MSE with mass defect filtering for in vitro and in vivo metabolite identification KP Bateman, J Castro‐Perez, M Wrona, JP Shockcor, K Yu, R Oballa, ... Rapid Communications in Mass Spectrometry: An International Journal Devoted …, 2007 | 307 | 2007 |
‘All‐in‐one’analysis for metabolite identification using liquid chromatography/hybrid quadrupole time‐of‐flight mass spectrometry with collision energy switching M Wrona, T Mauriala, KP Bateman, RJ Mortishire‐Smith, D O'Connor Rapid Communications in Mass Spectrometry: An International Journal Devoted …, 2005 | 204 | 2005 |
Discovery of MK-1439, an orally bioavailable non-nucleoside reverse transcriptase inhibitor potent against a wide range of resistant mutant HIV viruses B Côté, JD Burch, E Asante-Appiah, C Bayly, L Bédard, M Blouin, ... Bioorganic & medicinal chemistry letters 24 (3), 917-922, 2014 | 98 | 2014 |
Solution NMR structure and X-ray absorption analysis of the C-terminal zinc-binding domain of the SecA ATPase BR Dempsey, M Wrona, JM Moulin, GB Gloor, F Jalilehvand, G Lajoie, ... Biochemistry 43 (29), 9361-9371, 2004 | 43 | 2004 |
Discovery of 4-{1-[({1-[4-(trifluoromethyl) benzyl]-1H-indol-7-yl} carbonyl) amino] cyclopropyl} benzoic acid (MF-766), a highly potent and selective EP4 antagonist for … J Colucci, M Boyd, C Berthelette, JF Chiasson, Z Wang, Y Ducharme, ... Bioorganic & Medicinal Chemistry Letters 20 (12), 3760-3763, 2010 | 39 | 2010 |
A novel series of potent and selective EP4 receptor ligands: Facile modulation of agonism and antagonism MJ Boyd, C Berthelette, JF Chiasson, P Clark, J Colucci, D Denis, Y Han, ... Bioorganic & medicinal chemistry letters 21 (1), 484-487, 2011 | 34 | 2011 |
The discovery of 4-{1-[({2, 5-dimethyl-4-[4-(trifluoromethyl) benzyl]-3-thienyl} carbonyl) amino] cyclopropyl} benzoic acid (MK-2894), a potent and selective prostaglandin E2 … M Blouin, Y Han, J Burch, J Farand, C Mellon, M Gaudreault, M Wrona, ... Journal of medicinal chemistry 53 (5), 2227-2238, 2010 | 33 | 2010 |
Chemical profiling of ginseng species and ginseng herbal products using UPLC/QTOF-MS J Yuk, DN Patel, G Isaac, K Smith, M Wrona, HJ Olivos, K Yu Journal of the Brazilian Chemical Society 27, 1476-1483, 2016 | 24 | 2016 |
Novel interconnections in lipid metabolism revealed by overexpression of sphingomyelin synthase-1 GM Deevska, PP Dotson, AA Karakashian, G Isaac, M Wrona, SB Kelly, ... Journal of Biological Chemistry 292 (12), 5110-5122, 2017 | 22 | 2017 |
Integration of microfluidic LC with HRMS for the analysis of analytes in biofluids: past, present and future PD Rainville, JI Langridge, MD Wrona, ID Wilson, RS Plumb Bioanalysis 7 (11), 1397-1411, 2015 | 19 | 2015 |
Structure–activity relationships and pharmacokinetic parameters of quinoline acylsulfonamides as potent and selective antagonists of the EP4 receptor JD Burch, M Belley, R Fortin, D Deschênes, M Girard, J Colucci, J Farand, ... Bioorganic & medicinal chemistry letters 18 (6), 2048-2054, 2008 | 19 | 2008 |
Metabolic profiling of hoodia, chamomile, Terminalia species and evaluation of commercial preparations using ultrahigh-performance liquid chromatography quadrupole-time-of … B Avula, YH Wang, G Isaac, J Yuk, M Wrona, K Yu, IA Khan Planta Medica 83 (16), 1297-1308, 2017 | 15 | 2017 |
Synthesis of histamine dihydrochloride WL Yeh, C Antczak, JD Mcgolrick, MJ Roth, M Wrona US Patent 6,620,942, 2003 | 14 | 2003 |
Microflow UPLC and high-resolution MS as a sensitive and robust platform for quantitation of intact peptide hormones Z Chen, YW Alelyunas, MD Wrona, JR Kehler, ME Szapacs, CA Evans Bioanalysis 11 (13), 1275-1289, 2019 | 13 | 2019 |
Development and application of sub‐2‐μm particle CO2‐based chromatography coupled to mass spectrometry for comprehensive analysis of lipids in cottonseed extracts C Salazar, MD Jones, D Sturtevant, PJ Horn, J Crossley, K Zaman, ... Rapid Communications in Mass Spectrometry 31 (7), 591-605, 2017 | 13 | 2017 |
Characterization of (16R) and (16S)-hydroxyroquefortine C; diastereomeric metabolites from Penicillium crustosum DAOM 215343 LA Trimble, MW Sumarah, BA Blackwell, MD Wrona, JD Miller Tetrahedron Letters 53 (8), 956-958, 2012 | 13 | 2012 |
Metabolite identification using an ion mobility enhanced data‐independent acquisition strategy and automated data processing T Radchenko, CJ Kochansky, M Cancilla, MD Wrona, RJ Mortishire‐Smith, ... Rapid Communications in Mass Spectrometry 34 (12), e8792, 2020 | 12 | 2020 |
Development of an UPLC/MS–MS method for quantification of intact IGF-I from human serum NN Tanna, ME Lame, M Wrona Bioanalysis 12 (1), 53-65, 2020 | 12 | 2020 |
Naphthalene/quinoline amides and sulfonylureas as potent and selective antagonists of the EP4 receptor JD Burch, J Farand, J Colucci, C Sturino, Y Ducharme, RW Friesen, ... Bioorganic & medicinal chemistry letters 21 (3), 1041-1046, 2011 | 12 | 2011 |
An HS-MRM assay for the quantification of host-cell proteins in protein biopharmaceuticals by liquid chromatography ion mobility QTOF mass spectrometry C Doneanu, J Fang, Y Alelyunas, YQ Yu, M Wrona, W Chen JoVE (Journal of Visualized Experiments), e55325, 2018 | 10 | 2018 |