| Mechanism of blebbistatin inhibition of myosin II M Kovács, J Tóth, C Hetényi, A Málnási-Csizmadia, JR Sellers Journal of Biological Chemistry 279 (34), 35557-35563, 2004 | 1150 | 2004 |
| Keeping uracil out of DNA: physiological role, structure and catalytic mechanism of dUTPases BG Vértessy, J Tóth Accounts of chemical research 42 (1), 97-106, 2009 | 279 | 2009 |
| Kinetic mechanism of human dUTPase, an essential nucleotide pyrophosphatase enzyme J Tóth, B Varga, M Kovács, A Málnási-Csizmadia, BG Vértessy Journal of Biological Chemistry 282 (46), 33572-33582, 2007 | 91 | 2007 |
| Active site closure facilitates juxtaposition of reactant atoms for initiation of catalysis by human dUTPase B Varga, O Barabás, J Kovári, J Tóth, É Hunyadi-Gulyás, É Klement, ... FEBS letters 581 (24), 4783-4788, 2007 | 85 | 2007 |
| Aromatic stacking between nucleobase and enzyme promotes phosphate ester hydrolysis in dUTPase I Pecsi, I Leveles, V Harmat, BG Vertessy, J Toth Nucleic acids research 38 (20), 7179-7186, 2010 | 71 | 2010 |
| The dUTPase enzyme is essential in Mycobacterium smegmatis I Pecsi, R Hirmondo, AC Brown, A Lopata, T Parish, BG Vertessy, J Tóth PloS one 7 (5), e37461, 2012 | 67 | 2012 |
| Myosin V from Drosophila reveals diversity of motor mechanisms within the myosin V family J Tóth, M Kovács, F Wang, L Nyitray, JR Sellers Journal of Biological Chemistry 280 (34), 30594-30603, 2005 | 65 | 2005 |
| Highly potent dUTPase inhibition by a bacterial repressor protein reveals a novel mechanism for gene expression control JE Szabo, V Németh, V Papp-Kádár, K Nyíri, I Leveles, AA Bendes, ... Nucleic acids research 42 (19), 11912-11920, 2014 | 54 | 2014 |
| Switch 1 mutation S217A converts myosin V into a low duty ratio motor E Forgacs, T Sakamoto, S Cartwright, B Belknap, M Kovács, J Tóth, ... Journal of Biological Chemistry 284 (4), 2138-2149, 2009 | 51 | 2009 |
| Shared developmental roles and transcriptional control of autophagy and apoptosis in Caenorhabditis elegans P Erdélyi, É Borsos, K Takács-Vellai, T Kovács, AL Kovács, T Sigmond, ... Journal of cell science 124 (9), 1510-1518, 2011 | 46 | 2011 |
| Nucleotide pyrophosphatase employs a P-loop-like motif to enhance catalytic power and NDP/NTP discrimination I Pécsi, JE Szabó, SD Adams, I Simon, JR Sellers, BG Vértessy, J Tóth Proceedings of the National Academy of Sciences 108 (35), 14437-14442, 2011 | 45 | 2011 |
| Absolute Stereochemical Assignment and Fluorescence Tuning of the Small Molecule Tool,(–)‐Blebbistatin C Lucas‐Lopez, S Patterson, T Blum, AF Straight, J Toth, AMZ Slawin, ... European journal of organic chemistry 2005 (9), 1736-1740, 2005 | 45 | 2005 |
| Phosphorylation adjacent to the nuclear localization signal of human dUTPase abolishes nuclear import: structural and mechanistic insights G Rona, M Marfori, M Borsos, I Scheer, E Takács, J Toth, F Babos, ... Acta Crystallographica Section D: Biological Crystallography 69 (12), 2495-2505, 2013 | 41 | 2013 |
| Structural characterization of arginine fingers: identification of an arginine finger for the pyrophosphatase dUTPases GN Nagy, R Suardíaz, A Lopata, O Ozohanics, K Vékey, BR Brooks, ... Journal of the American Chemical Society 138 (45), 15035-15045, 2016 | 39 | 2016 |
| Proteins with Complex Architecture as Potential Targets for Drug Design: A Case Study of Mycobacterium tuberculosis B Mészáros, J Tóth, BG Vértessy, Z Dosztányi, I Simon PLoS computational biology 7 (7), e1002118, 2011 | 37 | 2011 |
| Cellular response to efficient dUTPase RNAi silencing in stable HeLa cell lines perturbs expression levels of genes involved in thymidylate metabolism G Merényi, J Kovári, J Tóth, E Takács, I Zagyva, A Erdei, BG Vértessy Nucleosides, Nucleotides and Nucleic Acids 30 (6), 369-390, 2011 | 37 | 2011 |
| Mutations decouple proton transfer from phosphate cleavage in the dutpase catalytic reaction A Lopata, PG Jambrina, PK Sharma, BR Brooks, J Toth, BG Vertessy, ... Acs Catalysis 5 (6), 3225-3237, 2015 | 34 | 2015 |
| Selective perturbation of the myosin recovery stroke by point mutations at the base of the lever arm affects ATP hydrolysis and phosphate release A Maélnaési-Csizmadia, J Toéth, DS Pearson, C Heteényi, L Nyitray, ... Journal of Biological Chemistry 282 (24), 17658-17664, 2007 | 34 | 2007 |
| Cross-species inhibition of dUTPase via the Staphylococcal Stl protein perturbs dNTP pool and colony formation in Mycobacterium R Hirmondó, JE Szabó, K Nyíri, S Tarjányi, P Dobrotka, J Tóth, ... DNA repair 30, 21-27, 2015 | 31 | 2015 |
| Structure and enzymatic mechanism of a moonlighting dUTPase I Leveles, V Németh, JE Szabó, V Harmat, K Nyíri, AA Bendes, ... Acta Crystallographica Section D: Biological Crystallography 69 (12), 2298-2308, 2013 | 31 | 2013 |
Beata G. VertessyProfessor, EI RCNS HAS, BME HungaryVerified email at mail.bme.hu
