Functional aging in the nervous system contributes to age-dependent motor activity decline in C. elegans J Liu, B Zhang, H Lei, Z Feng, J Liu, AL Hsu, XZS Xu Cell metabolism 18 (3), 392-402, 2013 | 146 | 2013 |
The neuronal kinesin UNC-104/KIF1A is a key regulator of synaptic aging and insulin signaling-regulated memory LB Li, H Lei, RN Arey, P Li, J Liu, CT Murphy, XZS Xu, K Shen Current Biology 26 (5), 605-615, 2016 | 68 | 2016 |
Promotion of behavior and neuronal function by reactive oxygen species in C. elegans G Li, J Gong, H Lei, J Liu, XZS Xu Nature communications 7 (1), 13234, 2016 | 57 | 2016 |
Tumor copy number deconvolution integrating bulk and single-cell sequencing data H Lei, B Lyu, EM Gertz, AA Schäffer, X Shi, K Wu, G Li, L Xu, Y Hou, ... Journal of Computational Biology 27 (4), 565-598, 2020 | 18 | 2020 |
Tumor heterogeneity assessed by sequencing and fluorescence in situ hybridization (FISH) data H Lei, EM Gertz, AA Schäffer, X Fu, Y Tao, K Heselmeyer-Haddad, ... Bioinformatics 37 (24), 4704-4711, 2021 | 10 | 2021 |
Robust and accurate deconvolution of tumor populations uncovers evolutionary mechanisms of breast cancer metastasis Y Tao, H Lei, X Fu, AV Lee, J Ma, R Schwartz Bioinformatics 36 (Supplement_1), i407-i416, 2020 | 8 | 2020 |
Reconstructing tumor clonal lineage trees incorporating single-nucleotide variants, copy number alterations and structural variations X Fu, H Lei, Y Tao, R Schwartz Bioinformatics 38 (Supplement_1), i125-i133, 2022 | 7 | 2022 |
Phylogenies derived from matched transcriptome reveal the evolution of cell populations and temporal order of perturbed pathways in breast cancer brain metastases Y Tao, H Lei, AV Lee, J Ma, R Schwartz Mathematical and Computational Oncology: First International Symposium …, 2019 | 5 | 2019 |
A clonal evolution simulator for planning somatic evolution studies A Srivatsa, H Lei, R Schwartz Journal of Computational Biology 30 (8), 831-847, 2023 | 4 | 2023 |
Neural network deconvolution method for resolving pathway-level progression of tumor clonal expression programs with application to breast cancer brain metastases Y Tao, H Lei, AV Lee, J Ma, R Schwartz Frontiers in physiology 11, 1055, 2020 | 4 | 2020 |
Joint clustering of single-cell sequencing and fluorescence in situ hybridization data for reconstructing clonal heterogeneity in cancers X Fu, H Lei, Y Tao, K Heselmeyer-Haddad, I Torres, M Dean, T Ried, ... Journal of Computational Biology 28 (11), 1035-1051, 2021 | 3 | 2021 |
Semi-deconvolution of bulk and single-cell RNA-seq data with application to metastatic progression in breast cancer H Lei, XA Guo, Y Tao, K Ding, X Fu, S Oesterreich, AV Lee, R Schwartz Bioinformatics 38 (Supplement_1), i386-i394, 2022 | 2 | 2022 |
A simulator for somatic evolution study design A Srivatsa, H Lei, R Schwartz bioRxiv, 2022.05. 01.487551, 2022 | 1 | 2022 |
Improved deconvolution of combined bulk and single-cell RNA-sequencing data H Lei, XA Guo, Y Tao, K Ding, X Fu, S Oesterreich, AV Lee, R Schwartz Cancer Research 82 (12_Supplement), 5031-5031, 2022 | | 2022 |
Deconvolution of copy number alterations combining bulk and single-cell genomic data H Lei, B Lyu, EM Gertz, AA Schaeffer, X Shi, K Wu, G Li, L Xu, Y Hou, ... Cancer Research 79 (13_Supplement), 1650-1650, 2019 | | 2019 |
Tumor Copy Number Data Deconvolution Integrating Bulk and Single-cell Sequencing Data H Lei, B Lyu, EM Gertz, AA Schaffer, R Schwartz 2018 IEEE 8th International Conference on Computational Advances in Bio and …, 2018 | | 2018 |