Thomas R. Cox

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Alison GartlandThe University of SheffieldVerified email at sheffield.ac.uk
Michael PapanicolaouAlbert Einstein College of MedicineVerified email at einsteinmed.edu
Holly BarkerThe Walter and Eliza Hall Institute of Medical Research, Melbourne, AustraliaVerified email at wehi.edu.au
Dr. Rune LindingHumboldt-Universität zu BerlinVerified email at hu-berlin.de
Yibin KangWarner-Lambert/Parke-Davis Professor of Molecular Biology, Princeton UniversityVerified email at princeton.edu
Joan ChangResearch Fellow (Principal Investigator), University of ManchesterVerified email at manchester.ac.uk
Lara PerrymanUniversity of CopenhagenVerified email at bric.ku.dk
Hector PeinadoSpanish National Cancer Research Center (CNIO)Verified email at cnio.es
Jacqueline BrombergMemorial Sloan KetteringVerified email at mskcc.org
Bruno Costa-SilvaChampalimaud FoundationVerified email at research.fchampalimaud.org
Rosandra KaplanNational Institutes of Health/ National Cancer InstituteVerified email at mail.nih.gov
Irina MateiWeill Cornell MedicineVerified email at med.cornell.edu
Monica NicolauUniversity of Freiburg: Freiburg im Breisgau, DEVerified email at uniklinik-freiburg.de
Quynh-Thu LeProfessor, stanford universityVerified email at stanford.edu
Albert KoongMD Anderson Cancer CenterVerified email at mdanderson.org
Edward HortonAutomation ScientistVerified email at novonordisk.com
Lena WullkopfScientist and Team Lead Transcriptomics and Genomics, Discovery Unit, Immatics BiotechnologiesVerified email at immatics.com
David R. CroucherGarvan Institute of Medical ResearchVerified email at garvan.org.au
Brooke A. PereiraPost-doctoral Research Officer, Garvan Institute of Medical ResearchVerified email at garvan.org.au
Freja Albjerg VenningUCB NordicVerified email at ucb.com

Thomas R. Cox

Garvan Institute of Medical Research

Verified email at garvan.org.au - Homepage

Extracellular Matrix Lysyl Oxidases Metastasis Cancer


Title Sort by citations Sort by year Sort by title	Cited by Cited by	Year
Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer TR Cox, JT Erler Disease models & mechanisms 4 (2), 165-178, 2011	1743	2011
Pre-metastatic niches: organ-specific homes for metastases H Peinado, H Zhang, IR Matei, B Costa-Silva, A Hoshino, G Rodrigues, ... Nature Reviews Cancer 17 (5), 302-317, 2017	1598	2017
Hypoxia-induced lysyl oxidase is a critical mediator of bone marrow cell recruitment to form the premetastatic niche JT Erler, KL Bennewith, TR Cox, G Lang, D Bird, A Koong, QT Le, ... Cancer cell 15 (1), 35-44, 2009	1368	2009
The rationale for targeting the LOX family in cancer HE Barker, TR Cox, JT Erler Nature Reviews Cancer 12 (8), 540-552, 2012	600	2012
LOX-mediated collagen crosslinking is responsible for fibrosis-enhanced metastasis TR Cox, D Bird, AM Baker, HE Barker, MWY Ho, G Lang, JT Erler Cancer research 73 (6), 1721-1732, 2013	579	2013
RETRACTED ARTICLE: The hypoxic cancer secretome induces pre-metastatic bone lesions through lysyl oxidase TR Cox, RMH Rumney, EM Schoof, L Perryman, AM Høye, A Agrawal, ... Nature 522 (7554), 106-110, 2015	558	2015
The matrix in cancer TR Cox Nature Reviews Cancer 21 (4), 217-238, 2021	514	2021
Targeting stromal remodeling and cancer stem cell plasticity overcomes chemoresistance in triple negative breast cancer AS Cazet, MN Hui, BL Elsworth, SZ Wu, D Roden, CL Chan, JN Skhinas, ... Nature communications 9 (1), 2897, 2018	357	2018
Lysyl oxidase enzymatic function increases stiffness to drive colorectal cancer progression through FAK AM Baker, D Bird, G Lang, TR Cox, JT Erler Oncogene 32 (14), 1863-1868, 2013	340	2013
LOXL2-mediated matrix remodeling in metastasis and mammary gland involution HE Barker, J Chang, TR Cox, G Lang, D Bird, M Nicolau, HR Evans, ... Cancer research 71 (5), 1561-1572, 2011	319	2011
Stromal cell diversity associated with immune evasion in human triple‐negative breast cancer SZ Wu, DL Roden, C Wang, H Holliday, K Harvey, AS Cazet, KJ Murphy, ... The EMBO journal 39 (19), e104063, 2020	256	2020
CAF subpopulations: a new reservoir of stromal targets in pancreatic cancer BA Pereira, C Vennin, M Papanicolaou, CR Chambers, D Herrmann, ... Trends in cancer 5 (11), 724-741, 2019	250	2019
Lamin A/C is a risk biomarker in colorectal cancer ND Willis, TR Cox, SF Rahman-Casans, K Smits, SA Przyborski, ... PloS one 3 (8), e2988, 2008	245	2008
Transient tissue priming via ROCK inhibition uncouples pancreatic cancer progression, sensitivity to chemotherapy, and metastasis C Vennin, VT Chin, SC Warren, MC Lucas, D Herrmann, A Magenau, ... Science translational medicine 9 (384), eaai8504, 2017	238	2017
The role of lysyl oxidase in SRC-dependent proliferation and metastasis of colorectal cancer AM Baker, TR Cox, D Bird, G Lang, GI Murray, XF Sun, SM Southall, ... Journal of the National Cancer Institute 103 (5), 407-424, 2011	228	2011
Cancer cells’ ability to mechanically adjust to extracellular matrix stiffness correlates with their invasive potential L Wullkopf, AKV West, N Leijnse, TR Cox, CD Madsen, LB Oddershede, ... Molecular biology of the cell 29 (20), 2378-2385, 2018	214	2018
CAF hierarchy driven by pancreatic cancer cell p53-status creates a pro-metastatic and chemoresistant environment via perlecan C Vennin, P Mélénec, R Rouet, M Nobis, AS Cazet, KJ Murphy, ... Nature communications 10 (1), 3637, 2019	199	2019
Reshaping the tumor stroma for treatment of pancreatic cancer C Vennin, KJ Murphy, JP Morton, TR Cox, M Pajic, P Timpson Gastroenterology 154 (4), 820-838, 2018	197	2018
Kinome-wide decoding of network-attacking mutations rewiring cancer signaling P Creixell, EM Schoof, CD Simpson, J Longden, CJ Miller, HJ Lou, ... Cell 163 (1), 202-217, 2015	183	2015
Molecular pathways: connecting fibrosis and solid tumor metastasis TR Cox, JT Erler Clinical Cancer Research 20 (14), 3637-3643, 2014	172	2014

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