Chymotrypsin C (CTRC) variants that diminish activity or secretion are associated with chronic pancreatitis J Rosendahl, H Witt, R Szmola, E Bhatia, B Ózsvári, O Landt, HU Schulz, ... Nature genetics 40 (1), 78-82, 2008 | 526 | 2008 |
Cys‐scanning mutagenesis: a novel approach to structure—function relationships in polytopic membrane proteins S Frillingos, M Sahin‐Tóth, J Wu, HR Kaback The FASEB Journal 12 (13), 1281-1299, 1998 | 430 | 1998 |
The kamikaze approach to membrane transport HR Kaback, M Sahin-Tóth, AB Weinglass Nature reviews Molecular cell biology 2 (8), 610-620, 2001 | 350 | 2001 |
Variants in CPA1 are strongly associated with early onset chronic pancreatitis H Witt, S Beer, J Rosendahl, JM Chen, GR Chandak, A Masamune, ... Nature genetics 45 (10), 1216-1220, 2013 | 334 | 2013 |
Genetics, cell biology, and pathophysiology of pancreatitis J Mayerle, M Sendler, E Hegyi, G Beyer, MM Lerch, M Sahin-Tóth Gastroenterology 156 (7), 1951-1968. e1, 2019 | 319 | 2019 |
A degradation-sensitive anionic trypsinogen (PRSS2) variant protects against chronic pancreatitis H Witt, M Sahin-Tóth, O Landt, JM Chen, T Kähne, JPH Drenth, Z Kukor, ... Nature genetics 38 (6), 668-673, 2006 | 288 | 2006 |
Prospective, multicentre, nationwide clinical data from 600 cases of acute pancreatitis A Párniczky, B Kui, A Szentesi, A Balázs, Á Szűcs, D Mosztbacher, ... PloS one 11 (10), e0165309, 2016 | 273 | 2016 |
Gain-of-function mutations associated with hereditary pancreatitis enhance autoactivation of human cationic trypsinogen M Sahin-Tóth, M Tóth Biochemical and biophysical research communications 278 (2), 286-289, 2000 | 263 | 2000 |
Alcohol disrupts levels and function of the cystic fibrosis transmembrane conductance regulator to promote development of pancreatitis J Maléth, A Balázs, P Pallagi, Z Balla, B Kui, M Katona, L Judák, I Németh, ... Gastroenterology 148 (2), 427-439. e16, 2015 | 219 | 2015 |
Chymotrypsin C (caldecrin) promotes degradation of human cationic trypsin: identity with Rinderknecht's enzyme Y R Szmola, M Sahin-Tóth Proceedings of the National Academy of Sciences 104 (27), 11227-11232, 2007 | 205 | 2007 |
Genetic risk in chronic pancreatitis: the trypsin-dependent pathway E Hegyi, M Sahin-Tóth Digestive diseases and sciences 62 (7), 1692-1701, 2017 | 184 | 2017 |
Hereditary pancreatitis caused by mutation‐induced misfolding of human cationic trypsinogen: a novel disease mechanism É Kereszturi, R Szmola, Z Kukor, P Simon, F Ulrich Weiss, MM Lerch, ... Human mutation 30 (4), 575-582, 2009 | 183 | 2009 |
Human cationic trypsinogen: role of Asn-21 in zymogen activation and implications in hereditary pancreatitis M Sahin-Tóth Journal of Biological Chemistry 275 (30), 22750-22755, 2000 | 182 | 2000 |
Hereditary pancreatitis caused by a novel PRSS1 mutation (Arg-122→ Cys) that alters autoactivation and autodegradation of cationic trypsinogen P Simon, FU Weiss, M Sahin-Tóth, M Parry, O Nayler, B Lenfers, ... Journal of Biological Chemistry 277 (7), 5404-5410, 2002 | 181 | 2002 |
Autoantibodies against the exocrine pancreas in autoimmune pancreatitis: gene and protein expression profiling and immunoassays identify pancreatic enzymes as a major target of … JM Löhr, R Faissner, D Koczan, P Bewerunge, C Bassi, B Brors, R Eils, ... Official journal of the American College of Gastroenterology| ACG 105 (9 …, 2010 | 180 | 2010 |
Human mesotrypsin is a unique digestive protease specialized for the degradation of trypsin inhibitors R Szmola, Z Kukor, M Sahin-Tóth Journal of Biological Chemistry 278 (49), 48580-48589, 2003 | 176 | 2003 |
Functional interactions between putative intramembrane charged residues in the lactose permease of Escherichia coli. M Sahin-Toth, RL Dunten, A Gonzalez, HR Kaback Proceedings of the National Academy of Sciences 89 (21), 10547-10551, 1992 | 166 | 1992 |
Properties of permease dimer, a fusion protein containing two lactose permease molecules from Escherichia coli. M Sahin-Toth, MC Lawrence, HR Kaback Proceedings of the National Academy of Sciences 91 (12), 5421-5425, 1994 | 164 | 1994 |
Cathepsin L inactivates human trypsinogen, whereas cathepsin L-deletion reduces the severity of pancreatitis in mice T Wartmann, J Mayerle, T Kähne, M Sahin–Tóth, M Ruthenbürger, ... Gastroenterology 138 (2), 726-737, 2010 | 163 | 2010 |
Mutations of human cationic trypsinogen (PRSS1) and chronic pancreatitis N Teich, J Rosendahl, M Tóth, J Mössner, M Sahin‐Tóth Human mutation 27 (8), 721-730, 2006 | 160 | 2006 |