| Intratumor heterogeneity and branched evolution revealed by multiregion sequencing M Gerlinger, AJ Rowan, S Horswell, J Larkin, D Endesfelder, E Gronroos, ... N Engl j Med 366, 883-892, 2012 | 6500 | 2012 |
| Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancer Multiple Leiomyoma Consortium Nature genetics 30 (4), 406, 2002 | 1425 | 2002 |
| p53 mutations in colorectal cancer. NR Rodrigues, A Rowan, ME Smith, IB Kerr, WF Bodmer, JV Gannon, ... Proceedings of the National Academy of Sciences 87 (19), 7555-7559, 1990 | 1277 | 1990 |
| Tracking the evolution of non–small-cell lung cancer M Jamal-Hanjani, GA Wilson, N McGranahan, NJ Birkbak, TBK Watkins, ... New England Journal of Medicine 376 (22), 2109-2121, 2017 | 1079 | 2017 |
| Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing M Gerlinger, S Horswell, J Larkin, AJ Rowan, MP Salm, I Varela, R Fisher, ... Nature genetics 46 (3), 225, 2014 | 1002 | 2014 |
| A genome-wide association scan of tag SNPs identifies a susceptibility variant for colorectal cancer at 8q24. 21 I Tomlinson, E Webb, L Carvajal-Carmona, P Broderick, Z Kemp, S Spain, ... Nature genetics 39 (8), 984-988, 2007 | 860 | 2007 |
| Spatial and temporal diversity in genomic instability processes defines lung cancer evolution EC de Bruin, N McGranahan, R Mitter, M Salm, DC Wedge, L Yates, ... Science 346 (6206), 251-256, 2014 | 855 | 2014 |
| Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution C Abbosh, NJ Birkbak, GA Wilson, M Jamal-Hanjani, T Constantin, ... Nature 545 (7655), 446-451, 2017 | 706 | 2017 |
| A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23. 3 IPM Tomlinson, E Webb, L Carvajal-Carmona, P Broderick, K Howarth, ... Nature genetics 40 (5), 623-630, 2008 | 599 | 2008 |
| Replication stress links structural and numerical cancer chromosomal instability RA Burrell, SE McClelland, D Endesfelder, P Groth, MC Weller, N Shaikh, ... Nature 494 (7438), 492-496, 2013 | 593 | 2013 |
| A genome-wide association study shows that common alleles of SMAD7 influence colorectal cancer risk P Broderick, L Carvajal-Carmona, AM Pittman, E Webb, K Howarth, ... Nature genetics 39 (11), 1315-1317, 2007 | 555 | 2007 |
| β-Catenin mutations in cell lines established from human colorectal cancers M Ilyas, IPM Tomlinson, A Rowan, M Pignatelli, WF Bodmer Proceedings of the National Academy of Sciences 94 (19), 10330-10334, 1997 | 535 | 1997 |
| APC mutations in sporadic colorectal tumors: A mutational “hotspot” and interdependence of the “two hits” AJ Rowan, H Lamlum, M Ilyas, J Wheeler, J Straub, A Papadopoulou, ... Proceedings of the National Academy of Sciences 97 (7), 3352-3357, 2000 | 508 | 2000 |
| The type of somatic mutation at APC in familial adenomatous polyposis is determined by the site of the germline mutation: a new facet to Knudson's' two-hit'hypothesis H Lamlum, M Ilyas, A Rowan, S Clark, V Johnson, J Bell, I Frayling, ... Nature medicine 5 (9), 1071-1075, 1999 | 431 | 1999 |
| Allele-specific HLA loss and immune escape in lung cancer evolution N McGranahan, R Rosenthal, CT Hiley, AJ Rowan, TBK Watkins, ... Cell 171 (6), 1259-1271. e11, 2017 | 409 | 2017 |
| Insertion-and-deletion-derived tumour-specific neoantigens and the immunogenic phenotype: a pan-cancer analysis S Turajlic, K Litchfield, H Xu, R Rosenthal, N McGranahan, JL Reading, ... The lancet oncology 18 (8), 1009-1021, 2017 | 394 | 2017 |
| Chromosomal instability confers intrinsic multidrug resistance AJX Lee, D Endesfelder, AJ Rowan, A Walther, NJ Birkbak, PA Futreal, ... Cancer research 71 (5), 1858-1870, 2011 | 370 | 2011 |
| Genetic and functional analyses of FH mutations in multiple cutaneous and uterine leiomyomatosis, hereditary leiomyomatosis and renal cancer, and fumarate … NA Alam, AJ Rowan, NC Wortham, PJ Pollard, M Mitchell, JP Tyrer, ... Human molecular genetics 12 (11), 1241-1252, 2003 | 336 | 2003 |
| Common genetic variants at the CRAC1 (HMPS) locus on chromosome 15q13. 3 influence colorectal cancer risk E Jaeger, E Webb, K Howarth, L Carvajal-Carmona, A Rowan, ... Nature genetics 40 (1), 26-28, 2008 | 331 | 2008 |
| Tracking cancer evolution reveals constrained routes to metastases: TRACERx renal S Turajlic, H Xu, K Litchfield, A Rowan, T Chambers, JI Lopez, D Nicol, ... Cell 173 (3), 581-594. e12, 2018 | 264 | 2018 |
Nicholas McGranahanGroup Leader, CRUK Lung Cancer Centre of Excellence, UCL Cancer InstituteVerified email at ucl.ac.uk
