| Structure-based discovery of opioid analgesics with reduced side effects A Manglik, H Lin, DK Aryal, JD McCorvy, D Dengler, G Corder, A Levit, ... Nature 537 (7619), 185-190, 2016 | 955 | 2016 |
| Cre‐dependent DREADD (designer receptors exclusively activated by designer drugs) mice H Zhu, DK Aryal, RHJ Olsen, DJ Urban, A Swearingen, S Forbes, BL Roth, ... genesis 54 (8), 439-446, 2016 | 178 | 2016 |
| Deficiency of asparagine synthetase causes congenital microcephaly and a progressive form of encephalopathy EK Ruzzo, JM Capo-Chichi, B Ben-Zeev, D Chitayat, H Mao, AL Pappas, ... Neuron 80 (2), 429-441, 2013 | 176 | 2013 |
| Elucidation of the behavioral program and neuronal network encoded by dorsal raphe serotonergic neurons DJ Urban, H Zhu, CA Marcinkiewcz, M Michaelides, H Oshibuchi, D Rhea, ... Neuropsychopharmacology 41 (5), 1404-1415, 2016 | 151 | 2016 |
| Antioxidative effects of quercetin-glycosides isolated from the flower buds of Tussilago farfara L. MR Kim, JY Lee, HH Lee, DK Aryal, YG Kim, SK Kim, ER Woo, KW Kang Food and chemical toxicology 44 (8), 1299-1307, 2006 | 146 | 2006 |
| Spine pruning drives antipsychotic-sensitive locomotion via circuit control of striatal dopamine. HYSHS Il Hwan Kim, Dipendra K Aryal, Mark A Rossi, Bence Racz, Namsoo Kim ... Nature Neuroscience, 2015 | 145 | 2015 |
| Disrupted iron homeostasis causes dopaminergic neurodegeneration in mice P Matak, A Matak, S Moustafa, DK Aryal, EJ Benner, W Wetsel, ... Proceedings of the National Academy of Sciences 113 (13), 3428-3435, 2016 | 125 | 2016 |
| GPR171 is a hypothalamic G protein-coupled receptor for BigLEN, a neuropeptide involved in feeding I Gomes, DK Aryal, JH Wardman, A Gupta, K Gagnidze, RM Rodriguiz, ... Proceedings of the National Academy of Sciences 110 (40), 16211-16216, 2013 | 83 | 2013 |
| Neurotrophic factor-α1 prevents stress-induced depression through enhancement of neurogenesis and is activated by rosiglitazone Y Cheng, RM Rodriguiz, SRK Murthy, V Senatorov, E Thouennon, ... Molecular psychiatry 20 (6), 744-754, 2015 | 77 | 2015 |
| Differential regulation of MeCP2 phosphorylation in the CNS by dopamine and serotonin AN Hutchinson, JV Deng, DK Aryal, WC Wetsel, AE West Neuropsychopharmacology 37 (2), 321-337, 2012 | 40 | 2012 |
| Distinct neuronal populations in the basolateral and central amygdala are activated with acute pain, conditioned fear, and fear-conditioned analgesia RK Butler, S Ehling, M Barbar, J Thomas, MA Hughes, CE Smith, ... Neuroscience letters 661, 11-17, 2017 | 28 | 2017 |
| Pharmacokinetics of amitriptyline and one of its metabolites, nortriptyline, in rats: little contribution of considerable hepatic first-pass effect to low bioavailability of … SK Bae, KH Yang, DK Aryal, YG Kim, MG Lee Journal of pharmaceutical sciences 98 (4), 1587-1601, 2009 | 27 | 2009 |
| Peptidylglycine α‐amidating monooxygenase heterozygosity alters brain copper handling with region specificity ED Gaier, MB Miller, M Ralle, D Aryal, WC Wetsel, RE Mains, BA Eipper Journal of neurochemistry 127 (5), 605-619, 2013 | 25 | 2013 |
| Targeted deletion of GD3 synthase protects against MPTP‐induced neurodegeneration Y Akkhawattanangkul, P Maiti, Y Xue, D Aryal, WC Wetsel, D Hamilton, ... Genes, Brain and Behavior 16 (5), 522-536, 2017 | 23 | 2017 |
| G protein-coupled receptor kinase-2 (GRK-2) regulates serotonin metabolism through the monoamine oxidase AMX-2 in Caenorhabditis elegans J Wang, J Luo, DK Aryal, WC Wetsel, R Nass, JL Benovic Journal of Biological Chemistry 292 (14), 5943-5956, 2017 | 15 | 2017 |
| Preclinical toxicity evaluation of a novel immunotoxin, D2C7-(scdsFv)-PE38KDEL, administered via intracerebral convection-enhanced delivery in rats X Bao, V Chandramohan, RP Reynolds, JN Norton, WC Wetsel, ... Investigational new drugs 34, 149-158, 2016 | 15 | 2016 |
| 7, 7′-Dihydroxy bursehernin inhibits the expression of inducible nitric oxide synthase through NF-κB DNA binding suppression YR Pokharel, QH Liu, DK Aryal, YG Kim, ER Woo, KW Kang Nitric Oxide 16 (2), 274-285, 2007 | 13 | 2007 |
| Pharmacokinetics of venlafaxine and its major metabolite o-desmethylvenlafaxine in freely moving mice using automated dosing/sampling system B Aryal, D Aryal, EJ Kim, HG Kim Indian Journal of Pharmacology 44 (1), 20-25, 2012 | 9 | 2012 |
| Effects of R. glutinosa and E. senticosus on postmenopausal osteoporosis SY Oh, DK Aryal, YG Kim, HG Kim The Korean Journal of Physiology and Pharmacology 11 (3), 121-127, 2007 | 4 | 2007 |
| Mice lacking proSAAS display alterations in emotion, consummatory behavior and circadian entrainment DK Aryal, RM Rodriguiz, NL Nguyen, MW Pease, DJ Morgan, J Pintar, ... Genes, Brain and Behavior 21 (7), e12827, 2022 | 3 | 2022 |
BL RothDepartment of Pharmacology, University of North Carolina Medical SchoolVerified email at med.unc.edu
