Host-microbe co-metabolism dictates cancer drug efficacy in C. elegans TA Scott, LM Quintaneiro, P Norvaisas, PP Lui, MP Wilson, KY Leung, ... Cell 169 (3), 442-456. e18, 2017 | 237 | 2017 |
Host-microbe-drug-nutrient screen identifies bacterial effectors of metformin therapy R Pryor, P Norvaisas, G Marinos, L Best, LB Thingholm, LM Quintaneiro, ... Cell 178 (6), 1299-1312. e29, 2019 | 196 | 2019 |
Discovery and characterization of novel selective inhibitors of carbonic anhydrase IX V Dudutiene, J Matuliene, A Smirnov, DD Timm, A Zubriene, ... Journal of Medicinal Chemistry 57 (22), 9435-9446, 2014 | 92 | 2014 |
Intrinsic thermodynamics of 4-substituted-2, 3, 5, 6-tetrafluorobenzenesulfonamide binding to carbonic anhydrases by isothermal titration calorimetry A Zubrienė, J Smirnovienė, A Smirnov, V Morkūnaitė, V Michailovienė, ... Biophysical Chemistry 205, 51-65, 2015 | 60 | 2015 |
Fine-tuning autophagy maximises lifespan and is associated with changes in mitochondrial gene expression in Drosophila I Bjedov, HM Cochemé, A Foley, D Wieser, NS Woodling, JI Castillo-Quan, ... PLoS genetics 16 (11), e1009083, 2020 | 50 | 2020 |
Thermodynamics of cationic and anionic surfactant interaction P Norvaišas, V Petrauskas, D Matulis The Journal of Physical Chemistry B 116 (7), 2138-2144, 2012 | 37 | 2012 |
The role of payload hydrophobicity in nanotherapeutic pharmacokinetics P Norvaisas, A Ziemys Journal of pharmaceutical sciences 103 (7), 2147-2156, 2014 | 22 | 2014 |
WormJam: A consensus C. elegans Metabolic Reconstruction and Metabolomics Community and Workshop Series J Hastings, A Mains, M Artal-Sanz, S Bergmann, BP Braeckman, J Bundy, ... Worm 6 (2), e1373939, 2017 | 17 | 2017 |
Revisiting Santa Rosalia to unfold a degeneracy of classic models of speciation P Norvaišas, E Kisdi The American Naturalist 180 (3), 388-393, 2012 | 14 | 2012 |
High pressure spectrofluorimetry–a tool to determine protein-ligand binding volume G Skvarnavičius, Z Toleikis, M Grigaliūnas, J Smirnovienė, P Norvaišas, ... Journal of Physics: Conference Series 950 (4), 042001, 2017 | 9 | 2017 |
Pharmacology in the age of the holobiont P Norvaisas, F Cabreiro Current Opinion in Systems Biology 10, 34-42, 2018 | 7 | 2018 |
Hydrascreen: A generalizable structure-based deep learning approach to drug discovery A Prat, HA Aty, G Kamuntavičius, T Paquet, P Norvaišas, P Gasparotto, ... arXiv preprint arXiv:2311.12814, 2023 | 2 | 2023 |
The protein kinase promiscuities in the cancer-preventive mechanisms of NSAIDs P Norvaisas, D Chan, K Yokoi, B Dave, A Ziemys European Journal of Cancer Prevention 25 (1), 77-84, 2016 | 2 | 2016 |
Prediction and analysis of drug delivery systems: from drug-vector compatibility to release kinetics P Norvaisas, M Kojic, M Milosevic, A Ziemys Scientifically speaking September, 14-15, 2013 | 2 | 2013 |
Benchmarking ML in ADMET predictions: the practical impact of feature representations in ligand-based models G Kamuntavičius, T Paquet, O Bastas, D Šalkauskas, A Prat, HA Aty, ... | | 2024 |
Benchmarking ML in ADMET predictions: A focus on hypothesis testing practices G Kamuntavičius, O Bastas, T Paquet, P Norvaišas, R Tal | | 2024 |
Accelerated Hit Identification with Target Evaluation, Deep Learning and Automated Labs: Prospective Validation in IRAK1 G Kamuntavičius, A Prat, T Paquet, O Bastas, HA Aty, Q Sun, ... | | 2024 |
Prospective Validation of HydraScreen: Virtual Screening and Hit Identification in IRAK1 G Kamuntavičius, A Prat, T Paquet, O Bastas, HA Aty, Q Sun, D Rines, ... | | 2023 |
System and method for feedback-driven automated drug discovery P Norvaisas, R Tal, Z Jocys, CD Knuff, A Prat, G Kamuntavicius, HA Aty, ... US Patent App. 17/845,813, 2022 | | 2022 |
Discovery of a Novel Allosteric Inhibitor PK-188 Targeting New Delhi Metallo-β Lactamases. P Kavaliauskas, D Tondi, L Cendron, B Grybaite, K Anusevicius, ... 32nd European Congress of Clinical Microbiology and Infectious Diseases., 2022 | | 2022 |