Makoto Nishiyama
Makoto Nishiyama
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FK228 (depsipeptide) as a natural prodrug that inhibits class I histone deacetylases
R Furumai, A Matsuyama, N Kobashi, KH Lee, M Nishiyama, H Nakajima, ...
Cancer research 62 (17), 4916-4921, 2002
Histone deacetylase as a new target for cancer chemotherapy
M Yoshida, R Furumai, M Nishiyama, Y Komatsu, N Nishino, S Horinouchi
Cancer chemotherapy and pharmacology 48, S20-S26, 2001
X-ray structure and site-directed mutagenesis of a nitrite reductase from Alcaligenes faecalis S-6: roles of two copper atoms in nitrite reduction
M Kukimoto, M Nishiyama, MEP Murphy, S Turley, ET Adman, ...
Biochemistry 33 (17), 5246-5252, 1994
Determinants of protein thermostability observed in the 1.9-. ANG. crystal structure of malate dehydrogenase from the thermophilic bacterium Thermus flavus
CA Kelly, M Nishiyama, Y Ohnishi, T Beppu, JJ Birktoft
Biochemistry 32 (15), 3913-3922, 1993
Primary structure of AfsR, a global regulatory protein for secondary metabolite formation in Streptomyces coelicolor A3(2)
S Horinouchi, M Kito, M Nishiyama, K Furuya, SK Hong, K Miyake, ...
Gene 95 (1), 49-56, 1990
Amidase coupled with low‐molecular‐mass nitrile hydratase from Rhodococcus rhodochrous J1: Sequencing and expression of the gene and purification and …
European Journal of Biochemistry 217 (1), 327-336, 1993
Cloning and characterization of genes responsible for metabolism of nitrile compounds from Pseudomonas chlororaphis B23
M Nishiyama, S Horinouchi, M Kobayashi, T Nagasawa, H Yamada, ...
Journal of bacteriology 173 (8), 2465-2472, 1991
Taking control over control: use of product sensing in single cells to remove flux control at key enzymes in biosynthesis pathways
G Schendzielorz, M Dippong, A Grunberger, D Kohlheyer, A Yoshida, ...
ACS synthetic biology 3 (1), 21-29, 2014
Cloning, nucleotide sequence and expression in Escherichia coli of two cobalt-containing nitrile hydratase genes from Rhodococcus rhodochrous J1
M Kobayashi, M Nishiyama, T Nagasawa, S Horinouchi, T Beppu, ...
Biochimica et Biophysica Acta (BBA)-Gene Structure and Expression 1129 (1 …, 1991
Catalytic roles for two water bridged residues (Asp-98 and His-255) in the active site of copper-containing nitrite reductase
MJ Boulanger, M Kukimoto, M Nishiyama, S Horinouchi, MEP Murphy
Journal of Biological Chemistry 275 (31), 23957-23964, 2000
Chemoenzymatic syntheses of prenylated aromatic small molecules using Streptomyces prenyltransferases with relaxed substrate specificities
T Kumano, SB Richard, JP Noel, M Nishiyama, T Kuzuyama
Bioorganic & medicinal chemistry 16 (17), 8117-8126, 2008
A prokaryotic gene cluster involved in synthesis of lysine through the amino adipate pathway: a key to the evolution of amino acid biosynthesis
H Nishida, M Nishiyama, N Kobashi, T Kosuge, T Hoshino, H Yamane
Genome Research 9 (12), 1175-1183, 1999
Primary structure of nitrile hydratase deduced from the nucleotide sequence of a Rhodococcus species and its expression in Escherichia coli
O Ikehata, M Nishiyama, S Horinouchi, T Beppu
European journal of biochemistry 181 (3), 563-570, 1989
Changes in the Acetylome and Succinylome of Bacillus subtilis in Response to Carbon Source
S Kosono, M Tamura, S Suzuki, Y Kawamura, A Yoshida, M Nishiyama, ...
PloS one 10 (6), e0131169, 2015
Molecular cloning and characterization of a cDNA encoding ent‐cassa‐12,15‐diene synthase, a putative diterpenoid phytoalexin biosynthetic enzyme, from …
EM Cho, A Okada, H Kenmoku, K Otomo, T Toyomasu, W Mitsuhashi, ...
The Plant Journal 37 (1), 1-8, 2004
Cloning and heterologous expression of the cyclooctatin biosynthetic gene cluster afford a diterpene cyclase and two p450 hydroxylases
SY Kim, P Zhao, M Igarashi, R Sawa, T Tomita, M Nishiyama, ...
Chemistry & biology 16 (7), 736-743, 2009
Biosynthesis of versipelostatin: identification of an enzyme-catalyzed [4+ 2]-cycloaddition required for macrocyclization of spirotetronate-containing polyketides
T Hashimoto, J Hashimoto, K Teruya, T Hirano, K Shin-ya, H Ikeda, H Liu, ...
Journal of the American Chemical Society 137 (2), 572-575, 2015
Structure of Alcaligenes faecalis nitrite reductase and a copper site mutant, M150E, that contains zinc
MEP Murphy, S Turley, M Kukimoto, M Nishiyama, S Horinouchi, H Sasaki, ...
Biochemistry 34 (38), 12107-12117, 1995
Nucleotide sequence of the streptothricin acetyltransferase gene from Streptomyces lavendulae and its expression in heterologous hosts
S Horinouchi, K Furuya, M Nishiyama, H Suzuki, T Beppu
Journal of bacteriology 169 (5), 1929-1937, 1987
Nucleotide sequence of the malate dehydrogenase gene of Thermus flavus and its mutation directing an increase in enzyme activity.
M Nishiyama, N Matsubara, K Yamamoto, S Iijima, T Uozumi, T Beppu
Journal of Biological Chemistry 261 (30), 14178-14183, 1986
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