Dan S Tawfik
Title
Cited by
Cited by
Year
Man-made cell-like compartments for molecular evolution
DS Tawfik, AD Griffiths
Nature biotechnology 16 (7), 652-656, 1998
12331998
Kemp elimination catalysts by computational enzyme design
D Röthlisberger, O Khersonsky, AM Wollacott, L Jiang, J DeChancie, ...
Nature 453 (7192), 190-195, 2008
11902008
The'evolvability'of promiscuous protein functions
A Aharoni, L Gaidukov, O Khersonsky, SMQ Gould, C Roodveldt, ...
Nature genetics 37 (1), 73-76, 2005
8112005
Antibody multispecificity mediated by conformational diversity
LC James, P Roversi, DS Tawfik
Science 299 (5611), 1362-1367, 2003
7142003
Protein dynamism and evolvability
N Tokuriki, DS Tawfik
Science 324 (5924), 203-207, 2009
7022009
Structure and evolution of the serum paraoxonase family of detoxifying and anti-atherosclerotic enzymes
M Harel, A Aharoni, L Gaidukov, B Brumshtein, O Khersonsky, R Meged, ...
Nature structural & molecular biology 11 (5), 412-419, 2004
6812004
Enzyme promiscuity: evolutionary and mechanistic aspects
O Khersonsky, C Roodveldt, DS Tawfik
Current opinion in chemical biology 10 (5), 498-508, 2006
6272006
The moderately efficient enzyme: evolutionary and physicochemical trends shaping enzyme parameters
A Bar-Even, E Noor, Y Savir, W Liebermeister, D Davidi, DS Tawfik, ...
Biochemistry 50 (21), 4402-4410, 2011
5952011
Stability effects of mutations and protein evolvability
N Tokuriki, DS Tawfik
Current opinion in structural biology 19 (5), 596-604, 2009
5812009
Conformational diversity and protein evolution–a 60-year-old hypothesis revisited
LC James, DS Tawfik
Trends in biochemical sciences 28 (7), 361-368, 2003
5442003
Miniaturising the laboratory in emulsion droplets
AD Griffiths, DS Tawfik
Trends in biotechnology 24 (9), 395-402, 2006
4632006
Amplification of complex gene libraries by emulsion PCR
R Williams, SG Peisajovich, OJ Miller, S Magdassi, DS Tawfik, AD Griffiths
Nature methods 3 (7), 545-550, 2006
4502006
Structure− reactivity studies of serum paraoxonase PON1 suggest that its native activity is lactonase
O Khersonsky, DS Tawfik
Biochemistry 44 (16), 6371-6382, 2005
4342005
How protein stability and new functions trade off
N Tokuriki, F Stricher, L Serrano, DS Tawfik
PLoS Comput Biol 4 (2), e1000002, 2008
4062008
In vitro sorting method
A Griffiths, D Tawfik
US Patent 6,489,103, 2002
373*2002
Directed evolution of an extremely fast phosphotriesterase by in vitro compartmentalization
AD Griffiths, DS Tawfik
The EMBO journal 22 (1), 24-35, 2003
3712003
Mutational effects and the evolution of new protein functions
M Soskine, DS Tawfik
Nature Reviews Genetics 11 (8), 572-582, 2010
3412010
Robustness–epistasis link shapes the fitness landscape of a randomly drifting protein
S Bershtein, M Segal, R Bekerman, N Tokuriki, DS Tawfik
Nature 444 (7121), 929-932, 2006
3412006
Directed evolution of mammalian paraoxonases PON1 and PON3 for bacterial expression and catalytic specialization
A Aharoni, L Gaidukov, S Yagur, L Toker, I Silman, DS Tawfik
Proceedings of the National Academy of Sciences 101 (2), 482-487, 2004
3222004
Chaperonin overexpression promotes genetic variation and enzyme evolution
N Tokuriki, DS Tawfik
Nature 459 (7247), 668-673, 2009
3072009
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