Mikael H Elias
Mikael H Elias
Associate Professor of Biochemistry, University of Minnesota
Verified email at umn.edu - Homepage
Cited by
Cited by
The molecular basis of phosphate discrimination in arsenate-rich environments
M Elias, A Wellner, K Goldin-Azulay, E Chabriere, JA Vorholt, TJ Erb, ...
Nature 491 (7422), 134-137, 2012
Structural basis for natural lactonase and promiscuous phosphotriesterase activities
M Elias, J Dupuy, L Merone, L Mandrich, E Porzio, S Moniot, D Rochu, ...
Journal of molecular biology 379 (5), 1017-1028, 2008
Catalytic versatility and backups in enzyme active sites: the case of serum paraoxonase 1
M Ben-David, M Elias, JJ Filippi, E Duñach, I Silman, JL Sussman, ...
Journal of molecular biology 418 (3-4), 181-196, 2012
What makes a protein fold amenable to functional innovation? Fold polarity and stability trade-offs
E Dellus-Gur, A Toth-Petroczy, M Elias, DS Tawfik
Journal of molecular biology 425 (14), 2609-2621, 2013
The universality of enzymatic rate–temperature dependency
M Elias, G Wieczorek, S Rosenne, DS Tawfik
Trends in Biochemical Sciences 39 (1), 1-7, 2014
Divergence and convergence in enzyme evolution: parallel evolution of paraoxonases from quorum-quenching lactonases
M Elias, DS Tawfik
Journal of Biological Chemistry 287 (1), 11-20, 2012
Characterisation of the organophosphate hydrolase catalytic activity of SsoPox
J Hiblot, G Gotthard, E Chabriere, M Elias
Scientific reports 2, 779, 2012
Interference in bacterial quorum sensing: a biopharmaceutical perspective
B Rémy, S Mion, L Plener, M Elias, E Chabrière, D Daudé
Frontiers in pharmacology 9, 203, 2018
Biotechnological applications of quorum quenching enzymes
J Bzdrenga, D Daudé, B Remy, P Jacquet, L Plener, M Elias, E Chabriere
Chemico-biological interactions 267, 104-115, 2017
Structural and enzymatic characterization of the lactonase sis lac from Sulfolobus islandicus
J Hiblot, G Gotthard, E Chabriere, M Elias
PloS one 7 (10), e47028, 2012
Inhaled lactonase reduces Pseudomonas aeruginosa quorum sensing and mortality in rat pneumonia
S Hraiech, J Hiblot, J Lafleur, H Lepidi, L Papazian, JM Rolain, D Raoult, ...
PLoS One 9 (10), e107125, 2014
Negative epistasis and evolvability in TEM-1 β-lactamase—the thin line between an enzyme's conformational freedom and disorder
E Dellus-Gur, M Elias, E Caselli, F Prati, MLM Salverda, JAGM De Visser, ...
Journal of molecular biology 427 (14), 2396-2409, 2015
Directed evolution of sulfotransferases and paraoxonases by ancestral libraries
U Alcolombri, M Elias, DS Tawfik
Journal of molecular biology 411 (4), 837-853, 2011
Effect of quorum quenching lactonase in clinical isolates of Pseudomonas aeruginosa and comparison with quorum sensing inhibitors
A Guendouze, L Plener, J Bzdrenga, P Jacquet, B Rémy, M Elias, ...
Frontiers in Microbiology 8, 227, 2017
Differential active site loop conformations mediate promiscuous activities in the lactonase Sso Pox
J Hiblot, G Gotthard, M Elias, E Chabriere
PloS one 8 (9), e75272, 2013
Structural determinants of the high thermal stability of SsoPox from the hyperthermophilic archaeon Sulfolobus solfataricus
P Del Vecchio, M Elias, L Merone, G Graziano, J Dupuy, L Mandrich, ...
Extremophiles 13 (3), 461-470, 2009
Catalytic metal ion rearrangements underline promiscuity and evolvability of a metalloenzyme
M Ben-David, G Wieczorek, M Elias, I Silman, JL Sussman, DS Tawfik
Journal of molecular biology 425 (6), 1028-1038, 2013
Elucidation of the phosphate binding mode of DING proteins revealed by subangstrom X-ray crystallography
D Liebschner, M Elias, S Moniot, B Fournier, K Scott, C Jelsch, B Guillot, ...
Journal of the American Chemical Society 131 (22), 7879-7886, 2009
Current and emerging strategies for organophosphate decontamination: special focus on hyperstable enzymes
P Jacquet, D Daudé, J Bzdrenga, P Masson, M Elias, E Chabrière
Environmental Science and Pollution Research 23 (9), 8200-8218, 2016
Tandem use of X‐ray crystallography and mass spectrometry to obtain ab initio the complete and exact amino acids sequence of HPBP, a human 38‐kDa apolipoprotein
H Diemer, M Elias, F Renault, D Rochu, C Contreras‐Martel, C Schaeffer, ...
Proteins: Structure, Function, and Bioinformatics 71 (4), 1708-1720, 2008
The system can't perform the operation now. Try again later.
Articles 1–20