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Orsolya Barabas
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Mechanism of IS200/IS605 family DNA transposases: activation and transposon-directed target site selection
O Barabas, DR Ronning, C Guynet, AB Hickman, B Ton-Hoang, ...
Cell 132 (2), 208-220, 2008
1422008
Structural Insights into the Catalytic Mechanism of Phosphate Ester Hydrolysis by dUTPase*♦
O Barabás, V Pongrácz, J Kovári, M Wilmanns, BG Vértessy
Journal of Biological Chemistry 279 (41), 42907-42915, 2004
1162004
Helicobacter pylori's plasticity zones are novel transposable elements
D Kersulyte, WK Lee, D Subramaniam, S Anant, P Herrera, L Cabrera, ...
PloS one 4 (9), e6859, 2009
1102009
Active site closure facilitates juxtaposition of reactant atoms for initiation of catalysis by human dUTPase
B Varga, O Barabás, J Kovári, J Tóth, É Hunyadi-Gulyás, É Klement, ...
FEBS letters 581 (24), 4783-4788, 2007
892007
Active site of mycobacterial dUTPase: structural characteristics and a built-in sensor
B Varga, O Barabás, E Takács, N Nagy, P Nagy, BG Vértessy
Biochemical and biophysical research communications 373 (1), 8-13, 2008
832008
A highly soluble Sleeping Beauty transposase improves control of gene insertion
I Querques, A Mades, C Zuliani, C Miskey, M Alb, E Grueso, M Machwirth, ...
Nature biotechnology 37 (12), 1502-1512, 2019
792019
In vitro reconstitution of a single-stranded transposition mechanism of IS608
C Guynet, AB Hickman, O Barabas, F Dyda, M Chandler, B Ton-Hoang
Molecular cell 29 (3), 302-312, 2008
712008
An integrated approach for genome annotation of the eukaryotic thermophile Chaetomium thermophilum
T Bock, WH Chen, A Ori, N Malik, N Silva-Martin, J Huerta-Cepas, ...
Nucleic acids research 42 (22), 13525-13533, 2014
662014
Crystal structure of the primary piRNA biogenesis factor Zucchini reveals similarity to the bacterial PLD endonuclease Nuc
F Voigt, M Reuter, A Kasaruho, EC Schulz, RS Pillai, O Barabas
Rna 18 (12), 2128-2134, 2012
662012
Flexible segments modulate co-folding of dUTPase and nucleocapsid proteins
V Nemeth-Pongracz, O Barabas, M Fuxreiter, I Simon, I Pichová, ...
Nucleic acids research 35 (2), 495-505, 2007
652007
Altered active site flexibility and a structural metal-binding site in eukaryotic dUTPase: kinetic characterization, folding, and crystallographic studies of the homotrimeric …
J Kovári, O Barabás, E Takács, A Békési, Z Dubrovay, V Pongrácz, ...
Journal of Biological Chemistry 279 (17), 17932-17944, 2004
622004
Sleeping Beauty transposase structure allows rational design of hyperactive variants for genetic engineering
F Voigt, L Wiedemann, C Zuliani, I Querques, A Sebe, L Mátés, Z Izsvák, ...
Nature communications 7 (1), 1-8, 2016
572016
Revisiting the mechanism of the autoactivation of the complement protease C1r in the C1 complex: Structure of the active catalytic region of C1r
J Kardos, V Harmat, A Palló, O Barabás, K Szilágyi, L Gráf, ...
Molecular immunology 45 (6), 1752-1760, 2008
522008
DNA recognition and the precleavage state during single‐stranded DNA transposition in D. radiodurans
AB Hickman, JA James, O Barabas, C Pasternak, B Ton‐Hoang, ...
The EMBO journal 29 (22), 3840-3852, 2010
472010
Transposase-DNA complex structures reveal mechanisms for conjugative transposition of antibiotic resistance
A Rubio-Cosials, EC Schulz, L Lambertsen, G Smyshlyaev, ...
Cell 173 (1), 208-220. e20, 2018
442018
Methylene substitution at the α–β bridging position within the phosphate chain of dUDP profoundly perturbs ligand accommodation into the dUTPase active site
J Kovari, O Barabás, B Varga, A Békési, F Tölgyesi, J Fidy, J Nagy, ...
Proteins: Structure, Function, and Bioinformatics 71 (1), 308-319, 2008
442008
Molecular shape and prominent role of β-strand swapping in organization of dUTPase oligomers
E Takács, O Barabás, MV Petoukhov, DI Svergun, BG Vértessy
FEBS letters 583 (5), 865-871, 2009
402009
Landscape of mobile genetic elements and their antibiotic resistance cargo in prokaryotic genomes
S Khedkar, G Smyshlyaev, I Letunic, OM Maistrenko, LP Coelho, ...
Nucleic Acids Research 50 (6), 3155-3168, 2022
392022
The USTC co-opts an ancient machinery to drive piRNA transcription in C. elegans
C Weng, J Kosalka, AC Berkyurek, P Stempor, X Feng, H Mao, C Zeng, ...
Genes & development 33 (1-2), 90-102, 2019
392019
Sequence analysis of tyrosine recombinases allows annotation of mobile genetic elements in prokaryotic genomes
G Smyshlyaev, A Bateman, O Barabas
Molecular systems biology 17 (5), e9880, 2021
342021
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