Követés
Kazuo Takayama
Kazuo Takayama
E-mail megerősítve itt: cira.kyoto-u.ac.jp
Cím
Hivatkozott rá
Hivatkozott rá
Év
3D spheroid culture of hESC/hiPSC-derived hepatocyte-like cells for drug toxicity testing
K Takayama, K Kawabata, Y Nagamoto, K Kishimoto, K Tashiro, ...
Biomaterials 34 (7), 1781-1789, 2013
2842013
Efficient generation of functional hepatocytes from human embryonic stem cells and induced pluripotent stem cells by HNF4α transduction
K Takayama, M Inamura, K Kawabata, K Katayama, M Higuchi, K Tashiro, ...
Molecular Therapy 20 (1), 127-137, 2012
2632012
Prediction of interindividual differences in hepatic functions and drug sensitivity by using human iPS-derived hepatocytes
K Takayama, Y Morisaki, S Kuno, Y Nagamoto, K Harada, N Furukawa, ...
Proceedings of the National Academy of Sciences 111 (47), 16772-16777, 2014
1822014
Generation of metabolically functioning hepatocytes from human pluripotent stem cells by FOXA2 and HNF1α transduction
K Takayama, M Inamura, K Kawabata, M Sugawara, K Kikuchi, M Higuchi, ...
Journal of hepatology 57 (3), 628-636, 2012
1822012
In vitro and animal models for SARS-CoV-2 research
K Takayama
Trends in pharmacological sciences 41 (8), 513-517, 2020
1792020
Efficient generation of hepatoblasts from human ES cells and iPS cells by transient overexpression of homeobox gene HEX
M Inamura, K Kawabata, K Takayama, K Tashiro, F Sakurai, K Katayama, ...
Molecular Therapy 19 (2), 400-407, 2011
1292011
The promotion of hepatic maturation of human pluripotent stem cells in 3D co-culture using type I collagen and Swiss 3T3 cell sheets
Y Nagamoto, K Tashiro, K Takayama, K Ohashi, K Kawabata, F Sakurai, ...
Biomaterials 33 (18), 4526-4534, 2012
1252012
Transplantation of a human iPSC-derived hepatocyte sheet increases survival in mice with acute liver failure
Y Nagamoto, K Takayama, K Ohashi, R Okamoto, F Sakurai, M Tachibana, ...
Journal of hepatology 64 (5), 1068-1075, 2016
1232016
The structural basis of accelerated host cell entry by SARS‐CoV‐2
M Seyran, K Takayama, VN Uversky, K Lundstrom, G Palù, SP Sherchan, ...
The FEBS journal 288 (17), 5010-5020, 2021
1172021
Carbon-based nanomaterials: promising antiviral agents to combat COVID-19 in the microbial-resistant era
Á Serrano-Aroca, K Takayama, A Tuñón-Molina, M Seyran, SS Hassan, ...
ACS nano 15 (5), 8069-8086, 2021
892021
Highly efficient biallelic genome editing of human ES/iPS cells using a CRISPR/Cas9 or TALEN system
K Takayama, K Igai, Y Hagihara, R Hashimoto, M Hanawa, T Sakuma, ...
Nucleic acids research 45 (9), 5198-5207, 2017
812017
Long-term self-renewal of human ES/iPS-derived hepatoblast-like cells on human laminin 111-coated dishes
K Takayama, Y Nagamoto, N Mimura, K Tashiro, F Sakurai, M Tachibana, ...
Stem cell reports 1 (4), 322-335, 2013
792013
Efficient and directive generation of two distinct endoderm lineages from human ESCs and iPSCs by differentiation stage-specific SOX17 transduction
K Takayama, M Inamura, K Kawabata, K Tashiro, K Katayama, F Sakurai, ...
PloS one 6 (7), e21780, 2011
702011
Use of human hepatocyte-like cells derived from induced pluripotent stem cells as a model for hepatocytes in hepatitis C virus infection
T Yoshida, K Takayama, M Kondoh, F Sakurai, H Tani, N Sakamoto, ...
Biochemical and biophysical research communications 416 (1-2), 119-124, 2011
692011
Generation of human bronchial organoids for SARS-CoV-2 research
T Suzuki, Y Itoh, Y Sakai, A Saito, D Okuzaki, D Motooka, S Minami, ...
biorxiv, 2020
682020
Generation of safe and therapeutically effective human induced pluripotent stem cell‐derived hepatocyte‐like cells for regenerative medicine
K Takayama, N Akita, N Mimura, R Akahira, Y Taniguchi, M Ikeda, ...
Hepatology communications 1 (10), 1058-1069, 2017
612017
Generation of enterocyte-like cells from human induced pluripotent stem cells for drug absorption and metabolism studies in human small intestine
T Ozawa, K Takayama, R Okamoto, R Negoro, F Sakurai, M Tachibana, ...
Scientific reports 5 (1), 1-11, 2015
582015
CCAAT/enhancer binding protein-mediated regulation of TGFβ receptor 2 expression determines the hepatoblast fate decision
K Takayama, K Kawabata, Y Nagamoto, M Inamura, K Ohashi, H Okuno, ...
Development 141 (1), 91-100, 2014
542014
Direct conversion of human fibroblasts into hepatocyte-like cells by ATF5, PROX1, FOXA2, FOXA3, and HNF4A transduction
D Nakamori, H Akamine, K Takayama, F Sakurai, H Mizuguchi
Scientific reports 7 (1), 1-9, 2017
522017
Modeling of drug-mediated CYP3A4 induction by using human iPS cell-derived enterocyte-like cells
R Negoro, K Takayama, Y Nagamoto, F Sakurai, M Tachibana, ...
Biochemical and biophysical research communications 472 (4), 631-636, 2016
512016
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Cikkek 1–20