ali, M Fernández-Monreal, ...
Circulation 111 (17), 2241-2249, 2005
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