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Bhushan Nagar
Bhushan Nagar
Professor, Department of Biochemistry, McGill University
Verified email at mcgill.ca - Homepage
Title
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Cited by
Year
Multiple BCR-ABL kinase domain mutations confer polyclonal resistance to the tyrosine kinase inhibitor imatinib (STI571) in chronic phase and blast crisis chronic myeloid leukemia
NP Shah, JM Nicoll, B Nagar, ME Gorre, RL Paquette, J Kuriyan, ...
Cancer cell 2 (2), 117-125, 2002
20712002
Crystal structures of the kinase domain of c-Abl in complex with the small molecule inhibitors PD173955 and imatinib (STI-571)
B Nagar, WG Bornmann, P Pellicena, T Schindler, DR Veach, WT Miller, ...
Cancer research 62 (15), 4236-4243, 2002
13062002
Structural basis for the autoinhibition of c-Abl tyrosine kinase
B Nagar, O Hantschel, MA Young, K Scheffzek, D Veach, W Bornmann, ...
Cell 112 (6), 859-871, 2003
10392003
Structural basis of calcium-induced E-cadherin rigidification and dimerization
B Nagar, M Overduin, M Ikura, JM Rini
Nature 380 (6572), 360-364, 1996
9001996
Structural basis for 5′-nucleotide base-specific recognition of guide RNA by human AGO2
F Frank, N Sonenberg, B Nagar
Nature 465 (7299), 818-822, 2010
7392010
A myristoyl/phosphotyrosine switch regulates c-Abl
O Hantschel, B Nagar, S Guettler, J Kretzschmar, K Dorey, J Kuriyan, ...
Cell 112 (6), 845-857, 2003
5772003
Structure of parkin reveals mechanisms for ubiquitin ligase activation
JF Trempe, V Sauvé, K Grenier, M Seirafi, MY Tang, M Ménade, ...
Science 340 (6139), 1451-1455, 2013
5412013
Structural evidence for feedback activation by Ras· GTP of the Ras-specific nucleotide exchange factor SOS
SM Margarit, H Sondermann, BE Hall, B Nagar, A Hoelz, M Pirruccello, ...
Cell 112 (5), 685-695, 2003
5372003
miRNA-mediated deadenylation is orchestrated by GW182 through two conserved motifs that interact with CCR4–NOT
MR Fabian, MK Cieplak, F Frank, M Morita, J Green, T Srikumar, B Nagar, ...
Nature structural & molecular biology 18 (11), 1211-1217, 2011
4042011
Crystallization and preliminary X-ray diffraction analysis of the MIF4G domain of DAP5
F Frank, G Virgili, N Sonenberg, B Nagar
Acta Crystallographica Section F: Structural Biology and Crystallization …, 2010
3042010
Structural basis for the recruitment of the human CCR4–NOT deadenylase complex by tristetraprolin
MR Fabian, F Frank, C Rouya, N Siddiqui, WS Lai, A Karetnikov, ...
Nature structural & molecular biology 20 (6), 735-739, 2013
2792013
c-Src binds to the cancer drug imatinib with an inactive Abl/c-Kit conformation and a distributed thermodynamic penalty
MA Seeliger, B Nagar, F Frank, X Cao, MN Henderson, J Kuriyan
Structure 15 (3), 299-311, 2007
2612007
X-ray crystal structure of C3d: a C3 fragment and ligand for complement receptor 2
B Nagar, RG Jones, RJ Diefenbach, DE Isenman, JM Rini
Science 280 (5367), 1277-1281, 1998
2601998
Organization of the SH3-SH2 unit in active and inactive forms of the c-Abl tyrosine kinase
B Nagar, O Hantschel, M Seeliger, JM Davies, WI Weis, G Superti-Furga, ...
Molecular cell 21 (6), 787-798, 2006
2552006
Structural basis for viral 5′-PPP-RNA recognition by human IFIT proteins
YM Abbas, A Pichlmair, MW Górna, G Superti-Furga, B Nagar
Nature 494 (7435), 60-64, 2013
2532013
Characterization of potent inhibitors of the Bcr-Abl and the c-kit receptor tyrosine kinases
D Wisniewski, CL Lambek, C Liu, A Strife, DR Veach, B Nagar, MA Young, ...
Cancer research 62 (15), 4244-4255, 2002
2132002
Crystal structure of the bb′ domains of the protein disulfide isomerase ERp57
G Kozlov, P Maattanen, JD Schrag, S Pollock, M Cygler, B Nagar, ...
Structure 14 (8), 1331-1339, 2006
1812006
An autoinhibited structure of α-catenin and its implications for vinculin recruitment to adherens junctions
N Ishiyama, N Tanaka, K Abe, YJ Yang, YM Abbas, M Umitsu, B Nagar, ...
Journal of Biological Chemistry 288 (22), 15913-15925, 2013
1402013
Arabidopsis Argonaute MID domains use their nucleotide specificity loop to sort small RNAs
F Frank, J Hauver, N Sonenberg, B Nagar
The EMBO journal 31 (17), 3588-3595, 2012
1162012
DAP5 associates with eIF2β and eIF4AI to promote Internal Ribosome Entry Site driven translation
N Liberman, V Gandin, YV Svitkin, M David, G Virgili, M Jaramillo, ...
Nucleic acids research 43 (7), 3764-3775, 2015
1142015
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