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Patrick Donahue
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The COMET toolkit for composing customizable genetic programs in mammalian cells
PS Donahue, JW Draut, JJ Muldoon, HI Edelstein, N Bagheri, JN Leonard
Nature communications 11 (1), 779, 2020
632020
Elucidation and refinement of synthetic receptor mechanisms
HI Edelstein, PS Donahue, JJ Muldoon, AK Kang, TB Dolberg, ...
Synthetic Biology 5 (1), ysaa017, 2020
262020
Model-guided design of mammalian genetic programs
JJ Muldoon, V Kandula, M Hong, PS Donahue, JD Boucher, N Bagheri, ...
Science Advances 7 (8), eabe9375, 2021
232021
Building with intent: technologies and principles for engineering mammalian cell-based therapies to sense and respond
JJ Muldoon, PS Donahue, TB Dolberg, JN Leonard
Current opinion in biomedical engineering 4, 127-133, 2017
102017
Thermodynamic signature of DNA damage: Characterization of DNA with a 5-hydroxy-2′-deoxycytidine· 2′-deoxyguanosine base pair
M Ganguly, MW Szulik, PS Donahue, K Clancy, MP Stone, B Gold
Biochemistry 51 (9), 2018-2027, 2012
102012
Reframing cell therapy for cancer
TB Dolberg, PS Donahue, JN Leonard
Nature Chemical Biology 14 (3), 204-205, 2018
72018
Engineered mamalian genetic circuits and methods of using the same
JN Leonard, JJ Muldoon, PS Donahue
US Patent App. 18/026,734, 2023
2023
Comparative evaluation of synthetic cytokines for enhancing production and performance of NK92 cell-based therapies
S Deol, PS Donahue, RE Mitrut, IJ Hammitt-Kess, J Ahn, B Zhang, ...
GEN biotechnology 2 (3), 228-246, 2023
2023
A platform of composable mammalian elements of transcription (comet)
JN Leonard, PS Donahue
US Patent App. 16/496,140, 2020
2020
Enabling Cell-Based Therapies Through Environmental Sensing and Signal Processing
PS Donahue
Northwestern University, 2020
2020
Computational Design of Synthetic Genetic Programs That Exhibit Pulse Dynamics
M Hong, J Muldoon, PS Donahue, JW Draut, J Leonard
2018 AIChE Annual Meeting, 2018
2018
Comet: A Novel Transcription Toolbox for Engineering Cellular Therapies
PS Donahue, JW Draut, JJ Muldoon, JN Leonard
MOLECULAR THERAPY 26 (5), 76-76, 2018
2018
Characterization of 5-hydroxycytosine opposite guanine and adenine in DNA
MW Szulik, P Donahue, MP Stone
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 246, 2013
2013
Structural and thermodynamic aspects of cytosine oxidation in DNA
MW Szulik, M Ganguly, PS Donahue, K Clancy, I Khutsishivili, B Gold, ...
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 244, 2012
2012
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Articles 1–14