Immune and genomic correlates of response to anti-PD-1 immunotherapy in glioblastoma J Zhao, AX Chen, RD Gartrell, AM Silverman, L Aparicio, T Chu, ... Nature medicine 25 (3), 462-469, 2019 | 670 | 2019 |
Spatiotemporal genomic architecture informs precision oncology in glioblastoma JK Lee, J Wang, JK Sa, E Ladewig, HO Lee, IH Lee, HJ Kang, ... Nature genetics 49 (4), 594-599, 2017 | 269 | 2017 |
Predicting clinical outcomes in glioblastoma: an application of topological and functional data analysis L Crawford, A Monod, AX Chen, S Mukherjee, R Rabadán Journal of the American Statistical Association 115 (531), 1139-1150, 2020 | 130* | 2020 |
Tissue-resident memory T cells mediate immune homeostasis in the human pancreas through the PD-1/PD-L1 pathway SP Weisberg, DJ Carpenter, M Chait, P Dogra, RD Gartrell-Corrado, ... Cell reports 29 (12), 3916-3932. e5, 2019 | 91 | 2019 |
Midkine rewires the melanoma microenvironment toward a tolerogenic and immune-resistant state D Cerezo-Wallis, M Contreras-Alcalde, K Troulé, X Catena, C Mucientes, ... Nature medicine 26 (12), 1865-1877, 2020 | 74 | 2020 |
Single-cell characterization of macrophages in glioblastoma reveals MARCO as a mesenchymal pro-tumor marker AX Chen, RD Gartrell, J Zhao, PS Upadhyayula, W Zhao, J Yuan, ... Genome medicine 13 (1), 88, 2021 | 64 | 2021 |
ERK1/2 phosphorylation predicts survival following anti-PD-1 immunotherapy in recurrent glioblastoma VA Arrieta, AX Chen, JR Kane, SJ Kang, C Kassab, C Dmello, J Zhao, ... Nature cancer 2 (12), 1372-1386, 2021 | 51 | 2021 |
Dynamics of a producer-freeloader ecosystem on the brink of collapse A Chen, A Sanchez, L Dai, J Gore Nature communications 5 (1), 3713, 2014 | 50 | 2014 |
A phase I study of the combination of pexidartinib and sirolimus to target tumor-associated macrophages in unresectable sarcoma and malignant peripheral nerve sheath tumors GA Manji, BA Van Tine, SM Lee, AG Raufi, I Pellicciotta, AC Hirbe, ... Clinical Cancer Research 27 (20), 5519-5527, 2021 | 41 | 2021 |
Author Correction: Immune and genomic correlates of response to anti-PD-1 immunotherapy in glioblastoma. J Zhao, AX Chen, RD Gartrell, AM Silverman, L Aparicio, T Chu, ... Nature medicine 25 (6), 1022-1022, 2019 | 23 | 2019 |
Linking transcriptomic and imaging data defines features of a favorable tumor immune microenvironment and identifies a combination biomarker for primary melanoma RD Gartrell-Corrado, AX Chen, EM Rizk, DK Marks, MH Bogardus, ... Cancer research 80 (5), 1078-1087, 2020 | 20 | 2020 |
Neoadjuvant chemoradiation alters the immune microenvironment in pancreatic ductal adenocarcinoma RD Gartrell, T Enzler, PS Kim, BT Fullerton, L Fazlollahi, AX Chen, ... Oncoimmunology 11 (1), 2066767, 2022 | 9 | 2022 |
A fast semi-automatic segmentation tool for processing brain tumor images AX Chen, R Rabadán Towards Integrative Machine Learning and Knowledge Extraction: BIRS Workshop …, 2017 | 5 | 2017 |
Scale-free structure of cancer networks and their vulnerability to hub-directed combination therapy AX Chen, CJ Zopf, J Mettetal, WC Shyu, J Bolen, A Chakravarty, S Palani bioRxiv, 2020.07. 01.159657, 2020 | 2 | 2020 |
Using game theory to investigate the therapeutic potential of disrupting tumor-microenvironment interactions D Van Egeren, A Chen, M Stoddard, L Yuan, A Chakravarty Cancer Research 84 (6_Supplement), 7378-7378, 2024 | | 2024 |
Model-derived progression-free survival (mPFS): A better metric for patient-derived xenograft studies A Chen, M Stoddard, L Yuan, D Van Egeren, A Chakravarty, D Bottino Cancer Research 84 (6_Supplement), 6904-6904, 2024 | | 2024 |
Understanding three-drug combinations: optimizing scheduling while avoiding toxicity M Stoddard, L Yuan, D Van Egeren, A Chen, D Bottino, A Chakravarty Cancer Research 84 (6_Supplement), 4761-4761, 2024 | | 2024 |
Impact of drug combination schedules on the evolution of tumor resistance M Stoddard, A Chen, L Yuan, D Van Egeren, D Bottino, A Chakravarty Cancer Research 84 (6_Supplement), 4310-4310, 2024 | | 2024 |
Blood brain barrier masks effects of dosing strategy M Stoddard, A Chen, L Yuan, D Van Egeren, A Chakravarty Cancer Research 84 (6_Supplement), 7182-7182, 2024 | | 2024 |
Cytotoxic chemotherapy potentiates the immune response and efficacy of combination CXCR4/PD-1 inhibition in models of pancreatic ductal adenocarcinoma AG Raufi, I Pellicciotta, C Palermo, S Sastra, A Chen, E Alouani, C Maurer, ... bioRxiv, 2023.12. 24.573257, 2023 | | 2023 |