Követés
Raymond Evers
Raymond Evers
Janssen Pharmaceuticals
E-mail megerősítve itt: its.jnj.com
Cím
Hivatkozott rá
Hivatkozott rá
Év
Membrane transporters in drug development
Nature reviews Drug discovery 9 (3), 215-236, 2010
34812010
A family of drug transporters: the multidrug resistance-associated proteins
P Borst, R Evers, M Kool, J Wijnholds
Journal of the National Cancer Institute 92 (16), 1295-1302, 2000
23472000
The multidrug resistance protein family
P Borst, R Evers, M Kool, J Wijnholds
Biochimica et Biophysica Acta (BBA)-Biomembranes 1461 (2), 347-357, 1999
8871999
Drug export activity of the human canalicular multispecific organic anion transporter in polarized kidney MDCK cells expressing cMOAT (MRP2) cDNA.
R Evers, M Kool, L van Deemter, H Janssen, J Calafat, LC Oomen, ...
The Journal of clinical investigation 101 (7), 1310-1319, 1998
5631998
Increased sensitivity to anticancer drugs and decreased inflammatory response in mice lacking the multidrug resistance-associated protein
J Wijnholds, R Evers, MR van Leusden, CAAM Mol, GJR Zaman, U Mayer, ...
Nature medicine 3 (11), 1275-1279, 1997
5371997
Functional multidrug resistance protein (MRP1) lacking the N-terminal transmembrane domain
E Bakos, R Evers, G Szakács, GE Tusnády, E Welker, K Szabó, ...
Journal of Biological Chemistry 273 (48), 32167-32175, 1998
4101998
Interactions of the human multidrug resistance proteins MRP1 and MRP2 with organic anions
É Bakos, R Evers, E Sinkó, A Váradi, P Borst, B Sarkadi
Molecular pharmacology 57 (4), 760-768, 2000
3952000
Basolateral localization and export activity of the human multidrug resistance-associated protein in polarized pig kidney cells.
R Evers, GJ Zaman, L van Deemter, H Jansen, J Calafat, LC Oomen, ...
The Journal of clinical investigation 97 (5), 1211-1218, 1996
3381996
Expression profiles of 50 xenobiotic transporter genes in humans and pre-clinical species: a resource for investigations into drug disposition
K Bleasby, JC Castle, CJ Roberts, C Cheng, WJ Bailey, JF Sina, ...
Xenobiotica 36 (10-11), 963-988, 2006
3172006
Canalicular multispecific organic anion transporter/multidrug resistance protein 2 mediates low-affinity transport of reduced glutathione
CC PAULUSMA, MA GEER, R EVERS, M HEIJN, R OTTENHOFF, ...
Biochemical Journal 338 (2), 393-401, 1999
3081999
Species differences in drug transporters and implications for translating preclinical findings to humans
X Chu, K Bleasby, R Evers
Expert opinion on drug metabolism & toxicology 9 (3), 237-252, 2013
2972013
Vinblastine and sulfinpyrazone export by the multidrug resistance protein MRP2 is associated with glutathione export
R Evers, M De Haas, R Sparidans, J Beijnen, PR Wielinga, J Lankelma, ...
British journal of cancer 83 (3), 375-383, 2000
2772000
Inhibitory effect of the reversal agents V-104, GF120918 and Pluronic L61 on MDR1 Pgp-, MRP1-and MRP2-mediated transport
R Evers, M Kool, AJ Smith, L Van Deemter, M De Haas, P Borst
British journal of cancer 83 (3), 366-374, 2000
2772000
In Vitro Methods to Support Transporter Evaluation in Drug Discovery and Development
KLR Brouwer, D Keppler, KA Hoffmaster, DAJ Bow, Y Cheng, Y Lai, ...
Clinical Pharmacology & Therapeutics 94 (1), 95-112, 2013
2692013
The human multidrug resistance-associated protein functionally complements the yeast cadmium resistance factor 1.
R ToMMASINI, R Evers, E Vogt, C Mornet, GJ Zaman, AH Schinkel, ...
Proceedings of the National Academy of Sciences 93 (13), 6743-6748, 1996
2191996
Interindividual variability in hepatic organic anion-transporting polypeptides and P-glycoprotein (ABCB1) protein expression: quantification by liquid chromatography tandem …
B Prasad, R Evers, A Gupta, CECA Hop, L Salphati, S Shukla, ...
Drug Metabolism and Disposition 42 (1), 78-88, 2014
2032014
Transport of the dipeptidyl peptidase-4 inhibitor sitagliptin by human organic anion transporter 3, organic anion transporting polypeptide 4C1, and multidrug resistance P …
XY Chu, K Bleasby, J Yabut, X Cai, GH Chan, MJ Hafey, S Xu, ...
Journal of Pharmacology and Experimental Therapeutics 321 (2), 673-683, 2007
2032007
Interspecies variability in expression of hepatobiliary transporters across human, dog, monkey, and rat as determined by quantitative proteomics
L Wang, B Prasad, L Salphati, X Chu, A Gupta, CECA Hop, R Evers, ...
Drug Metabolism and Disposition 43 (3), 367-374, 2015
1932015
In vitro and in vivo induction of cytochrome p450: a survey of the current practices and recommendations: a pharmaceutical research and manufacturers of america perspective
V Chu, HJ Einolf, R Evers, G Kumar, D Moore, S Ripp, J Silva, V Sinha, ...
Drug Metabolism and Disposition 37 (7), 1339-1354, 2009
1822009
The human multidrug resistance protein MRP1 translocates sphingolipid analogs across the plasma membrane
RJ Raggers, A Helvoort, R Evers, G Meer
Journal of cell science 112 (3), 415-422, 1999
1821999
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