James Eshleman
James Eshleman
Professor of Patholgy, Oncology, Johns Hopkins University
E-mail megerősítve itt: jhmi.edu
Cím
Hivatkozott rá
Hivatkozott rá
Év
PD-1 blockade in tumors with mismatch-repair deficiency
DT Le, JN Uram, H Wang, BR Bartlett, H Kemberling, AD Eyring, ...
New England Journal of Medicine 372 (26), 2509-2520, 2015
64442015
A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination …
CR Boland, SN Thibodeau, SR Hamilton, D Sidransky, JR Eshleman, ...
Cancer research 58 (22), 5248-5257, 1998
46571998
Core signaling pathways in human pancreatic cancers revealed by global genomic analyses
S Jones, X Zhang, DW Parsons, JCH Lin, RJ Leary, P Angenendt, ...
science 321 (5897), 1801-1806, 2008
40062008
Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade
DT Le, JN Durham, KN Smith, H Wang, BR Bartlett, LK Aulakh, S Lu, ...
Science 357 (6349), 409-413, 2017
34212017
Distant metastasis occurs late during the genetic evolution of pancreatic cancer
S Yachida, S Jones, I Bozic, T Antal, R Leary, B Fu, M Kamiyama, ...
Nature 467 (7319), 1114-1117, 2010
24042010
Genomic analyses identify molecular subtypes of pancreatic cancer
P Bailey, DK Chang, K Nones, AL Johns, AM Patch, MC Gingras, ...
Nature 531 (7592), 47-52, 2016
18832016
Whole genomes redefine the mutational landscape of pancreatic cancer
N Waddell, M Pajic, AM Patch, DK Chang, KS Kassahn, P Bailey, ...
Nature 518 (7540), 495-501, 2015
18052015
Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes
AV Biankin, N Waddell, KS Kassahn, MC Gingras, LB Muthuswamy, ...
Nature 491 (7424), 399-405, 2012
17202012
Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours
DM Berman, SS Karhadkar, A Maitra, RM De Oca, MR Gerstenblith, ...
Nature 425 (6960), 846-851, 2003
15362003
DPC4 gene status of the primary carcinoma correlates with patterns of failure in patients with pancreatic cancer
CA Iacobuzio-Donahue, B Fu, S Yachida, M Luo, H Abe, CM Henderson, ...
Journal of clinical oncology 27 (11), 1806, 2009
9612009
Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene
S Jones, RH Hruban, M Kamiyama, M Borges, X Zhang, DW Parsons, ...
Science 324 (5924), 217-217, 2009
8352009
Recurrent GNAS mutations define an unexpected pathway for pancreatic cyst development
J Wu, H Matthaei, A Maitra, M Dal Molin, LD Wood, JR Eshleman, ...
Science translational medicine 3 (92), 92ra66-92ra66, 2011
7312011
Whole-exome sequencing of neoplastic cysts of the pancreas reveals recurrent mutations in components of ubiquitin-dependent pathways
J Wu, Y Jiao, M Dal Molin, A Maitra, RF De Wilde, LD Wood, JR Eshleman, ...
Proceedings of the National Academy of Sciences 108 (52), 21188-21193, 2011
5422011
Exploration of global gene expression patterns in pancreatic adenocarcinoma using cDNA microarrays
CA Iacobuzio-Donahue, A Maitra, M Olsen, AW Lowe, NT Van Heek, ...
The American journal of pathology 162 (4), 1151-1162, 2003
5262003
Microsatellite instability as a biomarker for PD-1 blockade
JC Dudley, MT Lin, DT Le, JR Eshleman
Clinical Cancer Research 22 (4), 813-820, 2016
5082016
Comparison of Sanger sequencing, pyrosequencing, and melting curve analysis for the detection of KRAS mutations: diagnostic and clinical implications
AC Tsiatis, A Norris-Kirby, RG Rich, MJ Hafez, CD Gocke, JR Eshleman, ...
The Journal of Molecular Diagnostics 12 (4), 425-432, 2010
4792010
Haploinsufficiency of telomerase reverse transcriptase leads to anticipation in autosomal dominant dyskeratosis congenita
M Armanios, JL Chen, YPC Chang, RA Brodsky, A Hawkins, CA Griffin, ...
Proceedings of the National Academy of Sciences 102 (44), 15960-15964, 2005
4752005
ATM mutations in patients with hereditary pancreatic cancer
NJ Roberts, Y Jiao, J Yu, L Kopelovich, GM Petersen, ML Bondy, ...
Cancer discovery 2 (1), 41-46, 2012
4652012
An in vivo platform for translational drug development in pancreatic cancer
B Rubio-Viqueira, A Jimeno, G Cusatis, X Zhang, C Iacobuzio-Donahue, ...
Clinical cancer research 12 (15), 4652-4661, 2006
4282006
SMAD4 gene mutations are associated with poor prognosis in pancreatic cancer
A Blackford, OK Serrano, CL Wolfgang, G Parmigiani, S Jones, X Zhang, ...
Clinical cancer research 15 (14), 4674-4679, 2009
3542009
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