Követés
Stanislav Gobec
Stanislav Gobec
Faculty of Pharmacy, University of Ljubljana
E-mail megerősítve itt: ffa.uni-lj.si - Kezdőlap
Cím
Hivatkozott rá
Hivatkozott rá
Év
Cytoplasmic steps of peptidoglycan biosynthesis
H Barreteau, A Kovač, A Boniface, M Sova, S Gobec, D Blanot
FEMS microbiology reviews 32 (2), 168-207, 2008
9352008
Discovery, biological evaluation, and crystal structure of a novel nanomolar selective butyrylcholinesterase inhibitor
B Brus, U Kosak, S Turk, A Pislar, N Coquelle, J Kos, J Stojan, JP Colletier, ...
Journal of medicinal chemistry 57 (19), 8167-8179, 2014
2812014
Inhibitors of cathepsin B
R Frlan, S Gobec
Current medicinal chemistry 13 (19), 2309-2327, 2006
1782006
The magic of crystal structure-based inhibitor optimization: development of a butyrylcholinesterase inhibitor with picomolar affinity and in vivo activity
U Kosak, B Brus, D Knez, S Zakelj, J Trontelj, A Pislar, R Sink, M Jukic, ...
Journal of medicinal chemistry 61 (1), 119-139, 2018
1552018
False positives in the early stages of drug discovery
R Sink, S Gobec, S Pecar, A Zega
Current medicinal chemistry 17 (34), 4231-4255, 2010
1532010
Development of an in-vivo active reversible butyrylcholinesterase inhibitor
U Koąak, B Brus, D Knez, R ©ink, S ®akelj, J Trontelj, A Piąlar, J ©lenc, ...
Scientific reports 6 (1), 39495, 2016
1522016
Endocrine Disruptome An Open Source Prediction Tool for Assessing Endocrine Disruption Potential through Nuclear Receptor Binding
K Kolšek, J Mavri, M Sollner Dolenc, S Gobec, S Turk
Journal of chemical information and modeling 54 (4), 1254-1267, 2014
1382014
Discovery of novel 5-benzylidenerhodanine and 5-benzylidenethiazolidine-2, 4-dione inhibitors of MurD ligase
N Zidar, T Tomašić, R Šink, V Rupnik, A Kovac, S Turk, D Patin, ...
Journal of medicinal chemistry 53 (18), 6584-6594, 2010
1272010
A road map for prioritizing warheads for cysteine targeting covalent inhibitors
P Abranyi-Balogh, L Petri, T Imre, P Szijj, A Scarpino, M Hrast, A Mitrović, ...
European journal of medicinal chemistry 160, 94-107, 2018
1252018
Inhibitors of the peptidoglycan biosynthesis enzymes MurA-F
M Hrast, I Sosič, R ©ink, S Gobec
Bioorganic chemistry 55, 2-15, 2014
1152014
Inhibitors of 17β-hydroxysteroid dehydrogenase type 1
S Gobec, P Brozic, TL Rizner
Current medicinal chemistry 15 (2), 137-150, 2008
1122008
Structural characterization and biological evaluation of a clioquinol–ruthenium complex with copper-independent antileukaemic activity
M Gobec, J Kljun, I Sosič, I Mlinarič-Raąčan, M Urąič, S Gobec, I Turel
Dalton Transactions 43 (24), 9045-9051, 2014
1082014
Novel mechanism of cathepsin B inhibition by antibiotic nitroxoline and related compounds
B Mirković, M Renko, S Turk, I Sosič, Z Jevnikar, N Obermajer, D Turk, ...
ChemMedChem 6 (8), 1351, 2011
1052011
Structural and functional characterization of enantiomeric glutamic acid derivatives as potential transition state analogue inhibitors of MurD ligase
M Kotnik, J Humljan, C Contreras-Martel, M Oblak, K Kristan, M Hervé, ...
Journal of molecular biology 370 (1), 107-115, 2007
1012007
Antifungal activity of cinnamic acid derivatives involves inhibition of benzoate 4‐hydroxylase (CYP53)
B Koroąec, M Sova, S Turk, N Kraąevec, M Novak, L Lah, J Stojan, ...
Journal of applied microbiology 116 (4), 955-966, 2014
1002014
5‐Benzylidenethiazolidin‐4‐ones as multitarget inhibitors of bacterial Mur ligases
T Tomaąić, N Zidar, A Kovač, S Turk, M Simčič, D Blanot, ...
ChemMedChem: Chemistry Enabling Drug Discovery 5 (2), 286-295, 2010
952010
Design, synthesis and biological evaluation of new phthalimide and saccharin derivatives with alicyclic amines targeting cholinesterases, beta-secretase and amyloid beta …
D Panek, A Więckowska, T Wichur, M Bajda, J Godyń, J Jończyk, K Mika, ...
European journal of medicinal chemistry 125, 676-695, 2017
942017
Novel Naphthalene-N-sulfonyl-d-glutamic Acid Derivatives as Inhibitors of MurD, a Key Peptidoglycan Biosynthesis Enzyme,
J Humljan, M Kotnik, C Contreras-Martel, D Blanot, U Urleb, A Dessen, ...
Journal of medicinal chemistry 51 (23), 7486-7494, 2008
922008
Multi-target-directed ligands for treating Alzheimer's disease: Butyrylcholinesterase inhibitors displaying antioxidant and neuroprotective activities
D Knez, N Coquelle, A Piąlar, S ®akelj, M Jukič, M Sova, J Mravljak, ...
European journal of medicinal chemistry 156, 598-617, 2018
902018
LiSiCA: a software for ligand-based virtual screening and its application for the discovery of butyrylcholinesterase inhibitors
S Lešnik, T Štular, B Brus, D Knez, S Gobec, D Janezic, J Konc
Journal of chemical information and modeling 55 (8), 1521-1528, 2015
902015
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