Matt Hutchings

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Ryan F. SeipkeUniversity of LeedsVerified email at leeds.ac.uk
Nick Le BrunProfessor of Biological ChemistryVerified email at uea.ac.uk
Douglas W. YuProfessor, School of Biological Sciences, University of East AngliaVerified email at uea.ac.uk
Mark J. ButtnerHead, Dept. of Molecular Microbiology, John Innes CentreVerified email at jic.ac.uk
Murrell JCUniversity of East Anglia,Verified email at uea.ac.uk
John MunnochResearch associate, University of StrathclydeVerified email at strath.ac.uk
Sutcliffe ICVerified email at unn.ac.uk
Tracy PalmerProfessor of Microbiology, Newcastle UniversityVerified email at newcastle.ac.uk
Rebecca DevinePhD Student, University of East AngliaVerified email at uea.ac.uk
Paul A HoskissonProfessor of Molecular Microbiology, University of Strathclyde, Glasgow, UK Twitter @paulhoskissonVerified email at strath.ac.uk
Hee-Jeon HongOxford Brookes UniversityVerified email at brookes.ac.uk
Andrew ThomsonSchool of Chemistry University of East Anglia, Norwich, UKVerified email at uea.ac.uk
Zhiwei Qin (秦志伟)Beijing Normal UniversityVerified email at bnu.edu.cn
Mervyn BibbProfessor of Molecular Microbiology, John Innes CentreVerified email at jic.ac.uk
Mahmoud Al-BassamVerified email at ucsd.edu
Gilles van WezelProfessor of Molecular Biotechnology, Leiden University; Microbial Ecology, NIOO-KNAWVerified email at biology.leidenuniv.nl
Stephen SpiroProfessor of Biological Sciences, University of Texas at DallasVerified email at utdallas.edu
Jacobus J. BoomsmaProfessor of Evolutionary Biology, University of CopenhagenVerified email at bio.ku.dk
Ray DixonProfessor of Molecular Microbiology. John Innes CentreVerified email at jic.ac.uk
Nicholas TuckerUniversity of SuffolkVerified email at uos.ac.uk

Matt Hutchings

Group Leader at the John Innes Centre. @MattHutchings10

Verified email at jic.ac.uk - Homepage

Actinomycetes Leafcutter ants Antibiotics Synthetic biology


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Antibiotics: past, present and future MI Hutchings, AW Truman, B Wilkinson Current opinion in microbiology 51, 72-80, 2019	1418	2019
Streptomyces as symbionts: an emerging and widespread theme? RF Seipke, M Kaltenpoth, MI Hutchings FEMS Microbiology Reviews, 2011	451	2011
Cell envelope stress response in Gram-positive bacteria S Jordan, MI Hutchings, T Mascher FEMS microbiology reviews 32 (1), 107-146, 2008	444	2008
Chemical ecology of antibiotic production by actinomycetes A Van der Meij, SF Worsley, MI Hutchings, GP van Wezel FEMS microbiology reviews 41 (3), 392-416, 2017	376	2017
A mixed community of actinomycetes produce multiple antibiotics for the fungus farming ant Acromyrmex octospinosus J Barke, RF Seipke, S Grüschow, D Heavens, N Drou, MJ Bibb, RJM Goss, ... BMC biology 8, 1-10, 2010	270	2010
Lipoprotein biogenesis in Gram-positive bacteria: knowing when to hold ‘em, knowing when to fold ‘em MI Hutchings, T Palmer, DJ Harrington, IC Sutcliffe Trends in microbiology 17 (1), 13-21, 2009	261	2009
A Single Streptomyces Symbiont Makes Multiple Antifungals to Support the Fungus Farming Ant Acromyrmex octospinosus RF Seipke, J Barke, C Brearley, L Hill, DW Yu, RJM Goss, MI Hutchings PLoS one 6 (8), e22028, 2011	189	2011
The role of the novel Fem protein VanK in vancomycin resistance in Streptomyces coelicolor HJ Hong, MI Hutchings, LM Hill, MJ Buttner Journal of Biological Chemistry 280 (13), 13055-13061, 2005	179	2005
Sensing and responding to diverse extracellular signals? Analysis of the sensor kinases and response regulators of Streptomyces coelicolor A3(2) MI Hutchings, PA Hoskisson, G Chandra, MJ Buttner Microbiology 150 (9), 2795-2806, 2004	175	2004
The transcriptional repressor protein NsrR senses nitric oxide directly via a [2Fe-2S] cluster NP Tucker, MG Hicks, TA Clarke, JC Crack, G Chandra, NE Le Brun, ... PloS one 3 (11), e3623, 2008	163	2008
Characterization of an inducible vancomycin resistance system in Streptomyces coelicolor reveals a novel gene (vanK) required for drug resistance HJ Hong, MI Hutchings, JM Neu, GD Wright, MSB Paget, MJ Buttner Molecular microbiology 52 (4), 1107-1121, 2004	158	2004
The vancomycin resistance VanRS two‐component signal transduction system of Streptomyces coelicolor MI Hutchings, HJ Hong, MJ Buttner Molecular microbiology 59 (3), 923-935, 2006	146	2006
The NorR Protein of Escherichia coli Activates Expression of the Flavorubredoxin Gene norV in Response to Reactive Nitrogen Species MI Hutchings, N Mandhana, S Spiro Journal of Bacteriology 184 (16), 4640-4643, 2002	145	2002
Formicamycins, antibacterial polyketides produced by Streptomyces formicae isolated from African Tetraponera plant-ants Z Qin, JT Munnoch, R Devine, NA Holmes, RF Seipke, KA Wilkinson, ... Chemical Science 8 (4), 3218-3227, 2017	140	2017
Expression of matrix metalloproteinase‐2 and‐14 persists during early resolution of experimental liver fibrosis and might contribute to fibrolysis X Zhou, CJ Hovell, S Pawley, MI Hutchings, MJP Arthur, JP Iredale, ... Liver International 24 (5), 492-501, 2004	133	2004
There's NO stopping NsrR, a global regulator of the bacterial NO stress response NP Tucker, NE Le Brun, R Dixon, MI Hutchings Trends in microbiology 18 (4), 149-156, 2010	129	2010
Vancomycin resistance VanS/VanR two-component systems HJ Hong, MI Hutchings, MJ Buttner Bacterial Signal Transduction: Networks and Drug Targets, 200-213, 2008	124	2008
Biocontrol of cereal crop diseases using streptomycetes JT Newitt, SMM Prudence, MI Hutchings, SF Worsley Pathogens 8 (2), 78, 2019	102	2019
NsrR from Streptomyces coelicolor is a nitric oxide-sensing [4Fe-4S] cluster protein with a specialized regulatory function JC Crack, J Munnoch, EL Dodd, F Knowles, MM Al Bassam, S Kamali, ... Journal of Biological Chemistry 290 (20), 12689-12704, 2015	91	2015
Use and discovery of chemical elicitors that stimulate biosynthetic gene clusters in Streptomyces bacteria JM Moore, E Bradshaw, RF Seipke, MI Hutchings, M McArthur Methods in enzymology 517, 367-385, 2012	82	2012

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