| Determination of the class and isoform selectivity of small-molecule histone deacetylase inhibitors N Khan, M Jeffers, S Kumar, C Hackett, F Boldog, N Khramtsov, X Qian, ... Biochemical Journal 409 (2), 581-589, 2008 | 860 | 2008 |
| Pharmacodynamic response and inhibition of growth of human tumor xenografts by the novel histone deacetylase inhibitor PXD101 JA Plumb, PW Finn, RJ Williams, MJ Bandara, MR Romero, CJ Watkins, ... Molecular cancer therapeutics 2 (8), 721-728, 2003 | 452 | 2003 |
| Quantitative proteomic analysis of post-translational modifications of human histones HC Beck, EC Nielsen, R Matthiesen, LH Jensen, M Sehested, P Finn, ... Molecular & Cellular Proteomics 5 (7), 1314-1325, 2006 | 234 | 2006 |
| Combined inhibition of DNA methylation and histone acetylation enhances gene re-expression and drug sensitivity in vivo N Steele, P Finn, R Brown, JA Plumb British journal of cancer 100 (5), 758-763, 2009 | 187 | 2009 |
| Pharmacophore discovery using the inductive logic programming system Progol P Finn, S Muggleton, D Page, A Srinivasan Machine Learning 30, 241-270, 1998 | 170 | 1998 |
| Carbamic acid compounds comprising an amide linkage as HDAC inhibitors A Amolins, V Andrianov, RM Bokaldere, K Dikovska, JES Duffy, PW Finn, ... US Patent 7,880,020, 2011 | 123* | 2011 |
| ElectroShape: fast molecular similarity calculations incorporating shape, chirality and electrostatics MS Armstrong, GM Morris, PW Finn, R Sharma, L Moretti, RI Cooper, ... Journal of computer-aided molecular design 24, 789-801, 2010 | 116 | 2010 |
| Carbamic acid compounds comprising an amide linkage as hdac inhibitors A Amolins, V Andrianov, RM Bokaldere, K Dikovska, JES Duffy, PW Finn, ... US Patent App. 12/983,971, 2011 | 111* | 2011 |
| Carbamic acid compounds comprising an amide linkage as HDAC inhibitors A Amolins, V Andrianov, RM Bokaldere, K Dikovska, JES Duffy, PW Finn, ... US Patent 7,569,724, 2009 | 110* | 2009 |
| RAPID: Randomized pharmacophore identification for drug design PW Finn, LE Kavraki, JC Latombe, M R, C Shelton, ... Computational Geometry: Theory and Applications 4 (10), 263-272, 1998 | 98 | 1998 |
| Carbamic acid compounds comprising a sulfonamide linkage as HDAC inhibitors CJ Watkins, MR Romero-Martin, KG Moore, J Ritchie, PW Finn, I Kalvinsh, ... US Patent 6,888,027, 2005 | 97 | 2005 |
| Ultrafast shape recognition: evaluating a new ligand-based virtual screening technology PJ Ballester, PW Finn, WG Richards Journal of Molecular Graphics and Modelling 27 (7), 836-845, 2009 | 96 | 2009 |
| The cell cycle, chromatin and cancer: mechanism-based therapeutics come of age F McLaughlin, P Finn, NB La Thangue Drug discovery today 8 (17), 793-802, 2003 | 87 | 2003 |
| Carbamic acid compounds comprising an ether linkage as HDAC inhibitors RM Bokaldere, JES Duffy, PW Finn, CJ Harris, I Kalvinsh, D Lolya, E Loza, ... US Patent 6,960,685, 2005 | 83* | 2005 |
| Computational approaches to drug design PW Finn, LE Kavraki Algorithmica 25, 347-371, 1999 | 78 | 1999 |
| Novel sulfonamide derivatives as inhibitors of histone deacetylase PW Finn, M Bandara, C Butcher, A Finn, R Hollinshead, N Khan, N Law, ... Helvetica Chimica Acta 88 (7), 1630-1657, 2005 | 75 | 2005 |
| Plasmodium subtilisin-like protease 1 (SUB1): insights into the active-site structure, specificity and function of a pan-malaria drug target C Withers-Martinez, C Suarez, S Fulle, S Kher, M Penzo, JP Ebejer, ... International journal for parasitology 42 (6), 597-612, 2012 | 62 | 2012 |
| A randomized kinematics‐based approach to pharmacophore‐constrained conformational search and database screening SM LaValle, PW Finn, LE Kavraki, JC Latombe Journal of Computational Chemistry 21 (9), 731-747, 2000 | 62 | 2000 |
| Epigenetic approaches to cancer therapy JA Plumb, N Steele, PW Finn, R Brown Biochemical Society Transactions 32 (6), 1095-1097, 2004 | 57 | 2004 |
| Are the physicochemical properties of antibacterial compounds really different from other drugs? JP Ebejer, MH Charlton, PW Finn Journal of cheminformatics 8, 1-9, 2016 | 54 | 2016 |
