Renal tubule albumin transport M Gekle Annu. Rev. Physiol. 67, 573-594, 2005 | 343 | 2005 |
The IL-1β, IL-6, and TNF cytokine triad is associated with post-acute sequelae of COVID-19 C Schultheiß, E Willscher, L Paschold, C Gottschick, B Klee, SS Henkes, ... Cell Reports Medicine 3 (6), 2022 | 265 | 2022 |
Cubilin-and megalin-mediated uptake of albumin in cultured proximal tubule cells of opossum kidney XY Zhai, R Nielsen, H Birn, K Drumm, S Mildenberger, R Freudinger, ... Kidney international 58 (4), 1523-1533, 2000 | 258 | 2000 |
Characterization of two MDCK-cell subtypes as a model system to study principal cell and intercalated cell properties M Gekle, S Wünsch, H Oberleithner, S Silbernagl Pflügers Archiv 428, 157-162, 1994 | 231 | 1994 |
Nephrotoxicity of platinum complexes is related to basolateral organic cation transport T Ludwig, C Riethmüller, M Gekle, G Schwerdt, H Oberleithner Kidney international 66 (1), 196-202, 2004 | 215 | 2004 |
Angiotensin Converting Enzyme Inhibition and Angiotensin II AT1-Receptor Blockade Reduce the Levels of Asymmetrical NG, NG-Dimethylarginine in Human … C Delles, MP Schneider, S John, M Gekle, RE Schmieder American journal of hypertension 15 (7), 590-593, 2002 | 202 | 2002 |
Human mineralocorticoid receptor expression renders cells responsive for nongenotropic aldosterone actions C Grossmann, A Benesic, AW Krug, R Freudinger, S Mildenberger, ... Molecular Endocrinology 19 (7), 1697-1710, 2005 | 201 | 2005 |
Impact of extracellular acidity on the activity of P-glycoprotein and the cytotoxicity of chemotherapeutic drugs O Thews, B Gassner, DK Kelleher, G Schwerd, M Gekle Neoplasia 8 (2), 143-152, 2006 | 176 | 2006 |
Rapid activation of Na+/H+ exchange by aldosterone in renal epithelial cells requires Ca2+ and stimulation of a plasma membrane proton conductance. M Gekle, N Golenhofen, H Oberleithner, S Silbernagl Proceedings of the National Academy of Sciences 93 (19), 10500-10504, 1996 | 173 | 1996 |
Megalin is essential for renal proximal tubule reabsorption of 111In-DTPA-octreotide M de Jong, R Barone, E Krenning, B Bernard, M Melis, T Visser, M Gekle, ... Journal of Nuclear Medicine 46 (10), 1696-1700, 2005 | 168 | 2005 |
Acidic environment leads to ROS-induced MAPK signaling in cancer cells A Riemann, B Schneider, A Ihling, M Nowak, C Sauvant, O Thews, ... PloS one 6 (7), e22445, 2011 | 156 | 2011 |
New aspects of rapid aldosterone signaling C Grossmann, M Gekle Molecular and cellular endocrinology 308 (1-2), 53-62, 2009 | 150 | 2009 |
Aldosterone stimulates epidermal growth factor receptor expression AW Krug, C Grossmann, C Schuster, R Freudinger, S Mildenberger, ... Journal of Biological Chemistry 278 (44), 43060-43066, 2003 | 148 | 2003 |
Transforming growth factor‐β1 reduces megalin‐ and cubilin‐mediated endocytosis of albumin in proximal‐tubule‐derived opossum kidney cells M Gekle, P Knaus, R Nielsen, S Mildenberger, R Freudinger, V Wohlfarth, ... The Journal of physiology 552 (2), 471-481, 2003 | 146 | 2003 |
Ochratoxin A induces JNK activation and apoptosis in MDCK-C7 cells at nanomolar concentrations M Gekle, G Schwerdt, R Freudinger, S Mildenberger, D Wilflingseder, ... Journal of Pharmacology and Experimental Therapeutics 293 (3), 837-844, 2000 | 143 | 2000 |
Acidosis induces multi‐drug resistance in rat prostate cancer cells (AT1) in vitro and in vivo by increasing the activity of the p‐glycoprotein via activation of p38 C Sauvant, M Nowak, C Wirth, B Schneider, A Riemann, M Gekle, ... International journal of cancer 123 (11), 2532-2542, 2008 | 134 | 2008 |
Differential Stimulation of the Na+/H+ Exchanger Determines Chloroquine Uptake in Plasmodium falciparum S Wünsch, CP Sanchez, M Gekle, L Große-Wortmann, J Wiesner, ... The Journal of cell biology 140 (2), 335-345, 1998 | 130 | 1998 |
Metabolism and cytotoxic effects of T-2 toxin and its metabolites on human cells in primary culture M Königs, D Mulac, G Schwerdt, M Gekle, HU Humpf Toxicology 258 (2-3), 106-115, 2009 | 125 | 2009 |
Elevated mineralocorticoid receptor activity in aged rat vascular smooth muscle cells promotes a proinflammatory phenotype via extracellular signal-regulated kinase 1/2 mitogen … AW Krug, L Allenhöfer, R Monticone, G Spinetti, M Gekle, M Wang, ... Hypertension 55 (6), 1476-1483, 2010 | 123 | 2010 |
Inhibition of Na+− H+ exchange impairs receptor-mediated albumin endocytosis in renal proximal tubule-derived epithelial cells from opossum M Gekle, K Drumm, S Mildenberger, R Freudinger, B Gaßner, ... The Journal of physiology 520 (Pt 3), 709, 1999 | 123 | 1999 |