Design of protease activated optical contrast agents that exploit a latent lysosomotropic effect for use in fluorescence-guided surgery LO Ofori, NP Withana, TR Prestwood, M Verdoes, JJ Brady, MM Winslow, ... ACS chemical biology 10 (9), 1977-1988, 2015 | 113 | 2015 |
Non-invasive imaging of idiopathic pulmonary fibrosis using cathepsin protease probes NP Withana, X Ma, HM McGuire, M Verdoes, WA van der Linden, LO Ofori, ... Scientific reports 6 (1), 19755, 2016 | 99 | 2016 |
From dynamic combinatorial ‘hit’ to lead: in vitro and in vivo activity of compounds targeting the pathogenic RNAs that cause myotonic dystrophy LO Ofori, J Hoskins, M Nakamori, CA Thornton, BL Miller Nucleic acids research 40 (13), 6380-6390, 2012 | 81 | 2012 |
Design of a highly selective quenched activity-based probe and its application in dual color imaging studies of cathepsin S activity localization K Oresic Bender, L Ofori, WA van der Linden, ED Mock, GK Datta, ... Journal of the American Chemical Society 137 (14), 4771-4777, 2015 | 74 | 2015 |
Small-molecule inhibition of a depalmitoylase enhances Toxoplasma host-cell invasion MA Child, CI Hall, JR Beck, LO Ofori, VE Albrow, M Garland, PW Bowyer, ... Nature chemical biology 9 (10), 651-656, 2013 | 69 | 2013 |
Lomofungin and dilomofungin: inhibitors of MBNL1-CUG RNA binding with distinct cellular effects JW Hoskins, LO Ofori, CZ Chen, A Kumar, K Sobczak, M Nakamori, ... Nucleic acids research 42 (10), 6591-6602, 2014 | 62 | 2014 |
Labeling of active proteases in fresh-frozen tissues by topical application of quenched activity-based probes NP Withana, M Garland, M Verdoes, LO Ofori, E Segal, M Bogyo Nature protocols 11 (1), 184-191, 2016 | 57 | 2016 |
High-affinity recognition of HIV-1 frameshift-stimulating RNA alters frameshifting in vitro and interferes with HIV-1 infectivity LO Ofori, TA Hilimire, RP Bennett, NW Brown Jr, HC Smith, BL Miller Journal of Medicinal Chemistry 57 (3), 723-732, 2014 | 51 | 2014 |
Dual-modality activity-based probes as molecular imaging agents for vascular inflammation NP Withana, T Saito, X Ma, M Garland, C Liu, H Kosuge, M Amsallem, ... Journal of Nuclear Medicine 57 (10), 1583-1590, 2016 | 47 | 2016 |
Strategies for Recognition of Stem− Loop RNA Structures by Synthetic Ligands: Application to the HIV-1 Frameshift Stimulatory Sequence PB Palde, LO Ofori, PC Gareiss, J Lerea, BL Miller Journal of medicinal chemistry 53 (16), 6018-6027, 2010 | 40 | 2010 |
Nucleic acid binding compounds, methods of making, and use thereof BL Miller, LO Ofori, AV Gromova US Patent App. 13/976,852, 2014 | 3 | 2014 |
Solving the problem of sequence selective RNA recognition by small molecules with application to Myotonic Dystrophy and HIV LO Ofori University of Rochester, 2012 | 1 | 2012 |
Protease-activated contrast agents for in vivo imaging MS Bogyo, M Verdoes, L Ofori, NP Withana US Patent App. 18/489,653, 2024 | | 2024 |
Protease-activated contrast agents for in vivo imaging MS Bogyo, M Verdoes, L Ofori, NP Withana US Patent App. 18/053,682, 2024 | | 2024 |
Protease-activated contrast agents for in vivo imaging MS Bogyo, M Verdoes, L Ofori, NP Withana US Patent 11,828,752, 2023 | | 2023 |
CONTRAST AGENTS ACTIVATED BY A PROTEASE FOR IN VIVO IMAGING MS Bogyo, M VERDOES, L OFORI, NP WITHANA | | 2021 |
Protease-activated contrast agents for in vivo imaging MS Bogyo, M Verdoes, L Ofori, NP Withana US Patent App. 16/792,142, 2020 | | 2020 |
Protease-activated contrast agents for in vivo imaging MS Bogyo, M Verdoes, L Ofori, NP Withana US Patent 10,570,173, 2020 | | 2020 |
Non-invasive Imaging of Idiopathic Pulmonary Fibrosis Using Cathepsin Protease Probes H Collard, P Wolters, NP Withana, X Ma, HM McGuire, M Verdoes, ... | | 2016 |
New chemical probe technologies for diagnostic and intra-operative imaging applications L Ofori, N Withana, M Verdoes, J Sorger, M Bogyo ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 250, 2015 | | 2015 |