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Hu Chen
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Mechanical activation of vinculin binding to talin locks talin in an unfolded conformation
M Yao, BT Goult, H Chen, P Cong, MP Sheetz, J Yan
Scientific Reports 4, 4610, 2014
4062014
A divalent switch drives H-NS/DNA-binding conformations between stiffening and bridging modes
Y Liu, H Chen, LJ Kenney, J Yan
Genes & development 24 (4), 339-344, 2010
2792010
Improved high-force magnetic tweezers for stretching and refolding of proteins and short DNA
H Chen, H Fu, X Zhu, P Cong, F Nakamura, J Yan
Biophys J 100 (2), 517, 2011
1912011
Dynamics of Equilibrium Folding and Unfolding Transitions of Titin Immunoglobulin Domain under Constant Forces
H Chen, G Yuan, RS Winardhi, M Yao, I Popa, JM Fernandez, J Yan
Journal of the American Chemical Society 137 (10), 3540-3546, 2015
1672015
Revealing the competition between peeled ssDNA, melting bubbles, and S-DNA during DNA overstretching by single-molecule calorimetry
X Zhang, H Chen, S Le, I Rouzina, PS Doyle, J Yan
Proc Natl Acad Sci U S A 110 (10), 3865, 2013
1632013
Two distinct overstretched DNA structures revealed by single-molecule thermodynamics measurements
X Zhang, H Chen, H Fu, PS Doyle, J Yan
Proc Natl Acad Sci U S A 109 (21), 8103-8, 2012
1442012
Two distinct overstretched DNA states
H Fu, H Chen, JF Marko, J Yan
Nucleic Acids Research 38 (16), 5594, 2010
1342010
Transition dynamics and selection of the distinct S-DNA and strand unpeeling modes of double helix overstretching
H Fu, H Chen, X Zhang, Y Qu, JF Marko, J Yan
Nucleic Acids Research 39 (8), 3473-81, 2010
1172010
Mechanotransmission and mechanosensing of human alpha-actinin 1
S Le, X Hu, M Yao, H Chen, M Yu, X Xu, N Nakazawa, FM Margadant, ...
Cell reports 21 (10), 2714-2723, 2017
842017
Elasticity of the transition state leading to an unexpected mechanical stabilization of titin immunoglobulin domains
G Yuan, S Le, M Yao, H Qian, X Zhou, J Yan, H Chen
Angewandte Chemie International Edition 56 (20), 5490-5493, 2017
772017
Differential mechanical stability of filamin A rod segments
H Chen, X Zhu, P Cong, MP Sheetz, F Nakamura, J Yan
Biophys J 101 (5), 1231, 2011
672011
Physical organization of DNA by multiple non-specific DNA-binding modes of integration host factor (IHF)
J Lin, H Chen, P Droge, J Yan
PLoS One 7 (11), e49885, 2012
592012
Mechanical perturbation of filamin A immunoglobulin repeats 20-21 reveals potential non-equilibrium mechanochemical partner binding function
H Chen, S Chandrasekar, MP Sheetz, TP Stossel, F Nakamura, J Yan
Scientific Reports 3, 1642, 2013
542013
Force and ATP hydrolysis dependent regulation of RecA nucleoprotein filament by single-stranded DNA binding protein
H Fu, S Le, H Chen, K Muniyappa, J Yan
Nucleic Acids Research 41 (2), 924-932, 2012
492012
Can electric field induced energy gaps in metallic carbon nanotubes?
X Zhou, H Chen, ZC Ou-Yang
Journal of Physics-Condensed Matter 13 (27), L635-L640, 2001
472001
Structural–elastic determination of the force-dependent transition rate of biomolecules
S Guo, Q Tang, M Yao, H You, S Le, H Chen, J Yan
Chemical science 9 (27), 5871-5882, 2018
452018
Interconversion between three overstretched DNA structures
X Zhang, Y Qu, H Chen, I Rouzina, S Zhang, PS Doyle, J Yan
Journal of the American Chemical Society 136 (45), 16073-16080, 2014
412014
Revisiting the anomalous bending elasticity of sharply bent DNA
P Cong, L Dai, H Chen, JRC van der Maarel, PS Doyle, J Yan
Biophysical journal 109 (11), 2338-2351, 2015
292015
Mechanosensing of DNA bending in a single specific protein-DNA complex
S Le, H Chen, P Cong, J Lin, P Droge, J Yan
Scientific Reports 3, 3508, 2013
292013
Effects of kink and flexible hinge defects on mechanical responses of short double-stranded DNA molecules
H Chen, J Yan
Physical Review E 77 (4), 041907, 2008
272008
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