Thomas B K Watkins
Thomas B K Watkins
Postdoc at the Francis Crick Institute and UCL
Verified email at crick.ac.uk
Title
Cited by
Cited by
Year
Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade
N McGranahan, AJS Furness, R Rosenthal, S Ramskov, R Lyngaa, ...
Science 351 (6280), 1463-1469, 2016
16362016
Tracking the evolution of non–small-cell lung cancer
M Jamal-Hanjani, GA Wilson, N McGranahan, NJ Birkbak, TBK Watkins, ...
New England Journal of Medicine 376 (22), 2109-2121, 2017
10792017
Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution
C Abbosh, NJ Birkbak, GA Wilson, M Jamal-Hanjani, T Constantin, ...
Nature 545 (7655), 446-451, 2017
7062017
Allele-specific HLA loss and immune escape in lung cancer evolution
N McGranahan, R Rosenthal, CT Hiley, AJ Rowan, TBK Watkins, ...
Cell 171 (6), 1259-1271. e11, 2017
4092017
Chromosomal instability drives metastasis through a cytosolic DNA response
SF Bakhoum, B Ngo, AM Laughney, JA Cavallo, CJ Murphy, P Ly, P Shah, ...
Nature 553 (7689), 467-472, 2018
3702018
Relapsed neuroblastomas show frequent RAS-MAPK pathway mutations
TF Eleveld, DA Oldridge, V Bernard, J Koster, LC Daage, SJ Diskin, ...
Nature genetics 47 (8), 864-871, 2015
3122015
Tracking cancer evolution reveals constrained routes to metastases: TRACERx renal
S Turajlic, H Xu, K Litchfield, A Rowan, T Chambers, JI Lopez, D Nicol, ...
Cell 173 (3), 581-594. e12, 2018
2642018
Deterministic evolutionary trajectories influence primary tumor growth: TRACERx renal
S Turajlic, H Xu, K Litchfield, A Rowan, S Horswell, T Chambers, ...
Cell 173 (3), 595-610. e11, 2018
2252018
Evolution and clinical impact of co-occurring genetic alterations in advanced-stage EGFR-mutant lung cancers
CM Blakely, TBK Watkins, W Wu, B Gini, JJ Chabon, CE McCoach, ...
Nature genetics 49 (12), 1693-1704, 2017
2252017
Fc effector function contributes to the activity of human anti-CTLA-4 antibodies
FA Vargas, AJS Furness, K Litchfield, K Joshi, R Rosenthal, E Ghorani, ...
Cancer cell 33 (4), 649-663. e4, 2018
2132018
Fc-optimized anti-CD25 depletes tumor-infiltrating regulatory T cells and synergizes with PD-1 blockade to eradicate established tumors
FA Vargas, AJS Furness, I Solomon, K Joshi, L Mekkaoui, MH Lesko, ...
Immunity 46 (4), 577-586, 2017
1902017
Tracking the genomic evolution of esophageal adenocarcinoma through neoadjuvant chemotherapy
N Murugaesu, GA Wilson, NJ Birkbak, TBK Watkins, N McGranahan, ...
Cancer discovery 5 (8), 821-831, 2015
1792015
Calcineurin signaling mediates activity-dependent relocation of the axon initial segment
MD Evans, RP Sammons, S Lebron, AS Dumitrescu, TBK Watkins, ...
Journal of Neuroscience 33 (16), 6950-6963, 2013
942013
Interplay between whole-genome doubling and the accumulation of deleterious alterations in cancer evolution
S López, EL Lim, S Horswell, K Haase, A Huebner, M Dietzen, ...
Nature Genetics 52 (3), 283-293, 2020
192020
A clonal expression biomarker associates with lung cancer mortality
D Biswas, NJ Birkbak, R Rosenthal, CT Hiley, EL Lim, K Papp, S Boeing, ...
Nature medicine 25 (10), 1540-1548, 2019
142019
The National Lung Matrix Trial of personalized therapy in lung cancer
G Middleton, P Fletcher, S Popat, J Savage, Y Summers, A Greystoke, ...
Nature 583 (7818), 807-812, 2020
132020
Corrigendum: Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution
C Abbosh, NJ Birkbak, GA Wilson, M Jamal-Hanjani, T Constantin, ...
Nature 554 (7691), 264-264, 2018
112018
Pervasive chromosomal instability and karyotype order in tumour evolution
TBK Watkins, EL Lim, M Petkovic, S Elizalde, NJ Birkbak, GA Wilson, ...
Nature 587 (7832), 126-132, 2020
72020
Expansion of airway basal epithelial cells from primary human non‐small cell lung cancer tumors
RE Hynds, A Ben Aissa, KHC Gowers, TBK Watkins, L Bosshard‐Carter, ...
International Journal of Cancer 143 (1), 160-166, 2018
62018
Representative sequencing: Unbiased sampling of solid tumor tissue
K Litchfield, S Stanislaw, L Spain, LL Gallegos, A Rowan, D Schnidrig, ...
Cell Reports 31 (5), 107550, 2020
52020
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