Severe malarial anemia: innate immunity and pathogenesis DJ Perkins, T Were, GC Davenport, P Kempaiah, JB Hittner, JM Ong'echa International journal of biological sciences 7 (9), 1427, 2011 | 411 | 2011 |
Natural infection of Plasmodium brasilianum in humans: man and monkey share quartan malaria parasites in the Venezuelan Amazon A Lalremruata, M Magris, S Vivas-Martínez, M Koehler, M Esen, ... EBioMedicine 2 (9), 1186-1192, 2015 | 165 | 2015 |
Discovery of New Hydroxyethylamine Analogs against 3CLpro Protein Target of SARS-CoV-2: Molecular Docking, Molecular Dynamics Simulation, and Structure–Activity Relationship … S Kumar, PP Sharma, U Shankar, D Kumar, SK Joshi, L Pena, ... J. Chem. Inf. Model, 2020 | 119 | 2020 |
Mycobacterium abscessus glycopeptidolipid prevents respiratory epithelial TLR2 signaling as measured by HβD2 gene expression and IL-8 release LB Davidson, R Nessar, P Kempaiah, DJ Perkins, TF Byrd PloS one 6 (12), e29148, 2011 | 71 | 2011 |
Mechanisms of erythropoiesis inhibition by malarial pigment and malaria‐induced proinflammatory mediators in an in vitro model GA Awandare, P Kempaiah, DO Ochiel, P Piazza, CC Keller, DJ Perkins American journal of hematology 86 (2), 155-162, 2011 | 67 | 2011 |
A review of the preclinical and clinical efficacy of remdesivir, hydroxychloroquine, and lopinavir-ritonavir treatments against COVID-19 D Maciorowski, SZE Idrissi, Y Gupta, BJ Medernach, MB Burns, ... SLAS DISCOVERY: Advancing the Science of Drug Discovery 25 (10), 1108-1122, 2020 | 40 | 2020 |
Human tissue factor pathway inhibitor-2 induces caspase-mediated apoptosis in a human fibrosarcoma cell line P Kempaiah, W Kisiel Apoptosis 13, 702-715, 2008 | 39 | 2008 |
Identification of a human TFPI-2 splice variant that is upregulated in human tumor tissues P Kempaiah, HS Chand, W Kisiel Molecular cancer 6, 1-11, 2007 | 36 | 2007 |
Functional haplotypes of Fc gamma (Fcγ) receptor (FcγRIIA and FcγRIIIB) predict risk to repeated episodes of severe malarial anemia and mortality in Kenyan children C Ouma, GC Davenport, S Garcia, P Kempaiah, A Chaudhary, T Were, ... Human genetics 131, 289-299, 2012 | 35 | 2012 |
Bisindolylmaleimide IX: A novel anti-SARS-CoV2 agent targeting viral main protease 3CLpro demonstrated by virtual screening pipeline and in-vitro validation assays Y Gupta, D Maciorowski, SE Zak, KA Jones, RS Kathayat, SA Azizi, ... Methods 195, 57-71, 2021 | 34 | 2021 |
Fluorinated scaffolds for antimalarial drug discovery C Upadhyay, M Chaudhary, RN De Oliveira, A Borbas, P Kempaiah, ... Expert Opinion on Drug Discovery 15 (6), 705-718, 2020 | 33 | 2020 |
Heparin: A simplistic repurposing to prevent SARS-CoV-2 transmission in light of its in-vitro nanomolar efficacy Y Gupta, D Maciorowski, SE Zak, CV Kulkarni, AS Herbert, R Durvasula, ... International Journal of Biological Macromolecules 183, 203-212, 2021 | 30 | 2021 |
Antiplasmodial activity of hydroxyethylamine analogs: synthesis, biological activity and structure activity relationship of plasmepsin inhibitors AK Singh, V Rajendran, S Singh, P Kumar, Y Kumar, A Singh, W Miller, ... Bioorganic & medicinal chemistry 26 (13), 3837-3844, 2018 | 28 | 2018 |
Iron dysregulation in COVID‐19 and reciprocal evolution of SARS‐CoV‐2: Natura nihil frustra facit Y Gupta, D Maciorowski, B Medernach, DP Becker, R Durvasula, ... Journal of Cellular Biochemistry, 2022 | 26 | 2022 |
Protein structure-based in-silico approaches to drug discovery: Guide to COVID-19 therapeutics Y Gupta, OV Savytskyi, M Coban, A Venugopal, V Pleqi, CA Weber, ... Molecular Aspects of Medicine 91, 101151, 2023 | 24 | 2023 |
A novel compound active against SARS-CoV-2 targeting uridylate-specific endoribonuclease (NendoU/NSP15): in silico and in vitro investigations S Kumar, Y Gupta, SE Zak, C Upadhyay, N Sharma, AS Herbert, ... RSC Medicinal Chemistry 12 (10), 1757-1764, 2021 | 24 | 2021 |
Functional promoter haplotypes of interleukin-18 condition susceptibility to severe malarial anemia and childhood mortality SB Anyona, P Kempaiah, E Raballah, C Ouma, T Were, GC Davenport, ... Infection and immunity 79 (12), 4923-4932, 2011 | 23 | 2011 |
Reduced parasite burden in children with falciparum malaria and bacteremia coinfections: role of mediators of inflammation GC Davenport, JB Hittner, V Otieno, Z Karim, H Mukundan, PW Fenimore, ... Mediators of inflammation 2016, 2016 | 22 | 2016 |
Fast-acting small molecules targeting malarial aspartyl proteases, plasmepsins, inhibit malaria infection at multiple life stages S Singh, V Rajendran, J He, AK Singh, AO Achieng, Vandana, A Pant, ... ACS Infectious Diseases 5 (2), 184-198, 2018 | 21 | 2018 |
Reduced Hsp70 and glutamine in pediatric severe malaria anemia: role of hemozoin in suppressing Hsp70 and NF-κB activation P Kempaiah, K Dokladny, Z Karim, E Raballah, JM Ong’echa, PL Moseley, ... Molecular Medicine 22, 570-584, 2016 | 21 | 2016 |