The human chitotriosidase gene nature of inherited enzyme deficiency RG Boot, GH Renkema, M Verhoek, A Strijland, J Bliek, ... Journal of Biological Chemistry 273 (40), 25680-25685, 1998 | 504 | 1998 |
Cloning of a cDNA encoding chitotriosidase, a human chitinase produced by macrophages RG Boot, GH Renkema, A Strijland, AJ van Zonneveld, JMFG Aerts Journal of Biological Chemistry 270 (44), 26252-26256, 1995 | 500 | 1995 |
Chitotriosidase, a chitinase, and the 39‐kDa human cartilage glycoprotein, a chitin‐binding lectin, are homologues of family 18 glycosyl hydrolases secreted by human macrophages GH Renkema, RG Boot, FL Au, WE Donker‐Koopman, A Strijland, ... European Journal of Biochemistry 251 (1‐2), 504-509, 1998 | 479 | 1998 |
Strong induction of members of the chitinase family of proteins in atherosclerosis: chitotriosidase and human cartilage gp-39 expressed in lesion macrophages RG Boot, TAE van Achterberg, BE van Aken, GH Renkema, MJHM Jacobs, ... Arteriosclerosis, thrombosis, and vascular biology 19 (3), 687-694, 1999 | 438 | 1999 |
Purification and characterization of human chitotriosidase, a novel member of the chitinase family of proteins GH Renkema, RG Boot, AO Muijsers, WE Donker-Koopman, JMFG Aerts Journal of Biological Chemistry 270 (5), 2198-2202, 1995 | 407 | 1995 |
Characterization of human phagocyte-derived chitotriosidase, a component of innate immunity M Van Eijk, CPAA van Roomen, GH Renkema, AP Bussink, L Andrews, ... International immunology 17 (11), 1505-1512, 2005 | 364 | 2005 |
Generation of specific deoxynojirimycin-type inhibitors of the non-lysosomal glucosylceramidase HS Overkleeft, GH Renkema, J Neele, P Vianello, IO Hung, A Strijland, ... Journal of Biological Chemistry 273 (41), 26522-26527, 1998 | 263 | 1998 |
Statin-Induced Myopathy Is Associated with Mitochondrial Complex III Inhibition TJJ Schirris, GH Renkema, T Ritschel, NC Voermans, A Bilos, ... Cell Metabolism 22 (3), 399-407, 2015 | 229 | 2015 |
Mutations in the phospholipid remodeling gene SERAC1 impair mitochondrial function and intracellular cholesterol trafficking and cause dystonia and deafness SB Wortmann, FM Vaz, T Gardeitchik, LELM Vissers, GH Renkema, ... Nature genetics 44 (7), 797-802, 2012 | 227 | 2012 |
Interactions of HIV-1 NEF with cellular signal transducing proteins GH Renkema, K Saksela Frontiers in Bioscience-Landmark 5 (3), 268-283, 2000 | 207 | 2000 |
Synthesis, sorting, and processing into distinct isoforms of human macrophage chitotriosidase GH Renkema, RG Boot, A Strijland, WE Donker‐Koopman, ... European journal of biochemistry 244 (2), 279-285, 1997 | 202 | 1997 |
High-throughput phosphotyrosine profiling using SH2 domains K Machida, CM Thompson, K Dierck, K Jablonowski, S Kärkkäinen, B Liu, ... Molecular cell 26 (6), 899-915, 2007 | 197 | 2007 |
Transglycosidase activity of chitotriosidase improved enzymatic assay for the human macrophage chitinase B Aguilera, K Ghauharali-van der Vlugt, MTJ Helmond, JMM Out, ... Journal of Biological Chemistry 278 (42), 40911-40916, 2003 | 197 | 2003 |
Identification of the Nef-associated kinase as p21-activated kinase 2 GH Renkema, A Manninen, DA Mann, M Harris, K Saksela Current biology 9 (23), 1407-1411, 1999 | 181 | 1999 |
Cyclic AMP-dependent protein kinase phosphorylates merlin at serine 518 independently of p21-activated kinase and promotes merlin-ezrin heterodimerization K Alfthan, L Heiska, M Grönholm, GH Renkema, O Carpén Journal of Biological Chemistry 279 (18), 18559-18566, 2004 | 165 | 2004 |
Identification of preferred protein interactions by phage‐display of the human Src homology‐3 proteome S Kärkkäinen, M Hiipakka, JH Wang, I Kleino, M Vähä‐Jaakkola, ... EMBO reports 7 (2), 186-191, 2006 | 159 | 2006 |
NANS-mediated synthesis of sialic acid is required for brain and skeletal development CDM van Karnebeek, L Bonafé, XY Wen, M Tarailo-Graovac, S Balzano, ... Nature genetics 48 (7), 777-784, 2016 | 143 | 2016 |
Synergistic activation of NFAT by HIV-1 nef and the Ras/MAPK pathway A Manninen, GH Renkema, K Saksela Journal of Biological Chemistry 275 (22), 16513-16517, 2000 | 137 | 2000 |
SH3-domain binding function of HIV-1 Nef is required for association with a PAK-related kinase A Manninen, M Hiipakka, M Vihinen, W Lu, BJ Mayer, K Saksela Virology 250 (2), 273-282, 1998 | 137 | 1998 |
CLPB Mutations Cause 3-Methylglutaconic Aciduria, Progressive Brain Atrophy, Intellectual Disability, Congenital Neutropenia, Cataracts, Movement Disorder SB Wortmann, S Ziętkiewicz, M Kousi, R Szklarczyk, TB Haack, ... The American Journal of Human Genetics 96 (2), 245-257, 2015 | 126 | 2015 |