EBSeq: an empirical Bayes hierarchical model for inference in RNA-seq experiments N Leng, JA Dawson, JA Thomson, V Ruotti, AI Rissman, BMG Smits, ... Bioinformatics 29 (8), 1035-1043, 2013 | 1232 | 2013 |
Atezolizumab versus chemotherapy in patients with platinum-treated locally advanced or metastatic urothelial carcinoma (IMvigor211): a multicentre, open-label, phase 3 … T Powles, I Durán, MS Van der Heijden, Y Loriot, NJ Vogelzang, ... The Lancet 391 (10122), 748-757, 2018 | 1182 | 2018 |
Single-cell RNA-seq reveals novel regulators of human embryonic stem cell differentiation to definitive endoderm LF Chu, N Leng, J Zhang, Z Hou, D Mamott, DT Vereide, J Choi, ... Genome biology 17, 1-20, 2016 | 327 | 2016 |
SCnorm: robust normalization of single-cell RNA-seq data R Bacher, LF Chu, N Leng, AP Gasch, JA Thomson, RM Stewart, ... Nature methods 14 (6), 584-586, 2017 | 269 | 2017 |
Molecular subsets in renal cancer determine outcome to checkpoint and angiogenesis blockade RJ Motzer, R Banchereau, H Hamidi, T Powles, D McDermott, MB Atkins, ... Cancer cell 38 (6), 803-817. e4, 2020 | 215 | 2020 |
High systemic and tumor-associated IL-8 correlates with reduced clinical benefit of PD-L1 blockade KC Yuen, LF Liu, V Gupta, S Madireddi, S Keerthivasan, C Li, ... Nature medicine 26 (5), 693-698, 2020 | 191 | 2020 |
Oscope identifies oscillatory genes in unsynchronized single-cell RNA-seq experiments N Leng, LF Chu, C Barry, Y Li, J Choi, X Li, P Jiang, RM Stewart, ... Nature methods 12 (10), 947-950, 2015 | 154 | 2015 |
Comparative RNA-seq analysis in the unsequenced axolotl: the oncogene burst highlights early gene expression in the blastema R Stewart, CA Rascón, S Tian, J Nie, C Barry, LF Chu, H Ardalani, ... PLoS computational biology 9 (3), e1002936, 2013 | 131 | 2013 |
Functional characterization of human pluripotent stem cell-derived arterial endothelial cells J Zhang, LF Chu, Z Hou, MP Schwartz, T Hacker, V Vickerman, ... Proceedings of the National Academy of Sciences 114 (30), E6072-E6078, 2017 | 120 | 2017 |
The Osteoblast to Osteocyte Transition: Epigenetic Changes and Response to the Vitamin D3 Hormone HC St. John, KA Bishop, MB Meyer, NA Benkusky, N Leng, C Kendziorski, ... Molecular endocrinology 28 (7), 1150-1165, 2014 | 100 | 2014 |
EBSeq-HMM: a Bayesian approach for identifying gene-expression changes in ordered RNA-seq experiments N Leng, Y Li, BE McIntosh, BK Nguyen, B Duffin, S Tian, JA Thomson, ... Bioinformatics 31 (16), 2614-2622, 2015 | 96 | 2015 |
A Vehicle-based Measurement Framework for Enhancing Whitespace Spectrum Databases T Zhang, N Leng, S Banerjee MobiCom 14, 2014 | 91 | 2014 |
Molecular correlates differentiate response to atezolizumab (atezo)+ bevacizumab (bev) vs sunitinib (sun): results from a phase III study (IMmotion151) in untreated metastatic … BI Rini, M Huseni, MB Atkins, DF McDermott, TB Powles, B Escudier, ... Annals of Oncology 29, viii724-viii725, 2018 | 87 | 2018 |
Molecular determinants of response to PD-L1 blockade across tumor types R Banchereau, N Leng, O Zill, E Sokol, G Liu, D Pavlick, S Maund, LF Liu, ... Nature communications 12 (1), 3969, 2021 | 58 | 2021 |
A Wireless Spectrum Analyzer in Your Pocket T Zhang, A Patro, N Leng, S Banerjee Hotmobile, 2015 | 56 | 2015 |
The transcription factor Nfatc2 regulates β-cell proliferation and genes associated with type 2 diabetes in mouse and human islets MP Keller, PK Paul, ME Rabaglia, DS Stapleton, KL Schueler, AT Broman, ... PLoS genetics 12 (12), e1006466, 2016 | 44 | 2016 |
Collaborative rewiring of the pluripotency network by chromatin and signalling modulating pathways KA Tran, SA Jackson, ZPG Olufs, NZ Zaidan, N Leng, C Kendziorski, ... Nature communications 6 (1), 6188, 2015 | 42 | 2015 |
Atezolizumab (atezo) vs. chemotherapy (chemo) in platinum-treated locally advanced or metastatic urothelial carcinoma (mUC): Immune biomarkers, tumor mutational burden (TMB … T Powles, Y Loriot, A Ravaud, NJ Vogelzang, I Duran, M Retz, ... Journal of clinical Oncology 36 (6_suppl), 409-409, 2018 | 39 | 2018 |
Histone chaperone ASF1B promotes human β-cell proliferation via recruitment of histone H3.3 PK Paul, ME Rabaglia, CY Wang, DS Stapleton, N Leng, C Kendziorski, ... Cell Cycle 15 (23), 3191-3202, 2016 | 38 | 2016 |
Analysis of embryonic development in the unsequenced axolotl: Waves of transcriptomic upheaval and stability P Jiang, JD Nelson, N Leng, M Collins, S Swanson, CN Dewey, ... Developmental biology 426 (2), 143-154, 2017 | 37 | 2017 |