Követés
Kinga Nyíri
Kinga Nyíri
Young investigator Budapest University of Technology and Economics
E-mail megerősítve itt: enzim.hu
Cím
Hivatkozott rá
Hivatkozott rá
Év
Impact of lipophilic efficiency on compound quality
A Tarcsay, K Nyíri, GM Keserű
Journal of medicinal chemistry 55 (3), 1252-1260, 2012
1862012
Highly potent dUTPase inhibition by a bacterial repressor protein reveals a novel mechanism for gene expression control
JE Szabo, V Németh, V Papp-Kádár, K Nyíri, I Leveles, AA Bendes, ...
Nucleic acids research 42 (19), 11912-11920, 2014
592014
Cross-species inhibition of dUTPase via the Staphylococcal Stl protein perturbs dNTP pool and colony formation in Mycobacterium
R Hirmondó, JE Szabó, K Nyíri, S Tarjányi, P Dobrotka, J Tóth, ...
DNA repair 30, 21-27, 2015
342015
Structure and enzymatic mechanism of a moonlighting dUTPase
I Leveles, V Németh, JE Szabó, V Harmat, K Nyíri, ÁÁ Bendes, ...
Acta Crystallographica Section D: Biological Crystallography 69 (12), 2298-2308, 2013
342013
Evidence-based structural model of the staphylococcal repressor protein: separation of functions into different domains
K Nyíri, B Kőhegyi, A Micsonai, J Kardos, BG Vertessy
PLoS One 10 (9), e0139086, 2015
232015
Structural model of human dUTPase in complex with a novel proteinaceous inhibitor
K Nyíri, HDT Mertens, B Tihanyi, GN Nagy, B Kőhegyi, J Matejka, ...
Scientific Reports 8 (1), 4326, 2018
222018
Assessment of tractable cysteines for covalent targeting by screening covalent fragments
L Petri, P Ábrányi‐Balogh, I Tímea, G Pálfy, A Perczel, D Knez, M Hrast, ...
ChemBioChem 22 (4), 743-753, 2021
182021
Structure-based inhibitor design of mutant RAS proteins—a paradigm shift
K Nyíri, G Koppány, BG Vértessy
Cancer and Metastasis Reviews 39, 1091-1105, 2020
182020
On the stability of six-membered-ring carbenes and silylenes
K Nyiri, T Veszprémi
Organometallics 28 (20), 5909-5914, 2009
172009
The mechanism and energetics of insertion reactions of silylenes
K Nyíri, T Szilvási, T Veszprémi
Dalton Transactions 39 (39), 9347-9352, 2010
162010
Perturbation of genome integrity to fight pathogenic microorganisms
K Nyíri, BG Vértessy
Biochimica et Biophysica Acta (BBA)-General Subjects 1861 (1), 3593-3612, 2017
132017
In Vitro Analysis of Predicted DNA-Binding Sites for the Stl Repressor of the Staphylococcus aureus SaPIBov1 Pathogenicity Island
V Papp-Kádár, JE Szabó, K Nyíri, BG Vertessy
PLoS One 11 (7), e0158793, 2016
132016
Exploring the role of the phage-specific insert of bacteriophage Φ11 dUTPase
K Nyíri, V Papp-Kádár, JE Szabó, V Németh, BG Vértessy
Structural Chemistry 26, 1425-1432, 2015
132015
Exploiting a phage-bacterium interaction system as a molecular switch to decipher macromolecular interactions in the living cell
ÉV Surányi, R Hírmondó, K Nyíri, S Tarjányi, B Kőhegyi, J Tóth, ...
Viruses 10 (4), 168, 2018
122018
Unique Insertion Mechanisms of Bis-dehydro-β-diketiminato Silylene
T Szilvási, K Nyíri, T Veszprémi
Organometallics 30 (20), 5344-5351, 2011
122011
HDX and native mass spectrometry reveals the different structural basis for interaction of the staphylococcal pathogenicity island repressor Stl with dimeric and trimeric phage …
K Nyíri, MJ Harris, J Matejka, O Ozohanics, K Vékey, AJ Borysik, ...
Biomolecules 9 (9), 488, 2019
92019
Mechanism-Based Redesign of GAP to Activate Oncogenic Ras
D Berta, S Gehrke, K Nyíri, BG Vértessy, E Rosta
Journal of the American Chemical Society 145 (37), 20302-20310, 2023
52023
Covalent fragment mapping of KRasG12C revealed novel chemotypes with in vivo potency
Z Orgován, N Péczka, L Petri, P Ábrányi-Balogh, I Ranđelović, S Tóth, ...
European Journal of Medicinal Chemistry 250, 115212, 2023
22023
Correction to impact of lipophilic efficiency on compound quality
A Tarcsay, K Nyíri, GM Keserű
Journal of Medicinal Chemistry 56 (7), 3120-3120, 2013
22013
Gluing GAP to RAS Mutants: A New Approach to an Old Problem in Cancer Drug Development
I Ranđelović, K Nyíri, G Koppány, M Baranyi, J Tóvári, A Kigyós, J Tímár, ...
International Journal of Molecular Sciences 25 (5), 2572, 2024
12024
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