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Kerstin Klein
Kerstin Klein
Center of Experimental Rheumatology, University Hospital Zurich
Verified email at usz.ch
Title
Cited by
Cited by
Year
Epigenetics in rheumatoid arthritis
K Klein, S Gay
Current opinion in rheumatology 27 (1), 76-82, 2015
1632015
The bromodomain protein inhibitor I-BET151 suppresses expression of inflammatory genes and matrix degrading enzymes in rheumatoid arthritis synovial fibroblasts
K Klein, PA Kabala, AM Grabiec, RE Gay, C Kolling, LL Lin, S Gay, ...
Annals of the rheumatic diseases 75 (2), 422-429, 2016
1612016
Epigenetically-driven anatomical diversity of synovial fibroblasts guides joint-specific fibroblast functions
M Frank-Bertoncelj, M Trenkmann, K Klein, E Karouzakis, H Rehrauer, ...
Nature communications 8 (1), 14852, 2017
1582017
Dual role of autophagy in stress‐induced cell death in rheumatoid arthritis synovial fibroblasts
M Kato, C Ospelt, RE Gay, S Gay, K Klein
Arthritis & rheumatology 66 (1), 40-48, 2014
1542014
Complex haplotypes of the PGC-1α gene are associated with carbohydrate metabolism and type 2 diabetes
H Oberkofler, V Linnemayr, R Weitgasser, K Klein, M Xie, B Iglseder, ...
Diabetes 53 (5), 1385-1393, 2004
1362004
The complement system drives local inflammatory tissue priming by metabolic reprogramming of synovial fibroblasts
J Friščić, M Böttcher, C Reinwald, H Bruns, B Wirth, SJ Popp, KI Walker, ...
Immunity 54 (5), 1002-1021. e10, 2021
1342021
Epigenetics in the pathogenesis of RA
C Ospelt, S Gay, K Klein
Seminars in immunopathology 39, 409-419, 2017
1002017
Epigenetic contributions in the development of rheumatoid arthritis
K Klein, C Ospelt, S Gay
Arthritis Research & Therapy 14, 1-7, 2012
882012
Role of peroxisome proliferator-activated receptor-γ coactivator-1α in the transcriptional regulation of the human uncoupling protein 2 gene in INS-1E cells
H Oberkofler, K Klein, TK Felder, F Krempler, W Patsch
Endocrinology 147 (2), 966-976, 2006
742006
Identification of a genetic variant for joint damage progression in autoantibody-positive rheumatoid arthritis
R Knevel, K Klein, K Somers, C Ospelt, JJ Houwing-Duistermaat, ...
Annals of the rheumatic diseases 73 (11), 2038-2046, 2014
702014
Epigenetic modifications in rheumatoid arthritis, a review
K Klein, S Gay
Current opinion in pharmacology 13 (3), 420-425, 2013
702013
Associations of the UCP2 gene locus with asymptomatic carotid atherosclerosis in middle-aged women
H Oberkofler, B Iglseder, K Klein, J Unger, M Haltmayer, F Krempler, ...
Arteriosclerosis, thrombosis, and vascular biology 25 (3), 604-610, 2005
692005
Retinol-binding protein 4 in polycystic ovary syndrome—association with steroid hormones and response to pioglitazone treatment
E Aigner, N Bachofner, K Klein, C De Geyter, F Hohla, W Patsch, C Datz
The Journal of Clinical Endocrinology & Metabolism 94 (4), 1229-1235, 2009
582009
Bromodomain protein inhibition: a novel therapeutic strategy in rheumatic diseases
K Klein
RMD open 4 (2), e000744, 2018
532018
ATP induced brain-derived neurotrophic factor expression and release from osteoarthritis synovial fibroblasts is mediated by purinergic receptor P2X4
K Klein, A Aeschlimann, S Jordan, R Gay, S Gay, H Sprott
PLoS One 7 (5), e36693, 2012
422012
The human organic anion transporter genes OAT5 and OAT7 are transactivated by hepatocyte nuclear factor-1α (HNF-1α)
K Klein, C Jüngst, J Mwinyi, B Stieger, F Krempler, W Patsch, JJ Eloranta, ...
Molecular pharmacology 78 (6), 1079-1087, 2010
402010
SIRT6 regulates the cigarette smoke-induced signalling in rheumatoid arthritis synovial fibroblasts
A Engler, F Niederer, K Klein, RE Gay, D Kyburz, GG Camici, S Gay, ...
Journal of molecular medicine 92, 757-767, 2014
352014
Interplay between genetic and epigenetic mechanisms in rheumatoid arthritis
M Frank-Bertoncelj, K Klein, S Gay
Epigenomics 9 (4), 493-504, 2017
342017
Functional genomics atlas of synovial fibroblasts defining rheumatoid arthritis heritability
X Ge, M Frank-Bertoncelj, K Klein, A McGovern, T Kuret, M Houtman, ...
Genome biology 22, 1-39, 2021
332021
The epigenetic architecture at gene promoters determines cell type-specific LPS tolerance
K Klein, M Frank-Bertoncelj, E Karouzakis, RE Gay, C Kolling, A Ciurea, ...
Journal of autoimmunity 83, 122-133, 2017
322017
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