Követés
Murillo Silva
Murillo Silva
Postdoctoral associate (MIT)
E-mail megerősítve itt: mit.edu
Cím
Hivatkozott rá
Hivatkozott rá
Év
Enhanced CAR–T cell activity against solid tumors by vaccine boosting through the chimeric receptor
L Ma, T Dichwalkar, JYH Chang, B Cossette, D Garafola, AQ Zhang, ...
Science 365 (6449), 162-168, 2019
3232019
Controlling timing and location in vaccines
DJ Irvine, A Aung, M Silva
Advanced Drug Delivery Reviews 158, 91-115, 2020
1702020
Multifaceted effects of antigen valency on B cell response composition and differentiation in vivo
Y Kato, RK Abbott, BL Freeman, S Haupt, B Groschel, M Silva, S Menis, ...
Immunity 53 (3), 548-563. e8, 2020
1592020
Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques
A Escolano, HB Gristick, ME Abernathy, J Merkenschlager, R Gautam, ...
Nature 570 (7762), 468-473, 2019
1432019
Germinal center hypoxia potentiates immunoglobulin class switch recombination
RK Abbott, M Thayer, J Labuda, M Silva, P Philbrook, DW Cain, H Kojima, ...
The Journal of Immunology 197 (10), 4014-4020, 2016
1132016
Hypoxia and hypoxia-inducible factor (HIF) downregulate antigen-presenting MHC class I molecules limiting tumor cell recognition by T cells
S Sethumadhavan, M Silva, P Philbrook, T Nguyen, SM Hatfield, A Ohta, ...
PloS one 12 (11), e0187314, 2017
1042017
Long-primed germinal centres with enduring affinity maturation and clonal migration
JH Lee, HJ Sutton, CA Cottrell, I Phung, G Ozorowski, LM Sewall, ...
Nature 609 (7929), 998-1004, 2022
852022
Enhancing humoral responses against HIV envelope trimers via nanoparticle delivery with stabilized synthetic liposomes
T Tokatlian, DW Kulp, AA Mutafyan, CA Jones, S Menis, E Georgeson, ...
Scientific Reports 8 (1), 16527, 2018
792018
A particulate saponin/TLR agonist vaccine adjuvant alters lymph flow and modulates adaptive immunity
M Silva, Y Kato, MB Melo, I Phung, BL Freeman, Z Li, K Roh, ...
Science immunology 6 (66), eabf1152, 2021
712021
Immunogenicity of RNA replicons encoding HIV Env immunogens designed for self-assembly into nanoparticles
M Melo, E Porter, Y Zhang, M Silva, N Li, B Dobosh, A Liguori, P Skog, ...
Molecular Therapy 27 (12), 2080-2090, 2019
702019
Engineered SARS-CoV-2 receptor binding domain improves manufacturability in yeast and immunogenicity in mice
NC Dalvie, SA Rodriguez-Aponte, BL Hartwell, LH Tostanoski, ...
Proceedings of the National Academy of Sciences 118 (38), e2106845118, 2021
682021
Intranasal vaccination with lipid-conjugated immunogens promotes antigen transmucosal uptake to drive mucosal and systemic immunity
BL Hartwell, MB Melo, P Xiao, AA Lemnios, N Li, JYH Chang, J Yu, ...
Science translational medicine 14 (654), eabn1413, 2022
442022
Can feeding the broiler breeder improve chick quality and offspring performance?
A Chang, J Halley, M Silva
Animal production science 56 (8), 1254-1262, 2016
432016
Disassembly of HIV envelope glycoprotein trimer immunogens is driven by antibodies elicited via immunization
HL Turner, R Andrabi, CA Cottrell, ST Richey, G Song, S Callaghan, ...
Science advances 7 (31), eabh2791, 2021
382021
Low protease activity in B cell follicles promotes retention of intact antigens after immunization
A Aung, A Cui, L Maiorino, AP Amini, JR Gregory, M Bukenya, Y Zhang, ...
Science 379 (6630), eabn8934, 2023
362023
The GS protein-coupled A2a adenosine receptor controls T cell help in the germinal center
RK Abbott, M Silva, J Labuda, M Thayer, DW Cain, P Philbrook, ...
Journal of Biological Chemistry 292 (4), 1211-1217, 2017
262017
Targeted elimination of immunodominant B cells drives the germinal center reaction toward subdominant epitopes
M Silva, TH Nguyen, P Philbrook, M Chu, O Sears, S Hatfield, RK Abbott, ...
Cell reports 21 (13), 3672-3680, 2017
252017
Broadly neutralizing antibodies to SARS-related viruses can be readily induced in rhesus macaques
W He, M Yuan, S Callaghan, R Musharrafieh, G Song, M Silva, N Beutler, ...
Science translational medicine 14 (657), eabl9605, 2022
242022
Sequential immunization of macaques elicits heterologous neutralizing antibodies targeting the V3-glycan patch of HIV-1 Env
A Escolano, HB Gristick, R Gautam, AT DeLaitsch, ME Abernathy, Z Yang, ...
Science translational medicine 13 (621), eabk1533, 2021
242021
Phosphate-mediated coanchoring of RBD immunogens and molecular adjuvants to alum potentiates humoral immunity against SARS-CoV-2
KA Rodrigues, SA Rodriguez-Aponte, NC Dalvie, JH Lee, W Abraham, ...
Science Advances 7 (50), eabj6538, 2021
202021
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