Követés
Costas Lyssiotis
Costas Lyssiotis
Associate Professor of Physiology, University of Michigan
E-mail megerősítve itt: lyssiotis.com - Kezdőlap
Cím
Hivatkozott rá
Hivatkozott rá
Év
Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism
H Ying, AC Kimmelman, CA Lyssiotis, S Hua, GC Chu, ...
Cell 149 (3), 656-670, 2012
19962012
Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway
J Son, CA Lyssiotis, H Ying, X Wang, S Hua, M Ligorio, RM Perera, ...
Nature 496 (7443), 101-105, 2013
19182013
Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function
A Viale, P Pettazzoni, CA Lyssiotis, H Ying, N Sánchez, M Marchesini, ...
Nature 514 (7524), 628-632, 2014
11982014
Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis
JW Locasale, AR Grassian, T Melman, CA Lyssiotis, KR Mattaini, AJ Bass, ...
Nature genetics 43 (9), 869-874, 2011
11822011
A colorectal cancer classification system that associates cellular phenotype and responses to therapy
A Sadanandam, CA Lyssiotis, K Homicsko, EA Collisson, WJ Gibb, ...
Nature medicine 19 (5), 619-625, 2013
10932013
Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion
CM Sousa, DE Biancur, X Wang, CJ Halbrook, MH Sherman, LI Zhang, ...
Nature 536 (7617), 479-483, 2016
9962016
Cysteine depletion induces pancreatic tumor ferroptosis in mice
MA Badgley, DM Kremer, HC Maurer, KE DelGiorno, HJ Lee, V Purohit, ...
Science 368 (6486), 85-89, 2020
8612020
ERK1/2-dependent phosphorylation and nuclear translocation of PKM2 promotes the Warburg effect
W Yang, Y Zheng, Y Xia, H Ji, X Chen, F Guo, CA Lyssiotis, K Aldape, ...
Nature cell biology 14 (12), 1295-1304, 2012
8272012
Metabolic interactions in the tumor microenvironment
CA Lyssiotis, AC Kimmelman
Trends in cell biology 27 (11), 863-875, 2017
7142017
Influence of threonine metabolism on S-adenosylmethionine and histone methylation
N Shyh-Chang, JW Locasale, CA Lyssiotis, Y Zheng, RY Teo, ...
Science 339 (6116), 222-226, 2013
6632013
Oxidative stress controls regulatory T cell apoptosis and suppressor activity and PD-L1-blockade resistance in tumor
T Maj, W Wang, J Crespo, H Zhang, W Wang, S Wei, L Zhao, L Vatan, ...
Nature immunology 18 (12), 1332-1341, 2017
5912017
Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer
KL Bryant, CA Stalnecker, D Zeitouni, JE Klomp, S Peng, AP Tikunov, ...
Nature medicine 25 (4), 628-640, 2019
5812019
A regenerative approach to the treatment of multiple sclerosis
VA Deshmukh, V Tardif, CA Lyssiotis, CC Green, B Kerman, HJ Kim, ...
Nature 502 (7471), 327-332, 2013
5282013
Reprogramming of murine fibroblasts to induced pluripotent stem cells with chemical complementation of Klf4
CA Lyssiotis, RK Foreman, J Staerk, M Garcia, D Mathur, S Markoulaki, ...
Proceedings of the National Academy of Sciences 106 (22), 8912-8917, 2009
4982009
MUC1 and HIF-1alpha signaling crosstalk induces anabolic glucose metabolism to impart gemcitabine resistance to pancreatic cancer
SK Shukla, V Purohit, K Mehla, V Gunda, NV Chaika, E Vernucci, RJ King, ...
Cancer cell 32 (1), 71-87. e7, 2017
4752017
Combining a PI3K inhibitor with a PARP inhibitor provides an effective therapy for BRCA1-related breast cancer
A Juvekar, LN Burga, H Hu, EP Lunsford, YH Ibrahim, J Balmañà, ...
Cancer discovery 2 (11), 1048-1063, 2012
4602012
Phosphoinositide 3-kinase regulates glycolysis through mobilization of aldolase from the actin cytoskeleton
H Hu, A Juvekar, CA Lyssiotis, EC Lien, JG Albeck, D Oh, G Varma, ...
Cell 164 (3), 433-446, 2016
3602016
Employing metabolism to improve the diagnosis and treatment of pancreatic cancer
CJ Halbrook, CA Lyssiotis
Cancer cell 31 (1), 5-19, 2017
3582017
Cancer SLC43A2 alters T cell methionine metabolism and histone methylation
Y Bian, W Li, DM Kremer, P Sajjakulnukit, S Li, J Crespo, ZC Nwosu, ...
Nature 585 (7824), 277-282, 2020
3502020
Macrophage-released pyrimidines inhibit gemcitabine therapy in pancreatic cancer
CJ Halbrook, C Pontious, I Kovalenko, L Lapienyte, S Dreyer, HJ Lee, ...
Cell metabolism 29 (6), 1390-1399. e6, 2019
3472019
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