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Lu Chen (陈路)
Lu Chen (陈路)
Verified email at scu.edu.cn
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Cited by
Year
An atlas of genetic influences on human blood metabolites
SY Shin, EB Fauman, AK Petersen, J Krumsiek, R Santos, J Huang, ...
Nature genetics 46 (6), 543-550, 2014
12552014
The allelic landscape of human blood cell trait variation and links to common complex disease
WJ Astle, H Elding, T Jiang, D Allen, D Ruklisa, AL Mann, D Mead, ...
Cell 167 (5), 1415-1429. e19, 2016
11692016
The UK10K project identifies rare variants in health and disease
UK10K consortium
Nature 526 (7571), 82, 2015
1081*2015
A vaccine targeting the RBD of the S protein of SARS-CoV-2 induces protective immunity
J Yang, W Wang, Z Chen, S Lu, F Yang, Z Bi, L Bao, F Mo, X Li, Y Huang, ...
Nature 586 (7830), 572-577, 2020
7142020
Genetic drivers of epigenetic and transcriptional variation in human immune cells
L Chen, B Ge, FP Casale, L Vasquez, T Kwan, D Garrido-Martín, S Watt, ...
Cell 167 (5), 1398-1414. e24, 2016
6482016
Transcriptional diversity during lineage commitment of human blood progenitors
L Chen, M Kostadima, JHA Martens, G Canu, SP Garcia, E Turro, ...
Science 345 (6204), 1251033, 2014
3282014
Alternative splicing and the evolution of phenotypic novelty
SJ Bush, L Chen, JM Tovar-Corona, AO Urrutia
Philosophical Transactions of the Royal Society B: Biological Sciences 372 …, 2017
1772017
Correcting for Differential Transcript Coverage Reveals a Strong Relationship between Alternative Splicing and Organism Complexity
L Chen, SJ Bush, JM Tovar-Corona, A Castillo-Morales, AO Urrutia
Molecular biology and evolution 31 (6), 1402-1413, 2014
1552014
Genome-wide analysis of differential transcriptional and epigenetic variability across human immune cell types
S Ecker, L Chen, V Pancaldi, FO Bagger, JM Fernández, ...
Genome biology 18 (1), 1-17, 2017
1152017
Genomic monitoring of SARS-CoV-2 uncovers an Nsp1 deletion variant that modulates type I interferon response
J Lin, C Tang, H Wei, B Du, C Chen, M Wang, Y Zhou, M Yu, L Cheng, ...
Cell host & microbe 29 (3), 489-502. e8, 2021
1082021
Functional variation in allelic methylomes underscores a strong genetic contribution and reveals novel epigenetic alterations in the human epigenome
WA Cheung, X Shao, A Morin, V Siroux, T Kwan, B Ge, D Aïssi, L Chen, ...
Genome biology 18 (1), 1-21, 2017
902017
Alternative splicing: a potential source of functional innovation in the eukaryotic genome
L Chen, JM Tovar-Corona, AO Urrutia
International journal of evolutionary biology 2012, 2012
902012
Discovery and refinement of genetic loci associated with cardiometabolic risk using dense imputation maps
V Iotchkova, J Huang, JA Morris, D Jain, C Barbieri, K Walter, JL Min, ...
Nature genetics 48 (11), 1303-1312, 2016
802016
A rare variant in APOC3 is associated with plasma triglyceride and VLDL levels in Europeans
NJ Timpson, K Walter, JL Min, I Tachmazidou, G Malerba, SY Shin, ...
Nature communications 5 (1), 1-11, 2014
802014
Characteristics of genomic alterations of lung adenocarcinoma in young never‐smokers
W Luo, P Tian, Y Wang, H Xu, L Chen, C Tang, Y Shu, S Zhang, Z Wang, ...
International journal of cancer 143 (7), 1696-1705, 2018
642018
Whole-Exome Sequencing Identifies Loci Associated with Blood Cell Traits and Reveals a Role for Alternative GFI1B Splice Variants in Human Hematopoiesis
LM Polfus, RK Khajuria, UM Schick, N Pankratz, R Pazoki, JA Brody, ...
The American Journal of Human Genetics 99 (2), 481-488, 2016
632016
Sequential fate-switches in stem-like cells drive the tumorigenic trajectory from human neural stem cells to malignant glioma
X Wang, R Zhou, Y Xiong, L Zhou, X Yan, M Wang, F Li, C Xie, Y Zhang, ...
Cell research 31 (6), 684-702, 2021
522021
KMT2C deficiency promotes small cell lung cancer metastasis through DNMT3A-mediated epigenetic reprogramming
F Na, X Pan, J Chen, X Chen, M Wang, P Chi, L You, L Zhang, A Zhong, ...
Nature Cancer, 1-15, 2022
462022
Presence–Absence Variation in A. thaliana Is Primarily Associated with Genomic Signatures Consistent with Relaxed Selective Constraints
SJ Bush, A Castillo-Morales, JM Tovar-Corona, L Chen, PX Kover, ...
Molecular biology and evolution 31 (1), 59-69, 2014
452014
Increased levels of noisy splicing in cancers, but not for oncogene-derived transcripts
L Chen, JM Tovar-Corona, AO Urrutia
Human molecular genetics 20 (22), 4422-4429, 2011
432011
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Articles 1–20