| Stimulation of the vagus nerve attenuates macrophage activation by activating the Jak2-STAT3 signaling pathway WJ de Jonge, EP van der Zanden, FO The, MF Bijlsma, DJ van Westerloo, ... Nature immunology 6 (8), 844-851, 2005 | 1042 | 2005 |
| Poor-prognosis colon cancer is defined by a molecularly distinct subtype and develops from serrated precursor lesions F De Sousa E Melo, X Wang, M Jansen, E Fessler, A Trinh, ... Nature medicine 19 (5), 614-618, 2013 | 895 | 2013 |
| Laparoscopic versus open pancreatoduodenectomy for pancreatic or periampullary tumours (LEOPARD-2): a multicentre, patient-blinded, randomised controlled phase 2/3 trial J Van Hilst, T de Rooij, K Bosscha, DJ Brinkman, S van Dieren, ... The lancet Gastroenterology & hepatology 4 (3), 199-207, 2019 | 598 | 2019 |
| Repression of smoothened by patched-dependent (pro-) vitamin D3 secretion MF Bijlsma, CA Spek, D Zivkovic, S van de Water, F Rezaee, ... PLoS biology 4 (8), e232, 2006 | 407 | 2006 |
| Common variation at 2p13. 3, 3q29, 7p13 and 17q25. 1 associated with susceptibility to pancreatic cancer EJ Childs, E Mocci, D Campa, PM Bracci, S Gallinger, M Goggins, D Li, ... Nature genetics 47 (8), 911-916, 2015 | 275 | 2015 |
| The coagulant response in sepsis and inflammation M Levi Hämostaseologie 30 (01), 10-16, 2010 | 253 | 2010 |
| Neoadjuvant chemoradiotherapy combined with atezolizumab for resectable esophageal adenocarcinoma: a single-arm phase II feasibility trial (PERFECT) T Van Den Ende, NC De Clercq, MI van Berge Henegouwen, SS Gisbertz, ... Clinical Cancer Research 27 (12), 3351-3359, 2021 | 208 | 2021 |
| Stromal-derived interleukin 6 drives epithelial-to-mesenchymal transition and therapy resistance in esophageal adenocarcinoma EA Ebbing, AP van der Zalm, A Steins, A Creemers, S Hermsen, ... Proceedings of the National Academy of Sciences 116 (6), 2237-2242, 2019 | 179 | 2019 |
| Apc-mutant cells act as supercompetitors in intestinal tumour initiation SM van Neerven, NE de Groot, LE Nijman, BP Scicluna, MS van Driel, ... Nature 594 (7863), 436-441, 2021 | 173 | 2021 |
| Stem cell functionality is microenvironmentally defined during tumour expansion and therapy response in colon cancer KJ Lenos, DM Miedema, SC Lodestijn, LE Nijman, T van den Bosch, ... Nature cell biology 20 (10), 1193-1202, 2018 | 170 | 2018 |
| Molecular subtyping of cancer: current status and moving toward clinical applications L Zhao, VHF Lee, MK Ng, H Yan, MF Bijlsma Briefings in bioinformatics 20 (2), 572-584, 2019 | 152 | 2019 |
| Molecular subtypes in cancers of the gastrointestinal tract MF Bijlsma, A Sadanandam, P Tan, L Vermeulen Nature reviews Gastroenterology & hepatology 14 (6), 333-342, 2017 | 137 | 2017 |
| Hedgehog: an unusual signal transducer MF Bijlsma, CA Spek, MP Peppelenbosch Bioessays 26 (4), 387-394, 2004 | 129 | 2004 |
| The hepatic pre-metastatic niche in pancreatic ductal adenocarcinoma DS Houg, MF Bijlsma Molecular cancer 17 (1), 95, 2018 | 127 | 2018 |
| Sonic hedgehog induces transcription-independent cytoskeletal rearrangement and migration regulated by arachidonate metabolites MF Bijlsma, KS Borensztajn, H Roelink, MP Peppelenbosch, CA Spek Cellular signalling 19 (12), 2596-2604, 2007 | 123 | 2007 |
| ITGA5 inhibition in pancreatic stellate cells attenuates desmoplasia and potentiates efficacy of chemotherapy in pancreatic cancer PR Kuninty, R Bansal, SWL De Geus, DF Mardhian, J Schnittert, ... Science advances 5 (9), eaax2770, 2019 | 115 | 2019 |
| Three new pancreatic cancer susceptibility signals identified on chromosomes 1q32. 1, 5p15. 33 and 8q24. 21 M Zhang, Z Wang, O Obazee, J Jia, EJ Childs, J Hoskins, G Figlioli, ... Oncotarget 7 (41), 66328, 2016 | 114 | 2016 |
| Hypoxia induces a hedgehog response mediated by HIF‐1α MF Bijlsma, AP Groot, JP Oduro, RJ Franken, SHHF Schoenmakers, ... Journal of cellular and molecular medicine 13 (8b), 2053-2060, 2009 | 112 | 2009 |
| Key biological processes driving metastatic spread of pancreatic cancer as identified by multi-omics studies TYS Le Large, MF Bijlsma, G Kazemier, HWM Van Laarhoven, ... Seminars in cancer biology 44, 153-169, 2017 | 105 | 2017 |
| BAG3 promotes pancreatic ductal adenocarcinoma growth by activating stromal macrophages A Rosati, A Basile, R D’Auria, M d’Avenia, M De Marco, A Falco, M Festa, ... Nature communications 6 (1), 8695, 2015 | 98 | 2015 |
Hanneke van LaarhovenVerified email at amc.uva.nl
