| Benchmark and integration of resources for the estimation of human transcription factor activities L Garcia-Alonso, CH Holland, MM Ibrahim, D Turei, J Saez-Rodriguez Genome research 29 (8), 1363-1375, 2019 | 832 | 2019 |
| decoupleR: Ensemble of computational methods to infer biological activities from omics data P Badia-i-Mompel, J Vélez Santiago, J Braunger, C Geiss, D Dimitrov, ... Bioinformatics Advances 2 (1), vbac016, 2022 | 349 | 2022 |
| Robustness and applicability of transcription factor and pathway analysis tools on single-cell RNA-seq data CH Holland, J Tanevski, J Perales-Patón, J Gleixner, MP Kumar, E Mereu, ... Genome Biology 21 (1), 36, 2020 | 282 | 2020 |
| Imbalanced gut microbiota fuels hepatocellular carcinoma development by shaping the hepatic inflammatory microenvironment KM Schneider, A Mohs, W Gui, EJC Galvez, LS Candels, L Hoenicke, ... Nature Communications 13 (1), 3964, 2022 | 134 | 2022 |
| Transfer of regulatory knowledge from human to mouse for functional genomics analysis CH Holland, B Szalai, J Saez-Rodriguez Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1863 (6), 194431, 2020 | 134 | 2020 |
| Hepatocyte-specific NRF2 activation controls fibrogenesis and carcinogenesis in steatohepatitis A Mohs, T Otto, KM Schneider, M Peltzer, M Boekschoten, CH Holland, ... Journal of Hepatology 74 (3), 638-648, 2021 | 115 | 2021 |
| Influence of Liver Fibrosis on Lobular Zonation A Ghallab, M Myllys, C H Holland, A Zaza, W Murad, R Hassan, ... Cells 8 (12), 1556, 2019 | 65 | 2019 |
| Signatures of cell death and proliferation in perturbation transcriptomics data—from confounding factor to effective prediction B Szalai, V Subramanian, CH Holland, R Alföldi, LG Puskás, ... Nucleic acids research 47 (19), 10010-10026, 2019 | 60 | 2019 |
| Consensus Transcriptional Landscape of Human End‐Stage Heart Failure RO Ramirez Flores, JD Lanzer, CH Holland, F Leuschner, P Most, ... Journal of the American Heart Association 10 (7), e019667, 2021 | 54 | 2021 |
| Spatio-Temporal Multiscale Analysis of Western Diet-Fed Mice Reveals a Translationally Relevant Sequence of Events during NAFLD Progression A Ghallab, M Myllys, A Friebel, J Duda, K Edlund, E Halilbasic, M Vucur, ... Cells 10 (10), 2516, 2021 | 41 | 2021 |
| Transcriptomic Cross‐Species Analysis of Chronic Liver Disease Reveals Consistent Regulation Between Humans and Mice CH Holland, RO Ramirez Flores, M Myllys, R Hassan, K Edlund, ... Hepatology Communications 6 (1), 161-177, 2022 | 39 | 2022 |
| A functional landscape of CKD entities from public transcriptomic data F Tajti, C Kuppe, A Antoranz, MM Ibrahim, H Kim, F Ceccarelli, ... Kidney International Reports 5 (2), 211-224, 2020 | 22* | 2020 |
| Transcription Factor Activity Inference in Systemic Lupus Erythematosus R Lopez-Dominguez, D Toro-Dominguez, J Martorell-Marugan, ... Life 11 (4), 299, 2021 | 12 | 2021 |
| Stabilization but no functional influence of HIF-1α expression in the intestinal epithelium during Salmonella Typhimurium infection L Robrahn, A Dupont, S Jumpertz, K Zhang, CH Holland, J Guillaume, ... Infection and Immunity 90 (2), e00222-21, 2022 | 8 | 2022 |
| Tolerance of repeated toxic injuries of murine livers is associated with steatosis and inflammation S Hammad, C Ogris, A Othman, P Erdoesi, W Schmidt-Heck, I Biermayer, ... Cell Death & Disease 14 (7), 414, 2023 | 6 | 2023 |
| FUNKI: interactive functional footprint-based analysis of omics data R Hernansaiz-Ballesteros, CH Holland, A Dugourd, J Saez-Rodriguez Bioinformatics 38 (7), 2075-2076, 2022 | 4 | 2022 |
| Role of WISP1 in Stellate Cell Migration and Liver Fibrosis D González, G Campos, L Pütter, A Friebel, CH Holland, L Holländer, ... Cells 13 (19), 1629, 2024 | 1 | 2024 |
| Increased sinusoidal export of drug glucuronides is a compensative mechanism in liver cirrhosis of mice R Fendt, A Ghallab, M Myllys, U Hofmann, R Hassan, Z Hobloss, ... Frontiers in Pharmacology 14, 2023 | | 2023 |
| Novel short-termed mouse model of intrahepatic cholangiocarcinoma by orthotopic transplantation of Hep-55.1 C in mice with human homology TH Wirtz, EF Brandt, P Fischer, C Holland, A Röth, M Baues, JN May, ... Zeitschrift für Gastroenterologie 60 (01), e34-e34, 2022 | | 2022 |
| From gene expression to pathway and transcription factor activities to study chronic liver diseases CH Holland | | 2021 |
Julio Saez RodriguezHeidelberg UniversityVerified email at uni-heidelberg.de
