Követés
David Thornton
David Thornton
E-mail megerősítve itt: manchester.ac.uk - Kezdőlap
Cím
Hivatkozott rá
Hivatkozott rá
Év
Structure and function of the polymeric mucins in airways mucus
DJ Thornton, K Rousseau, MA McGuckin
Annu. Rev. Physiol. 70 (1), 459-486, 2008
9422008
Aberrant mucin assembly in mice causes endoplasmic reticulum stress and spontaneous inflammation resembling ulcerative colitis
CK Heazlewood, MC Cook, R Eri, GR Price, SB Tauro, D Taupin, ...
PLoS medicine 5 (3), e54, 2008
8262008
Muc5b is required for airway defence
MG Roy, A Livraghi-Butrico, AA Fletcher, MM McElwee, SE Evans, ...
Nature 505 (7483), 412-416, 2014
7712014
From mucins to mucus: toward a more coherent understanding of this essential barrier
DJ Thornton, JK Sheehan
Proceedings of the American Thoracic Society 1 (1), 54-61, 2004
4832004
Heterogeneity of airways mucus: variations in the amounts and glycoforms of the major oligomeric mucins MUC5AC and MUC5B
S Kirkham, JK Sheehan, D Knight, PS Richardson, DJ Thornton
Biochemical Journal 361 (3), 537-546, 2002
4362002
Muc5ac: a critical component mediating the rejection of enteric nematodes
SZ Hasnain, CM Evans, M Roy, AL Gallagher, KN Kindrachuk, L Barron, ...
Journal of Experimental Medicine 208 (5), 893-900, 2011
3262011
Respiratory mucins: identification of core proteins and glycoforms
DJ Thornton, I Carlstedt, M Howard, PL Devine, MR Price, JK Sheehan
Biochemical Journal 316 (3), 967-975, 1996
2411996
Identification of two glycoforms of the MUC5B mucin in human respiratory mucus: evidence for a cysteine-rich sequence repeated within the molecule
DJ Thornton, M Howard, N Khan, JK Sheehan
Journal of Biological Chemistry 272 (14), 9561-9566, 1997
2341997
Mucin gene deficiency in mice impairs host resistance to an enteric parasitic infection
SZ Hasnain, H Wang, JE Ghia, N Haq, Y Deng, A Velcich, RK Grencis, ...
Gastroenterology 138 (5), 1763-1771. e5, 2010
2272010
Tracheobronchial air-liquid interface cell culture: a model for innate mucosal defense of the upper airways?
M Kesimer, S Kirkham, RJ Pickles, AG Henderson, NE Alexis, G DeMaria, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 296 (1 …, 2009
2122009
Mucins: the frontline defence of the lung
C Ridley, DJ Thornton
Biochemical Society Transactions 46 (5), 1099-1106, 2018
1972018
Calcium-dependent protein interactions in MUC5B provide reversible cross-links in salivary mucus
BDE Raynal, TE Hardingham, JK Sheehan, DJ Thornton
Journal of Biological Chemistry 278 (31), 28703-28710, 2003
1892003
Salivary mucin MG1 is comprised almost entirely of different glycosylated forms of the MUC5B gene product
DJ Thornton, N Khan, R Mehrotra, M Howard, JK Sheehan, E Veerman, ...
Glycobiology 9 (3), 293-302, 1999
1791999
The lung environment controls alveolar macrophage metabolism and responsiveness in type 2 inflammation
FR Svedberg, SL Brown, MZ Krauss, L Campbell, C Sharpe, M Clausen, ...
Nature immunology 20 (5), 571-580, 2019
1732019
MUC5B is the major mucin in the gel phase of sputum in chronic obstructive pulmonary disease
S Kirkham, U Kolsum, K Rousseau, D Singh, J Vestbo, DJ Thornton
American journal of respiratory and critical care medicine 178 (10), 1033-1039, 2008
1662008
Identification in vitreous and molecular cloning of opticin, a novel member of the family of leucine-rich repeat proteins of the extracellular matrix
AJ Reardon, M Le Goff, MD Briggs, D McLeod, JK Sheehan, DJ Thornton, ...
Journal of Biological Chemistry 275 (3), 2123-2129, 2000
1592000
Analysis of respiratory mucus glycoproteins in asthma: a detailed study from a patient who died in status asthmaticus.
JK Sheehan, PS Richardson, DC Fung, M Howard, DJ Thornton
American journal of respiratory cell and molecular biology 13 (6), 748-756, 1995
1561995
Mucus glycoproteins from ‘normal’human tracheobronchial secretion
DJ Thornton, JR Davies, M Kraayenbrink, PS Richardson, JK Sheehan, ...
Biochemical journal 265 (1), 179-186, 1990
1521990
Particle tracking microrheology of purified gastrointestinal mucins
P Georgiades, PDA Pudney, DJ Thornton, TA Waigh
Biopolymers 101 (4), 366-377, 2014
1492014
Cystic fibrosis: an inherited disease affecting mucin-producing organs
C Ehre, C Ridley, DJ Thornton
The international journal of biochemistry & cell biology 52, 136-145, 2014
1482014
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